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21C Museum Hotel St Louis

4.5 star property
Luxury hotel with fitness centre and steam room

Choose dates to view prices

Photo gallery for 21C Museum Hotel St Louis

Exterior
Indoor pool
Billiards
Bar (on property)
Interior
Nestled in the heart of St. Louis, 21C Museum Hotel St Louis offers a luxurious retreat with an indoor pool, coffee shop/cafe, and gym. Indulge in a massage at the spa or enjoy billiards at the bar while relishing cooked-to-order breakfast options.

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Pool
  • Bar
  • Spa
  • Gym
  • 24/7 front desk
The current price is ฿4,955
฿5,957 total
includes taxes & fees
31 Aug - 1 Sept

Room options

Available filters for rooms
Showing 15 of 15 rooms

Loft, 2 Queen Beds

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 40 sq m
  • Sleeps 4
  • 2 Queen Beds

Luxury Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Separate bath and shower
Private bathroom
  • 51 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Room (Bunk Bed)

Room (Bunk Bed) | 1 bedroom, in-room safe, desk, laptop workspace

Room (Bunk Bed)

8.0 out of 10
Very good
(6 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Private bathroom
Bathrobes
  • 22 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Single Bunk Bed

Deluxe Room, Accessible (Accessible)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 25 sq m
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (Library)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 68 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (21C)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Separate bath and shower
Private bathroom
  • 104 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 36 sq m
  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed | 1 bedroom, in-room safe, desk, laptop workspace

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(68 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 29 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 48 sq m
  • Sleeps 2
  • 1 Double Bed

View all photos for Deluxe Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Double Room, 2 Queen Beds

8.6 out of 10
Excellent
(19 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 34 sq m
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 36 sq m
  • Sleeps 4
  • 1 Double Bed

View all photos for Room, 1 King Bed, Corner

Room, 1 King Bed, Corner | 1 bedroom, in-room safe, desk, laptop workspace

Room, 1 King Bed, Corner

8.8 out of 10
Excellent
(23 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 30 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 48 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Suite, 1 King Bed

9.2 out of 10
Wonderful
(5 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 48 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Luxury Double Room, 2 Queen Beds

9.0 out of 10
Wonderful
(20 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Private bathroom
Bathrobes
  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

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About the area

Located in St. Louis, 21C Museum Hotel St Louis is in the city centre. St. Louis Union Station and Gateway Arch are notable landmarks, and the area's natural beauty can be seen at Mississippi River and Forest Park. Check out an event or a game at Busch Stadium, and consider making time for St. Louis Zoo, a top attraction not to be missed.
Visit our St. Louis travel guideOpens in a new window
Map
1528 Locust street, St. Louis, MO, 63103

What's nearby

  • St. Louis Union Station - 6 min walk - 0.6 km
  • Enterprise Center - 6 min walk - 0.6 km
  • City Museum - 6 min walk - 0.6 km
  • Busch Stadium - 14 min walk - 1.2 km
  • Gateway Arch - 2 min drive - 1.8 km

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • Lambert-St. Louis International Airport (STL) - 26 min drive

Restaurants

  • ‪Budweiser Kiel Club - ‬6 min walk
  • ‪City Museum Rooftop Cafe - ‬5 min walk
  • ‪Medina Grill - ‬5 min walk
  • ‪Idol Wolf - ‬1 min walk
  • ‪White Knight Diner - ‬4 min walk

About this property

21C Museum Hotel St Louis

Luxury hotel near Enterprise Center
Located close to St. Louis Union Station and Busch Stadium, 21C Museum Hotel St Louis provides a coffee shop/cafe, dry cleaning/laundry services and a bar. Treat yourself to a massage or other spa services. In addition to a gym and a business centre, guests can connect to free in-room WiFi.
You'll also enjoy the following perks during your stay:
  • An indoor pool
  • Cooked-to-order breakfast (surcharge), valet parking (surcharge) and a lift
  • A billiards/pool table, meeting rooms and ATM/banking services
  • Smoke-free property, a vending machine and a banquet hall
  • Guest reviews say great things the dining options, pool and helpful staff
Room features
All 104 rooms include comforts such as laptop-friendly workspaces and air conditioning, as well as perks such as free WiFi and desk chairs. Guest reviews highly rate the cleanliness rooms at the property.
More amenities include:
  • Free toiletries and hairdryers
  • Flat-screen TVs with premium channels
  • Wardrobes/cupboards, heating and daily housekeeping

Languages

English

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Grab bar in shower (89 centimetre high)
  • Handrails in stairways (91 centimetre high)
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk (91 centimetre high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Dressing gowns
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets are allowed for an extra charge of USD 100 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs only

Children and extra beds

Children are welcome
Rollaway/extra beds are not available.
Cots (infant beds) are not available

Payment types at the property

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Service fee: USD 5 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting

We should mention

Reservations are required for massage services; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

Frequently asked questions

Does 21C Museum Hotel St Louis have a pool?

Yes, this property has an indoor pool.

How much does it cost to stay at 21C Museum Hotel St Louis ?

As of 22 Aug 2025, prices found for a 1-night stay for 2 adults at 21C Museum Hotel St Louis on 31 Aug 2025 start from ฿4,955.07, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is 21C Museum Hotel St Louis pet-friendly?

Yes, dogs are allowed at this property. There's a fee of USD 100 per accommodation, per stay. Service animals are exempt from fees.

How much is parking at 21C Museum Hotel St Louis ?

Valet parking is available for USD 50 per day.

What time is check-in at 21C Museum Hotel St Louis ?

Check-in start time: 4:00 PM; check-in end time: 11:00 AM. Late check-in is available during limited hours.

What time is check-out at 21C Museum Hotel St Louis ?

Checkout is at 11:00 AM.

Where is 21C Museum Hotel St Louis located?

Located in Downtown West, this luxury hotel is within a 10-minute walk of Washington Avenue Historic District, City Museum, and Enterprise Center. St. Louis Union Station and America's Center Convention Complex are also within 15 minutes. 8th and Pine Station is 13 minutes by foot and Convention Center Station is 16 minutes.

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21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 950 out of 1316 reviews
Rating 8 - Good. 195 out of 1316 reviews
Rating 6 - Okay. 80 out of 1316 reviews
Rating 4 - Poor. 41 out of 1316 reviews
Rating 2 - Terrible. 50 out of 1316 reviews

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

10/10 Excellent

Angela

Liked: Cleanliness, staff & service, property conditions & facilities
Amazing hotel!
Stayed 1 night in Aug 2025

10/10 Excellent

Amanda

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful hotel and great food options. Gym and pool were great also.
Stayed 1 night in Aug 2025

10/10 Excellent

Patricia

Liked: Cleanliness, staff & service, property conditions & facilities
Fun place to stay. Museum on the 2nd floor was so much fun.
Stayed 1 night in Aug 2025

10/10 Excellent

Jeffrey

Liked: Cleanliness
Great place to stay.
Stayed 1 night in Jun 2025

10/10 Excellent

Frank

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great gym and pool.
Stayed 3 nights in Apr 2025

10/10 Excellent

rebecca

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was a great location
Stayed 1 night in Jun 2025

10/10 Excellent

Matthew

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Always enjoy staying at this hotel. Staff is always willing to lend a hand. Love the pool, art, and other amenities.
Stayed 2 nights in Jun 2025

10/10 Excellent

Lima Rose

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great stay
Stayed 1 night in Jun 2025

10/10 Excellent

Shamiyer

I loved my stay the room was perfect and very comfortable and clean
Stayed 1 night in Jul 2025

10/10 Excellent

Nicole

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This hotel was absolutely beautiful and so unique. The staff was so amazing and friendly, and the rooms were beautiful. We will definitely be repeat guests.
Stayed 3 nights in Jul 2025

10/10 Excellent

Will

Liked: Cleanliness, amenities, property conditions & facilities
Great place, decor, art, and people
Stayed 2 nights in Jun 2025

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Just stayed one night for a quick business trip but was impressed. Staff was excellent and room was really nice. Looks like they have a nice bar and restaurant in the lobby but didn't have a chance to check it out. I did hit the coffeeshop in the morning and it was really nice. I'll certainly be back next time I need to come to town.
Stayed 1 night in Aug 2025

10/10 Excellent

Jessica

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The hotel was very clean and easily accessible between restaurant, room, and galleries.
Stayed 1 night in Jun 2025

8/10 Good

Roger

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful building and the atmosphere was just relaxing and fun
Stayed 2 nights in Jun 2025

10/10 Excellent

Mike

Liked: Amenities
Museum is fabulous, lobby and room are terrific!
Stayed 1 night in Jul 2025

6/10 Okay

Veronica

Liked: Staff & service, property conditions & facilities
Nice hotel but the bathroom was dirty and the area was a little shady.
Stayed 1 night in Aug 2025

6/10 Okay

Catherine

Liked: Amenities
The ambience of the room was good. I didn’t like that they don’t have a microwave inside the room.
Stayed 1 night in Aug 2025

8/10 Good

Angela

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Wonderful hotel. I always enjoying seeking out and finding a 21C. The vibe was inviting and creative. Beautiful works of art. Loved the pool and gym/sauna/steam room area. We will stay again.
Stayed 1 night in Jul 2025

10/10 Excellent

Leslie

So different and classy
Stayed 1 night in Aug 2025

10/10 Excellent

Tabitha

Liked: Cleanliness, amenities, property conditions & facilities
Great value. Great restaurant. Great staff!
Stayed 2 nights in Jun 2025

8/10 Good

kayla

Liked: Amenities
Not a great area but a great hotel
Stayed 1 night in Jun 2025

10/10 Excellent

Korie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
very nice hotel felt worth the money
Stayed 1 night in Jun 2025

10/10 Excellent

Julie

Liked: Amenities
Everything about this hotel was magical! Food is fove star service people rooms. Saunna workout room and it's beautiful!
Stayed 2 nights in Jul 2025

10/10 Excellent

Trenicia

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved it! No complaints
Stayed 2 nights in Jul 2025

10/10 Excellent

Nicole

Liked: Cleanliness, property conditions & facilities
Thebhotel itself was beautiful akd clean. Parking, and the flooded streets made it miserable to get around directly around the hotel
Stayed 1 night in Jun 2025