Photo by Abby Fieldhouse

Search Hotels in Cherokee Seneca, Louisville

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Cherokee Seneca hotels

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, 7 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1,003 reviews)
"Excellent place. "
United States
Anatole
The price is ฿3,956
฿4,811 total
includes taxes & fees
8 Feb - 9 Feb
21c Museum Hotel Louisville

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 7.1 km from Cherokee Seneca
8.8 out of 10, Excellent, (1,673 reviews)
"Room was clean and the beds were very comfortable. Would definitely stay here again."
United States
Talva
The price is ฿2,578
฿3,033 total
includes taxes & fees
18 Jan - 19 Jan
Holiday Inn Express & Suites Louisville Downtown by IHG

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
Downtown Louisville, 6.1 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,000 reviews)
"Great room and location and always a plus when pets can stay for free!"
United States
Elizabeth
The price is ฿3,160
฿3,718 total
includes taxes & fees
1 Feb - 2 Feb
Aloft Louisville Downtown

Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property
4.0 star property
6 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1,747 reviews)
"Great place to stay"
United States
april
Derby City Gaming & Hotel - A Churchill Downs Property

Drury Inn & Suites Louisville North

Drury Inn & Suites Louisville North
3.0 star property
12.5 km from Cherokee Seneca
9.6 out of 10, Exceptional, (1,001 reviews)
"Excellent place to stay."
United States
Robert
The price is ฿3,132
฿3,686 total
includes taxes & fees
8 Feb - 9 Feb
Drury Inn & Suites Louisville North

Marriott Louisville East

Marriott Louisville East
4.0 star property
Jeffersontown, 9.9 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,000 reviews)
"Great stay"
United States
Brad
The price is ฿3,715
฿4,371 total
includes taxes & fees
18 Jan - 19 Jan
Marriott Louisville East

The Grady

The Grady
4.0 star property
Downtown Louisville, 6.8 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1,000 reviews)
"Such an amazing hotel...restaurant is delicious! "
United States
Craig
The Grady

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
8.8 out of 10, Excellent, (1,001 reviews)
"Great hotel close to 4th street. Overall nice stay. "
United States
Collin
The price is ฿4,636
฿5,455 total
includes taxes & fees
21 Jan - 22 Jan
Hyatt Regency Louisville

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 7.1 km from Cherokee Seneca
9.2 out of 10, Wonderful, (522 reviews)
"Clean, great staff, great breakfast ! "
United States
Sondra
The price is ฿3,039
฿3,575 total
includes taxes & fees
8 Feb - 9 Feb
Towneplace Suites By Marriott Louisville Downtown

Tru by Hilton Shepherdsville Louisville South

Tru by Hilton Shepherdsville Louisville South
2.5 star property
19.1 km from Cherokee Seneca
9.2 out of 10, Wonderful, (850 reviews)
"Very friendly staff, very clean and comfy rooms"
United States
Trevor
The price is ฿2,813
฿3,131 total
includes taxes & fees
17 Jan - 18 Jan
Tru by Hilton Shepherdsville Louisville South

Fairfield Inn & Suites by Marriott Louisville Northeast

Fairfield Inn & Suites by Marriott Louisville Northeast
2.5 star property
12.6 km from Cherokee Seneca
9.2 out of 10, Wonderful, (619 reviews)
"The rooms were clean and breakfsst was good"
Canada
Walaa
The price is ฿3,034
฿3,569 total
includes taxes & fees
20 Jan - 21 Jan
Fairfield Inn & Suites by Marriott Louisville Northeast

Sheraton Louisville Riverside by Marriott

Sheraton Louisville Riverside by Marriott
3.5 star property
6.4 km from Cherokee Seneca
8.2 out of 10, Very good, (1,002 reviews)
"The room,staff and dining area was awesome. Strongly recommend this location"
United States
Michael
The price is ฿2,641
฿2,984 total
includes taxes & fees
25 Jan - 26 Jan
Sheraton Louisville Riverside by Marriott

Hyatt House Louisville East

Hyatt House Louisville East
2.0 star property
9.2 km from Cherokee Seneca
9.6 out of 10, Exceptional, (1,000 reviews)
"We always stay here,nice staff, clean and convenient for shopping and nice restaurants."
United States
Retina
The price is ฿3,446
฿4,054 total
includes taxes & fees
17 Jan - 18 Jan
Hyatt House Louisville East

Hilton Garden Inn Louisville Mall of St. Matthews

Hilton Garden Inn Louisville Mall of St. Matthews
3.0 star property
St. Matthews, 5.2 km from Cherokee Seneca
9.2 out of 10, Wonderful, (877 reviews)
"Great view, comfortably slept and amazing staff"
United States
Rebecca
The price is ฿2,867
฿3,374 total
includes taxes & fees
18 Jan - 19 Jan
Hilton Garden Inn Louisville Mall of St. Matthews

Residence Inn by Marriott Louisville Downtown

Residence Inn by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 5.6 km from Cherokee Seneca
8.8 out of 10, Excellent, (1,002 reviews)
"Clean room, great location,walkable to everything, parking in and out no hassle, very nice staff!"
United States
Russell
The price is ฿2,924
฿3,440 total
includes taxes & fees
8 Feb - 9 Feb
Residence Inn by Marriott Louisville Downtown

Hampton Inn Simpsonville

Hampton Inn Simpsonville
2.5 star property
29.6 km from Cherokee Seneca
9.4 out of 10, Exceptional, (909 reviews)
"Would stay again"
United States
Chris
The price is ฿2,800
฿3,116 total
includes taxes & fees
17 Jan - 18 Jan
Hampton Inn Simpsonville

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,148 reviews)
"Great room and breakfast. Close to several nice restaurants."
United States
Crystal
The price is ฿3,816
฿4,489 total
includes taxes & fees
26 Jan - 27 Jan
Embassy Suites Louisville Downtown

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 5.8 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1,001 reviews)
"Enjoyed our stay."
United States
Christian
The price is ฿3,280
฿3,860 total
includes taxes & fees
17 Jan - 18 Jan
Cambria Hotel Louisville Downtown-Whiskey Row

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 6.9 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1,000 reviews)
"Very friendly and clean! Great stay! "
United States
Jackie
The price is ฿3,223
฿3,792 total
includes taxes & fees
26 Jan - 27 Jan
Homewood Suites by Hilton Louisville Downtown, KY

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 4.9 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1,026 reviews)
"Spotless room and courteous staff "
United States
Mary
The price is ฿3,650
฿4,295 total
includes taxes & fees
12 Jan - 13 Jan
Hotel Genevieve part of JdV by Hyatt
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Cherokee Seneca

Find the best Cherokee Seneca areas for the activities you enjoy most.

Downtown Louisville

The cultural heart of the city beats with baseball, boxing and music, with sporting fields, live bands and a center for Muhammad Ali, the city’s most famous son.

St. Matthews

St. Matthews is noteworthy for its shopping, and you can make a stop at top attractions like Mall St. Matthews and Saint Matthews Pavilion Shopping Center.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

Old Louisville

Old Louisville is known for its ample dining options, and you can make a stop by Ohio River Valley and Conrad-Caldwell House Museum while in the area.

Top Cherokee Seneca Hotel Reviews

Frequently asked questions

What is Cherokee Seneca like?
You'll be sure to have fun exploring Louisville's Cherokee Seneca neighbourhood.
If I need to cancel my hotel reservation in Cherokee Seneca, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to review the best deals in Cherokee Seneca.
What is there to do around this Louisville neighbourhood?
Peterson-Dumesnil House, Historic Frankfort Avenue and Colonel Sanders' Grave are just a few of the places to visit in and around Cherokee Seneca. Muhammad Ali Gravesite and Mid City Mall Shopping Center are also worth a visit when you're out sightseeing in Louisville.