Find the best Mississippi County Hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Mississippi County hotels
Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.8 out of 10, (622 reviews)
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
Annette
The price is ฿1,927
฿2,138 total
includes taxes & fees
23 Jan - 24 Jan
Eagle Inn Charleston
Eagle Inn CharlestonCharleston
6.6 out of 10, (105 reviews)
"Middle of nowhere hotel was ok"
David
The price is ฿1,877
฿2,083 total
includes taxes & fees
23 Jan - 24 Jan
Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
6.6 out of 10, (275 reviews)
"The quality was not what I expected for a "Quality Inn". It felt more light a Motel 6. I was not satisfied at all."
ReShena
The price is ฿2,206
฿2,448 total
includes taxes & fees
31 Jan - 1 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Mississippi County Hotel Reviews
TownePlace Suites by Marriott Sikeston
10/10 Excellent
Explore a world of travel with Expedia
Top cities in Mississippi County
Hotels near popular Attractions
More ways to book
Expedia's Latest Trends
Hotels
- Hotels near Worlds of Fun
- Hotels near Tha Pai Hot Springs
- 5 Star Hotels in Hat Chao Samran
- Gay-Friendly Hotels in Los Angeles County
- Promtsuk Buri Resort
- Hotels in Glen Carbon
- Hotels near Mahasarakham University
- Hotels near Silver Dollar City
- Hotels in Los Angeles County
- Hotels in Danok
- Hotels in Rich Fountain
- Sunshine Paradise Resort
- Hotels in Chang Khlan
Flights
Packages
