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Check prices for these dates

Tonight
25 Sep - 26 Sep
Tomorrow
26 Sep - 27 Sep
This weekend
25 Sep - 27 Sep
Next weekend
2 Oct - 4 Oct

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Our top choices for Calle 50 hotels

A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A spacious hotel lobby with modern furniture, large windows, and a city view.
A spacious lobby with a curved ceiling, a central staircase, and a reception desk.
A modern building with a sign reading 'HYATT REGENCY.'

1. Hyatt Regency Panama City

Hyatt Regency Panama City
Campo Alegre, 1 km from Calle 50
United States
LaQuan Jaden
฿6,250
฿6,876 total
includes taxes & fees
3 Oct - 4 Oct
Hyatt Regency Panama City
A covered outdoor seating area with a view of a city skyline and water.
A hotel room with two beds, a desk, and a large window offering a city view.
A restaurant with large windows offering a view of a city skyline and palm trees.
A cityscape with high-rise buildings, a waterfront, and a modern sculpture.

2. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
Punta Paitilla, 1.3 km from Calle 50
Canada
Catherine
฿3,983
฿4,381 total
includes taxes & fees
27 Sept - 28 Sept
Plaza Paitilla Inn Hotel
A modern lobby with a chandelier, seating area, reception desk, and a staircase.
A lobby with a reception desk, seating area, and a bar.
A hotel dining area with wicker chairs, a bar counter, and pendant lighting.
A dining area with a glass table, wicker chairs, a plate of fruit, and a cocktail glass.

3. The Executive Hotel

The Executive Hotel
Campo Alegre, 1.2 km from Calle 50
United States
Sandra
฿2,969
฿3,266 total
includes taxes & fees
21 Oct - 22 Oct
The Executive Hotel
A hotel named PRINCIPE with a modern facade and large glass windows.
A swimming pool with lounge chairs and a table.
A hotel lobby with a reception desk, seating area, and a visible sign for 'PRINCIPES HOTEL & SQUITES'.
A hotel reception area with a modern design, featuring a reception desk, white chairs, and a visible fire feature.

4. Principe Hotel and Suites

Principe Hotel and Suites
El Cangrejo, 0.9 km from Calle 50
United States
Eliel
฿1,976
฿2,174 total
includes taxes & fees
27 Sept - 28 Sept
Principe Hotel and Suites
A rooftop pool with sun loungers and a city skyline in the background.
A modern hotel room with a large bed, a desk, a chair, and a wardrobe.
A bar area with a curved counter, multiple screens, and a patterned carpet.
A long, narrow hallway with a wooden floor and light-colored walls.

5. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
El Cangrejo, 1.4 km from Calle 50
United States
kevin
฿2,382
฿4,458 total
includes taxes & fees
22 Oct - 23 Oct
Waymore Hotel Spa & Casino
A rooftop pool with clear blue water, surrounded by palm trees and a city skyline in the background.
A restaurant with wooden tables and chairs, hanging plants, and circular wall decorations.
A modern hotel room with a large bed, a wardrobe, a desk with a chair, and a decorative wall piece.
An outdoor café with multiple wooden tables and chairs, surrounded by greenery and decorative elements.

6. Gran Evenia Panama

Gran Evenia Panama
El Cangrejo, 1 km from Calle 50
United States
Johneil
฿3,396
฿3,735 total
includes taxes & fees
1 Oct - 2 Oct
Gran Evenia Panama
A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.
A spacious lobby with large windows, a curved ceiling, and a seating area with a patterned rug.
A hotel room with a bed and a view of a cityscape through sheer curtains.
A bar area with a variety of liquor bottles, a counter, and seating with tables and chairs.

7. Novotel Panama City

Novotel Panama City
El Cangrejo, 1.1 km from Calle 50
United States
Philip
฿3,856
฿4,241 total
includes taxes & fees
4 Oct - 5 Oct
Novotel Panama City
A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.
A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.
A modern hotel room with a dining area, a TV, and a city view.

8. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Campo Alegre, 0.7 km from Calle 50
United States
Sandrelly
฿4,601
฿5,061 total
includes taxes & fees
28 Sept - 29 Sept
Hotel Riu Plaza Panama
A rooftop pool with lounge chairs and a city skyline view.
A gym with treadmills, elliptical machines, free weights, and a bench.
A woman sitting on a bed in a hotel room with a city view.
A hotel room with a bed, a sofa, an ottoman, a wall-mounted lamp, and a wardrobe.

9. Hotel Dann Carlton Marinn Place Panama Financial District

Hotel Dann Carlton Marinn Place Panama Financial District
Campo Alegre, 1.2 km from Calle 50
United States
Eliana
฿2,591
฿3,770 total
includes taxes & fees
30 Sept - 1 Oct
Hotel Dann Carlton Marinn Place Panama Financial District
A hotel entrance with a covered walkway, large windows, and a well-maintained garden area.
A lobby with seating areas, a reception desk, and a chandelier.
A hotel reception area with a desk, chairs, and a computer.
A hotel room with a bed, a desk, a chair, and a sofa.

10. Hotel Milan

Hotel Milan
El Cangrejo, 1.3 km from Calle 50
United States
Angelo
฿1,337
฿1,471 total
includes taxes & fees
1 Oct - 2 Oct
Hotel Milan
A poolside area with lounge chairs and a view of the ocean.
A modern building with a symmetrical facade, multiple balconies, and a central atrium with lighting.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.
A terrace with seating and a view of the ocean.

11. JW Marriott Panama

JW Marriott Panama
Punta Pacifica, 1.5 km from Calle 50
United States
Nemanja
฿9,345
฿10,280 total
includes taxes & fees
24 Oct - 25 Oct
JW Marriott Panama
A high-rise hotel with multiple floors, a prominent "Residence Inn by Marriott" sign, and a "Panama Clinic" sign.
A modern hotel pool with a glass barrier, surrounded by high-rise buildings and a sunset view.
A hotel room with two beds, a sofa, a bench, a TV, and a view of buildings.
A modern bar area with multiple seating options and a view of the cityscape.

12. Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
Punta Paitilla, 1 km from Calle 50
United States
Cassandre
฿6,284
฿6,912 total
includes taxes & fees
2 Oct - 3 Oct
Residence Inn by Marriott Panama City
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.
A rooftop swimming pool with a cityscape view, glass railings, and a modern architectural design.
A bar area with a long counter, multiple bar stools, and a television screen. There are large windows providing natural light and a view of the outdoors.
A person performing a yoga pose in a living room with a large window and a sofa.

13. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
Bella Vista, 1.1 km from Calle 50
United States
Juliet
฿7,074
฿7,782 total
includes taxes & fees
4 Oct - 5 Oct
Bristol Panama, a Registry Collection Hotel
An outdoor patio area with tables and chairs, a pool, and a covered seating area.
A staircase with a red handrail leading to an upper floor.
A hallway with a white wall featuring a motivational quote.
A small, clean room with a white air conditioner, a white refrigerator, a flat-screen TV mounted on the wall, and a bed with a white mattress.

14. Hostal Familiar Carmencita - Hostel

Hostal Familiar Carmencita - Hostel
Bella Vista, 1.1 km from Calle 50
United States
Brooke
฿1,435
฿1,578 total
includes taxes & fees
26 Sept - 27 Sept
Hostal Familiar Carmencita - Hostel
A modern building with a sign reading "LA RESIDENCE" and a car parked in front.
A modern hotel lobby with sofas, a coffee table, and a reception desk.
A bedroom with a large TV mounted on a marble wall, a bed, and a wooden cabinet.
A spacious living area with modern furniture, a round coffee table, and a large window offering a view of the outdoors.

15. La Résidence Panamá

La Résidence Panamá
Campo Alegre, 1 km from Calle 50
United States
Mohamad
฿4,332
฿4,765 total
includes taxes & fees
27 Sept - 28 Sept
La Résidence Panamá
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.
A modern hotel room with a large window offering a city view, a chandelier, and a cozy seating area.
An indoor swimming pool with lounge chairs and a modern interior design.
A spacious lobby with a staircase, seating area, and a bar.

16. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
Punta Paitilla, 0.9 km from Calle 50
United States
Armando
฿4,619
฿5,081 total
includes taxes & fees
11 Oct - 12 Oct
Las Americas Golden Tower Panama
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.
A coastal building complex with multiple structures, a prominent tower, and a beach in the foreground.
A modern reception area with a wooden panel wall, a sign indicating 'Marriott Bonvoy', and three reception desks with digital displays.
A modern lounge area with a wooden partition, a bar with a variety of bottles, and a seating area with chairs.

17. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
San Francisco, 0.4 km from Calle 50
United States
Holly
฿3,947
฿4,342 total
includes taxes & fees
10 Oct - 11 Oct
Courtyard by Marriott Panama Multiplaza Mall
An outdoor seating area with wooden tables and chairs, surrounded by potted plants and a yellow wall.
A dining area with wooden tables and chairs, a staircase, and a sofa.
A group of people seated at a wooden table in a restaurant with a staircase in the background.
A hotel room with two beds, a sofa, and a brick wall with artwork.

18. Panama House Bed & Breakfast

Panama House Bed & Breakfast
Bella Vista, 1 km from Calle 50
United States
Mark
฿978
฿1,076 total
includes taxes & fees
30 Sept - 1 Oct
Panama House Bed & Breakfast
A rooftop pool with blue lounge chairs and a city skyline view.
A modern interior with a seating area, a wine rack, and a bar.
A modern building with a glass entrance, seating area, and a reception desk.
A modern lounge area with white furniture, glass tables, and a city view.

19. Best Western Plus Panama Zen Hotel

Best Western Plus Panama Zen Hotel
El Cangrejo, 1.1 km from Calle 50
United States
Angelique
฿3,530
฿3,883 total
includes taxes & fees
26 Sept - 27 Sept
Best Western Plus Panama Zen Hotel
A modern living room with a sofa, armchair, dining table, and kitchen area with a TV and appliances.
A modern kitchen with a dining area, a flat-screen TV, and a view of the cityscape through the window.
A swimming pool with clear water, surrounded by high-rise buildings under a partly cloudy sky.
A modern living room with a glass dining table, black chairs, a grey sofa, and a large window with a city view.

20. Modern Apartments at The Gray Prime Location

Modern Apartments at The Gray Prime Location
Campo Alegre, 1.4 km from Calle 50
United States
Tiyania
฿2,735
฿3,008 total
includes taxes & fees
8 Oct - 9 Oct
Modern Apartments at The Gray Prime Location
View all properties

Compare popular hotels close to Calle 50

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
Hyatt Regency Panama City
9.6
Exceptional
458 reviews
View
A covered outdoor seating area with a view of a city skyline and water.
Plaza Paitilla Inn Hotel
9.4
Exceptional
2,238 reviews
View
A modern lobby with a chandelier, seating area, reception desk, and a staircase.
The Executive Hotel
9.2
Wonderful
1,266 reviews
View
A hotel named PRINCIPE with a modern facade and large glass windows.
Principe Hotel and Suites
9.0
Wonderful
2,073 reviews
View
A rooftop pool with sun loungers and a city skyline in the background.
Waymore Hotel Spa & Casino
9.0
Wonderful
1,165 reviews
View

Top Calle 50 Hotel Reviews

Decapolis Hotel Panama City

Decapolis Hotel Panama City

10/10 Excellent
"Buena ubicación, buen desayuno, zona segura accesible y se puede andar a pie en los alrededores, muy recomendado, cerca centro comercial y restaurantes."
Jesus Edilberto 5-night trip
Posted 12 hours ago
Decapolis Hotel Panama City
Hyatt Regency Panama City

Hyatt Regency Panama City

10/10 Excellent
"The Hyatt Regency is awesome I’d definitely recommend staying there."
LaQuan Jaden 4-night trip
Posted 22 hours ago
Hyatt Regency Panama City
Renaissance Panama City Hotel

Renaissance Panama City Hotel

8/10 Good
"Beautiful property. I enjoyed the courteous nature of the staff."
Shelly-Ann 3-night trip
Posted 1 day ago
Renaissance Panama City Hotel
The Executive Hotel

The Executive Hotel

10/10 Excellent
"Very friendly staff, clean rooms and amenities. Great location, walking distance to many touristic attractions and to the metro"
Maria 10-night trip
Posted 2 days ago
The Executive Hotel
Nomada Container Hotel Panama City

Nomada Container Hotel Panama City

10/10 Excellent
"I liked the convenience, it was easy to access, comfortable, and very centrally located."
Antonio 1-night trip
Posted 9 days ago
Nomada Container Hotel Panama City

Other attractions near Calle 50

A cityscape with a rainbow over buildings.
Photo by Fabiola Tile

Multiplaza Pacific Mall

9.0/10 (4,497 reviews)
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
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A spiraling skyscraper against a clear blue sky.
Photo by My World

Soho City Center

You can enjoy retail therapy at Soho City Center during your trip to Panama City. Discover the area's shops or seek out its local tours.
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A nighttime cityscape with illuminated skyscrapers and a river reflecting the lights.

Avenida Balboa

8.8/10 (3,608 reviews)
You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.
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Bingo 90

7.0/10 (12 reviews)
Why not roll the dice with a visit to Bingo 90 during your travels in Panama City? Visit the casinos and shops in this vibrant area.
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Pacific Center

You can browse for the perfect souvenirs at Pacific Center during your visit to Panama City. You can enjoy the restaurants while in the area.
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National Shrine of the Heart of Mary

9.0/10 (17 reviews)
You can learn about the history of Panama City with a trip to National Shrine of the Heart of Mary. Stroll along the seaside or visit the shops in this vibrant area.
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Multicentro Panama

8.2/10 (274 reviews)
During your trip to Panama City, you can find the perfect gifts to bring home at Multicentro Panama. Stroll along the seaside or visit the casinos in this vibrant area.
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Crown Casino

7.8/10 (412 reviews)
Why not roll the dice with a visit to Crown Casino during your visit to Panama City? Stroll along the seaside or visit the casinos in this vibrant area.
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Frequently asked questions

What's the area like around Calle 50?
Calle 50 is located in Panama City. This welcoming area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, take a look at the 478 hotels and other accommodation options you'll find within a mile.
What's the best place to stay near Calle 50?
Adjacent to Calle 50, Courtyard by Marriott Panama Multiplaza Mall is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices within a short distance include Hotel Riu Plaza Panama and Megapolis Hotel Panamá.
How many hotels can I expect to find near Calle 50?
Expedia has 478 hotels and other accommodation options within a mile from Calle 50.
If I need to cancel the hotel reservation for my stay near Calle 50, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to review the best options available near Calle 50.
What can I see and do near Calle 50?
You'll want to browse the collections at Interoceanic Canal Museum, Biomuseo and National Bank House Museum. Iglesia del Carmen, Panama Viejo and Panama Canal Railway are notable landmarks to explore if you're in the area. You can catch a show at National Theater, Anita Villalaz Theater and Amador Theater.
How can I get to Calle 50?
Nearby metro stations include Iglesia del Carmen Station and Vía Argentina Station. If you'd like to explore farther outside of the area, you may want a car rental for your journey.