
Find hotels in East Prairie, MO from ฿2,018
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Our top choices for East Prairie hotels

Super 8 By Wyndham Marston
Super 8 By Wyndham MarstonMarston
8.2 out of 10, Very good, (53 reviews)
The price is ฿2,136
฿2,440 total
includes taxes & fees
3 Apr - 4 Apr

Country Hearth Inn & Suites Union City
Country Hearth Inn & Suites Union CityUnion City
8.6 out of 10, Excellent, (557 reviews)
The price is ฿2,077
฿2,466 total
includes taxes & fees
28 Mar - 29 Mar

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,001 reviews)
The price is ฿3,099
฿3,563 total
includes taxes & fees
5 Apr - 6 Apr

The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
6.8 out of 10, (410 reviews)
The price is ฿1,899
฿2,107 total
includes taxes & fees
29 Mar - 30 Mar

Sleep Inn at Discovery Park of America
Sleep Inn at Discovery Park of AmericaUnion City
9.2 out of 10, Wonderful, (368 reviews)
The price is ฿2,631
฿3,124 total
includes taxes & fees
5 Apr - 6 Apr

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (65 reviews)
The price is ฿3,330
฿3,770 total
includes taxes & fees
5 Apr - 6 Apr

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very good, (754 reviews)
The price is ฿2,159
฿2,461 total
includes taxes & fees
29 Mar - 30 Mar

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (513 reviews)
The price is ฿3,254
฿3,685 total
includes taxes & fees
12 Apr - 13 Apr

Quality Inn Union City US 51
Quality Inn Union City US 51Union City
8.4 out of 10, Very good, (500 reviews)
The price is ฿2,605
฿3,093 total
includes taxes & fees
29 Mar - 30 Mar

Reelfoot Lake Inn
Reelfoot Lake InnTiptonville
7.2 out of 10, Good, (475 reviews)
The price is ฿2,299
฿2,638 total
includes taxes & fees
29 Mar - 30 Mar

New Orleans Inn Portageville
New Orleans Inn PortagevillePortageville
8.0 out of 10, Very good, (754 reviews)
The price is ฿1,869
฿2,018 total
includes taxes & fees
29 Mar - 30 Mar

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.8 out of 10, (627 reviews)
The price is ฿2,047
฿2,272 total
includes taxes & fees
28 Mar - 29 Mar

Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very good, (1,000 reviews)
The price is ฿3,054
฿3,481 total
includes taxes & fees
2 Apr - 3 Apr

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (450 reviews)
The price is ฿3,066
฿3,472 total
includes taxes & fees
12 Apr - 13 Apr

TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (15 reviews)
The price is ฿3,755
฿4,252 total
includes taxes & fees
5 Apr - 6 Apr

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
7.2 out of 10, Good, (1,000 reviews)
The price is ฿2,242
฿2,555 total
includes taxes & fees
29 Mar - 30 Mar

Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
6.6 out of 10, (282 reviews)
The price is ฿2,519
฿2,795 total
includes taxes & fees
28 Mar - 29 Mar

Hampton Inn Union City
Hampton Inn Union CityUnion City
9.6 out of 10, Exceptional, (175 reviews)
The price is ฿4,542
฿5,393 total
includes taxes & fees
26 Apr - 27 Apr

Eagle Inn Charleston
Eagle Inn CharlestonCharleston
6.6 out of 10, (105 reviews)
The price is ฿2,089
฿2,318 total
includes taxes & fees
28 Mar - 29 Mar

Travel Inn
Travel InnMarston
6.0 out of 10, (119 reviews)
The price is ฿1,813
฿2,070 total
includes taxes & fees
30 Mar - 31 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions
Learn more about East Prairie
Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

Top East Prairie Hotel Reviews

Fairfield Inn & Suites by Marriott Sikeston
10/10 Excellent
More cheap stays in East Prairie

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
100 Matthews Lane Sikeston MO
The price is ฿2,159 per night from 29 Mar to 30 Mar
฿2,159
฿2,461 total
29 Mar - 30 Mar
includes taxes & fees
8.4/10 Very Good! (754 reviews)









































































