Find hotels in Southwest Illinois, IL from ฿1,938
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Southwest Illinois
Pet friendly
Apartment
Condo
Family friendly
Cottage
Waterpark
Check prices for these dates
Tonight
13 Sep - 14 SepTomorrow
14 Sep - 15 SepNext weekend
18 Sep - 20 SepIn two weeks
25 Sep - 27 SepOur top choices for Southwest Illinois hotels
1. Best Western Plus Centralia Hotel & Suites
Best Western Plus Centralia Hotel & SuitesCentralia
Corey
฿4,594
฿5,144 total
includes taxes & fees
17 Sept - 18 Sept
2. Super 8 by Wyndham Okawville
Super 8 by Wyndham OkawvilleOkawville
Peter
฿2,107
฿2,233 total
includes taxes & fees
7 Oct - 8 Oct
3. Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. VernonMount Vernon
Kirstyn
฿3,668
฿4,137 total
includes taxes & fees
20 Sept - 21 Sept
4. Best Western U. S. Inn
Best Western U. S. InnNashville
Arilla
฿3,635
฿3,962 total
includes taxes & fees
1 Oct - 2 Oct
5. Holiday Inn Express Troy by IHG
Holiday Inn Express Troy by IHGTroy
Donald
฿3,636
฿4,035 total
includes taxes & fees
20 Sept - 21 Sept
6. Country Hearth Inn & Suites Edwardsville St. Louis
Country Hearth Inn & Suites Edwardsville St. LouisEdwardsville
les
฿4,263
฿4,902 total
includes taxes & fees
14 Sept - 15 Sept
7. Comfort Inn & Suites Greenville I-70
Comfort Inn & Suites Greenville I-70Greenville
Alan
฿3,242
฿3,598 total
includes taxes & fees
20 Sept - 21 Sept
8. SureStay Hotel by Best Western Whittington Rend Lake
SureStay Hotel by Best Western Whittington Rend LakeWhittington
MARK
฿2,677
฿2,971 total
includes taxes & fees
20 Sept - 21 Sept
9. Fairfield Inn & Suites by Marriott O'Fallon, IL
Fairfield Inn & Suites by Marriott O'Fallon, ILO'Fallon
Mohamad
฿4,580
฿5,266 total
includes taxes & fees
27 Sept - 28 Sept
10. Super 8 by Wyndham Troy IL/St. Louis Area
Super 8 by Wyndham Troy IL/St. Louis AreaTroy
Esmeralda
฿2,247
฿2,494 total
includes taxes & fees
20 Sept - 21 Sept
11. Best Western Plus MidAmerica Hotel
Best Western Plus MidAmerica HotelMascoutah
Justin
฿3,621
฿4,127 total
includes taxes & fees
27 Sept - 28 Sept
12. Seasons Inn & Suites Highland
Seasons Inn & Suites HighlandHighland
Patricia
฿2,967
฿3,293 total
includes taxes & fees
1 Oct - 2 Oct
13. Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites St. Louis O'Fallon, ILO'Fallon
KEVIN
฿3,503
฿4,063 total
includes taxes & fees
20 Sept - 21 Sept
14. Quality Inn Mount Vernon, IL
Quality Inn Mount Vernon, ILMount Vernon
Matthew
฿2,499
฿2,839 total
includes taxes & fees
20 Sept - 21 Sept
15. Holiday Inn Express & Suites Mount Vernon by IHG
Holiday Inn Express & Suites Mount Vernon by IHGMount Vernon
John
฿3,669
฿4,137 total
includes taxes & fees
11 Oct - 12 Oct
16. Drury Inn & Suites Marion
Drury Inn & Suites MarionMarion
Suzanne
฿3,007
฿3,608 total
includes taxes & fees
20 Sept - 21 Sept
17. Comfort Suites Mount Vernon
Comfort Suites Mount VernonMount Vernon
James
฿3,925
฿4,422 total
includes taxes & fees
4 Oct - 5 Oct
18. Hampton Inn O'Fallon
Hampton Inn O'FallonO'Fallon
Mary
฿3,632
฿4,212 total
includes taxes & fees
20 Sept - 21 Sept
19. Days Inn by Wyndham Mount Vernon
Days Inn by Wyndham Mount VernonMount Vernon
Asa
฿2,388
฿2,716 total
includes taxes & fees
20 Sept - 21 Sept
20. Super 8 by Wyndham Mt. Vernon IL
Super 8 by Wyndham Mt. Vernon ILMount Vernon
Matthew W,
฿2,413
฿2,744 total
includes taxes & fees
14 Sept - 15 Sept
Stay near popular Southwest Illinois attractions
World Wide Technology Raceway
9.0/10 (2 reviews)
Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
O'Fallon Family Sports Park
8.6/10 (137 reviews)
Explore the great outdoors at O'Fallon Family Sports Park, a lovely green space in O'Fallon. Visit the shops and top-notch restaurants in this family-friendly area.
DuQuoin State Fairgrounds
8.2/10 (95 reviews)
Catch an event at DuQuoin State Fairgrounds during your trip to Du Quoin. Experience the area's festivals and live music.
Learn more about Southwest Illinois
Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.
See all hotels in Southwest Illinois
Top Southwest Illinois Hotel Reviews
Drury Plaza Hotel Mt. Vernon
10/10 Excellent
"The room was clean, the beds were cozy,the food and drinks were excellent, the pool and hot tub was amazing, and the staff was more than friendly! I love the Drury!"
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
10/10 Excellent
"Clean room, good breakfast"
Quality Inn & Suites near St. Louis and I-255
8/10 Good
"The property is older and could use some updating. It was pretty clean. I worried a little about the location; however we didn’t have any issues at all. It was easy to get to the baseball game. The staff at the hotel was friendly."
Drury Inn & Suites St. Louis Fairview Heights
10/10 Excellent
"The amenities where excellent and offered more then other places offer. The staff were kind d and friendly. The rooms where clean, comfortable, and up to what you wa t feom a hotel stay.I would stay there again."
Motel 6 Caseyville, IL - Caseyville Il
8/10 Good
"Average"
Comfort Inn Edwardsville - St. Louis
10/10 Excellent
"A very nice place to stay. Breakfast was amazing."
Comfort Suites Fairview Heights - St. Louis
8/10 Good
"There was a smell in our room that was very strong. Other than that it was clean."
Comfort Suites Mount Vernon
8/10 Good
"Mmm"
The Principal Hotel
8/10 Good
"This place was immaculately clean - maybe too clean as we had a kind of chemical cleaner smell to our room. That’s actually my only real complaint about the property itself. It’s cute, well maintained, easy to park, and convenient. We did not find the staff to be particularly friendly or helpful, though. The girl at check in seemed a little annoyed at having to deal with us, and didn’t give any information -just gave us the keys. The next morning I came down looking for water. There’s a small grab and grow breakfast of fruit and cereal bars which was really nice. But when I was looking for something, the woman at the desk was talking loudly on a personal cell phone call and didn’t bother to acknowledge me at all. After five minutes, I just gave up. We’d definitely stay here again. We loved the concept and the big clean rooms! Just wish there wasn’t a cleaner smell or an unprofessional staff."
More cheap stays in Southwest Illinois
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
฿1,686
฿1,938 total
20 Sept - 21 Sept
includes taxes & fees
Americas Best Value Inn Collinsville St. Louis
552 Ramada Blvd Collinsville IL
฿1,739
฿2,000 total
11 Oct - 12 Oct
includes taxes & fees
Super 8 by Wyndham Collinsville St. Louis
2 Gateway Dr Collinsville IL
฿1,933
฿2,223 total
14 Sept - 15 Sept
includes taxes & fees
7/10 Good! (1,005 reviews)
Super 8 by Wyndham Mt. Vernon IL
401 S 44th St Mount Vernon IL
฿2,413
฿2,744 total
14 Sept - 15 Sept
includes taxes & fees
Comfort Inn Edwardsville - St. Louis
3080 S State Route 157 Edwardsville IL
฿3,034
฿3,488 total
23 Sept - 24 Sept
includes taxes & fees
8.4/10 Very good! (936 reviews)
Baymont by Wyndham Marion
2608 W Main St Marion IL
฿2,983
฿3,579 total
20 Sept - 21 Sept
includes taxes & fees
