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Our top choices for Cherokee Seneca hotels

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, 7 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1,000 reviews)
"Excellent place. "
United States
Anatole
The price is ฿4,405
฿5,340 total
includes taxes & fees
18 Jan - 19 Jan
21c Museum Hotel Louisville

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 7.1 km from Cherokee Seneca
8.8 out of 10, Excellent, (1,680 reviews)
"Room was clean and the beds were very comfortable. Would definitely stay here again."
United States
Talva
The price is ฿2,575
฿3,030 total
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn Express & Suites Louisville Downtown by IHG

SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 5.9 km from Cherokee Seneca
8.4 out of 10, Very good, (1,001 reviews)
"Great location, spacious room, friendly staff"
United States
Valeriia
The price is ฿3,172
฿3,732 total
includes taxes & fees
19 Jan - 20 Jan
SpringHill Suites by Marriott Louisville Downtown

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 6.5 km from Cherokee Seneca
9.0 out of 10, Wonderful, (3,982 reviews)
"Great stay"
United States
Carlos
The price is ฿4,223
฿4,969 total
includes taxes & fees
28 Jan - 29 Jan
Galt House Hotel Trademark Collection by Wyndham

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
8.8 out of 10, Excellent, (1,002 reviews)
"Great hotel close to 4th street. Overall nice stay. "
United States
Collin
The price is ฿4,522
฿5,320 total
includes taxes & fees
30 Jan - 31 Jan
Hyatt Regency Louisville

Tru by Hilton Shepherdsville Louisville South

Tru by Hilton Shepherdsville Louisville South
2.5 star property
19.1 km from Cherokee Seneca
9.2 out of 10, Wonderful, (854 reviews)
"Very friendly staff, very clean and comfy rooms"
United States
Trevor
The price is ฿2,832
฿3,153 total
includes taxes & fees
24 Jan - 25 Jan
Tru by Hilton Shepherdsville Louisville South

Fairfield Inn & Suites by Marriott Louisville Airport

Fairfield Inn & Suites by Marriott Louisville Airport
2.5 star property
7.3 km from Cherokee Seneca
8.8 out of 10, Excellent, (687 reviews)
"Staff was amazing, hotel was great."
United States
Rickey
The price is ฿2,920
฿3,436 total
includes taxes & fees
19 Jan - 20 Jan
Fairfield Inn & Suites by Marriott Louisville Airport

Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown
3.5 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
8.4 out of 10, Very good, (1,016 reviews)
"Clean, great location and amazing customer service "
United States
Jamie
The price is ฿2,915
฿3,429 total
includes taxes & fees
1 Feb - 2 Feb
Hilton Garden Inn Louisville Downtown

Courtyard by Marriott Louisville Airport

Courtyard by Marriott Louisville Airport
3.0 star property
7.1 km from Cherokee Seneca
9.2 out of 10, Wonderful, (363 reviews)
"Amenities, restaurants, location, room was nice "
United States
Anitra
The price is ฿3,360
฿3,953 total
includes taxes & fees
19 Jan - 20 Jan
Courtyard by Marriott Louisville Airport

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 6.2 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1,760 reviews)
"Beautiful, spacious hotel. Spotless room, kind and helpful staff."
United States
Gizella
The price is ฿5,251
฿6,178 total
includes taxes & fees
19 Jan - 20 Jan
Omni Louisville Hotel

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 6.9 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1,001 reviews)
"Very friendly and clean! Great stay! "
United States
Jackie
The price is ฿3,322
฿3,908 total
includes taxes & fees
1 Feb - 2 Feb
Homewood Suites by Hilton Louisville Downtown, KY

Marriott Louisville East

Marriott Louisville East
4.0 star property
Jeffersontown, 9.9 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,000 reviews)
"Great stay"
United States
Brad
The price is ฿3,443
฿4,051 total
includes taxes & fees
25 Jan - 26 Jan
Marriott Louisville East

Drury Inn & Suites Louisville North

Drury Inn & Suites Louisville North
3.0 star property
12.5 km from Cherokee Seneca
9.6 out of 10, Exceptional, (1,001 reviews)
"Excellent place to stay."
United States
Robert
The price is ฿3,140
฿3,694 total
includes taxes & fees
22 Jan - 23 Jan
Drury Inn & Suites Louisville North

Hilton Garden Inn Louisville Mall of St. Matthews

Hilton Garden Inn Louisville Mall of St. Matthews
3.0 star property
St. Matthews, 5.2 km from Cherokee Seneca
9.2 out of 10, Wonderful, (885 reviews)
"Great view, comfortably slept and amazing staff"
United States
Rebecca
The price is ฿3,040
฿3,577 total
includes taxes & fees
25 Jan - 26 Jan
Hilton Garden Inn Louisville Mall of St. Matthews

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
Downtown Louisville, 6.1 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,002 reviews)
"Great room and location and always a plus when pets can stay for free!"
United States
Elizabeth
The price is ฿3,156
฿3,713 total
includes taxes & fees
1 Feb - 2 Feb
Aloft Louisville Downtown

Hampton Inn Simpsonville

Hampton Inn Simpsonville
2.5 star property
29.6 km from Cherokee Seneca
9.4 out of 10, Exceptional, (912 reviews)
"Would stay again"
United States
Chris
The price is ฿2,807
฿3,124 total
includes taxes & fees
23 Jan - 24 Jan
Hampton Inn Simpsonville

Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown
2.5 star property
Downtown Louisville, 6 km from Cherokee Seneca
8.4 out of 10, Very good, (1,001 reviews)
"Great stay!!!"
United States
Bridget
The price is ฿2,920
฿3,436 total
includes taxes & fees
19 Jan - 20 Jan
Fairfield Inn & Suites by Marriott Louisville Downtown

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,151 reviews)
"Great room and breakfast. Close to several nice restaurants."
United States
Crystal
The price is ฿3,692
฿4,344 total
includes taxes & fees
26 Jan - 27 Jan
Embassy Suites Louisville Downtown

Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property
4.0 star property
6 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1,756 reviews)
"Rooms are very nice we had a great time "
United States
william
Derby City Gaming & Hotel - A Churchill Downs Property

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 5.8 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1,001 reviews)
"Enjoyed our stay."
United States
Christian
The price is ฿3,285
฿3,865 total
includes taxes & fees
15 Feb - 16 Feb
Cambria Hotel Louisville Downtown-Whiskey Row
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Cherokee Seneca

Find the best Cherokee Seneca areas for the activities you enjoy most.

Downtown Louisville

The cultural heart of the city beats with baseball, boxing and music, with sporting fields, live bands and a center for Muhammad Ali, the city’s most famous son.

St. Matthews

St. Matthews is noteworthy for its shopping, and you can make a stop at top attractions like Mall St. Matthews and Saint Matthews Pavilion Shopping Center.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

Old Louisville

Old Louisville is known for its ample dining options, and you can make a stop by Ohio River Valley and Conrad-Caldwell House Museum while in the area.

Top Cherokee Seneca Hotel Reviews

Frequently asked questions

What is Cherokee Seneca like?
You'll be sure to have fun exploring Louisville's Cherokee Seneca neighbourhood.
If I need to cancel my hotel reservation in Cherokee Seneca, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to review the best deals in Cherokee Seneca.
What is there to do around this Louisville neighbourhood?
Peterson-Dumesnil House, Historic Frankfort Avenue and Colonel Sanders' Grave are just a few of the places to visit in and around Cherokee Seneca. Muhammad Ali Gravesite and Mid City Mall Shopping Center are also worth a visit when you're out sightseeing in Louisville.