A calm lake surrounded by trees and vegetation.

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30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

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Our top choices for Southwest Illinois hotels

A hotel kitchen with wooden cabinets, a coffee station, and a dining area with tables and chairs.

1. Best Western U. S. Inn

Best Western U. S. Inn
2.5 star property
Nashville
8.6 out of 10, Excellent, (459 reviews)
"Worked well for our short stay."
United States
Steven
The price is ฿4,053
฿4,417 total
includes taxes & fees
2 Nov - 3 Nov
Best Western U. S. Inn
A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

2. Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
2.5 star property
Centralia
9.6 out of 10, Exceptional, (685 reviews)
"We stayed here with 2 adults and 3 kids and it was perfect. We highly recommend staying here"
United States
Jeremy
The price is ฿4,697
฿5,259 total
includes taxes & fees
29 Oct - 30 Oct
Best Western Plus Centralia Hotel & Suites
A hotel with a covered entrance, stone pillars, and a modern design.

3. Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
2.5 star property
Mount Vernon
8.8 out of 10, Excellent, (1,000 reviews)
"Great spacious room. Breakfast was awesome and the helper was outstanding! Great food and coffee."
United States
Doug
The price is ฿3,849
฿4,339 total
includes taxes & fees
31 Oct - 1 Nov
Holiday Inn Express & Suites Mount Vernon by IHG
A bar area with a long counter, multiple chairs, and hanging light fixtures.

4. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.5 star property
Mount Vernon
9.8 out of 10, Exceptional, (1,851 reviews)
"Loved the beds, and lobby bar/resturant."
United States
Richard
The price is ฿3,750
฿4,230 total
includes taxes & fees
1 Nov - 2 Nov
Drury Plaza Hotel Mt. Vernon
A hotel lobby with a reception desk, seating area, and a large screen TV.

5. Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1,090 reviews)
"Great bathroom"
United States
Bruce and Robin
The price is ฿3,974
฿4,478 total
includes taxes & fees
15 Nov - 16 Nov
Comfort Suites Mount Vernon
A hotel lobby with a large sofa, armchairs, a Christmas tree, and a patterned carpet.

6. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
3.0 star property
Mount Vernon
8.8 out of 10, Excellent, (729 reviews)
"Beautiful property very clean when you enter the lobby is very impressive in the staff was very helpful. Our room was clean in the morning. Breakfast was great."
United States
Susan
The price is ฿3,388
฿3,828 total
includes taxes & fees
15 Nov - 16 Nov
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
A modern indoor pool area with a blue ceiling, large windows, and a pool with a metal ladder.

7. Hampton Inn O'Fallon

Hampton Inn O'Fallon
2.5 star property
O'Fallon
9.2 out of 10, Wonderful, (885 reviews)
"Really nice"
United States
Edmond
The price is ฿3,849
฿4,464 total
includes taxes & fees
8 Nov - 9 Nov
Hampton Inn O'Fallon
An outdoor seating area with a fire feature, cushioned seating, and a bar area.

8. TownePlace Suites by Marriott St. Louis O'Fallon

TownePlace Suites by Marriott St. Louis O'Fallon
3.0 star property
O'Fallon
9.0 out of 10, Wonderful, (159 reviews)
"Conditioner would not pump anything out and even trying to take it out of the holster was impossible. And the pool was freezing cold. I thought it was a heated pool. Other than that, everything else was excellent."
United States
Bethany
The price is ฿4,426
฿5,134 total
includes taxes & fees
15 Nov - 16 Nov
TownePlace Suites by Marriott St. Louis O'Fallon
A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.

9. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (1,004 reviews)
"Very clean and everything was perfect!"
United States
Tad
The price is ฿2,737
฿3,037 total
includes taxes & fees
3 Nov - 4 Nov
SureStay Hotel by Best Western Whittington Rend Lake
A modern kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave. There are red chairs and a table in the dining area.

10. Quality Inn Mount Vernon, IL

Quality Inn Mount Vernon, IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (720 reviews)
"Clean rooms, complimentary breakfast, great value."
United States
Ryan
The price is ฿2,433
฿2,768 total
includes taxes & fees
8 Nov - 9 Nov
Quality Inn Mount Vernon, IL
An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.

11. DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
4.0 star property
Mount Vernon
8.4 out of 10, Very good, (908 reviews)
"Nice clean and great staff"
United States
Kenneth
The price is ฿4,010
฿4,518 total
includes taxes & fees
30 Oct - 31 Oct
DoubleTree by Hilton Mt. Vernon
A modern dining area with multiple tables and chairs, a kitchen area with appliances, and a ceiling with recessed lighting and a circular light fixture.

12. Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel
2.5 star property
Mascoutah
9.0 out of 10, Wonderful, (1,001 reviews)
"Staff was wonderful and the breakfast was good."
United States
Alice
The price is ฿3,404
฿3,880 total
includes taxes & fees
1 Nov - 2 Nov
Best Western Plus MidAmerica Hotel
A buffet with various food items, including omelets and other dishes, arranged on a counter with a patterned tile backsplash.

13. Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG
2.5 star property
Sparta
9.2 out of 10, Wonderful, (434 reviews)
"Clean property and friendly staff"
United States
Jo Ann
The price is ฿3,379
฿3,750 total
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express Hotel & Suites Sparta by IHG
An indoor swimming pool area with multiple lanes, lounge chairs, and a small seating area.

14. Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL
3.0 star property
O'Fallon
9.6 out of 10, Exceptional, (1,001 reviews)
"Staff was very friendly"
United States
Karissa
The price is ฿3,446
฿3,997 total
includes taxes & fees
2 Nov - 3 Nov
Drury Inn & Suites St. Louis O'Fallon, IL
A Comfort Inn & Suites hotel with a covered entrance, multiple floors, and a landscaped front yard.

15. Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57
2.5 star property
Marion
9.4 out of 10, Exceptional, (1,002 reviews)
"Clean and comfortable room. Breakfast options were very good!"
United States
Suzan
The price is ฿3,678
฿4,413 total
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn & Suites Marion I-57
An outdoor patio with tables and chairs, a brick building, and a parking lot in the background.

16. Fairfield Inn & Suites by Marriott O'Fallon, IL

Fairfield Inn & Suites by Marriott O'Fallon, IL
3.0 star property
O'Fallon
9.2 out of 10, Wonderful, (371 reviews)
"Great hotel"
United States
Mohamad
The price is ฿4,682
฿5,384 total
includes taxes & fees
11 Nov - 12 Nov
Fairfield Inn & Suites by Marriott O'Fallon, IL
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

17. Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (1,013 reviews)
"Everything was clean, nice hotel"
United States
Leslie
The price is ฿2,467
฿2,805 total
includes taxes & fees
1 Nov - 2 Nov
Super 8 by Wyndham Mt. Vernon IL
A modern living room with a fireplace, a bookshelf, a large wall clock, and a cozy seating area.

18. Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL
2.5 star property
Marion
8.6 out of 10, Excellent, (1,001 reviews)
"This is an excellent hotel to stay at. Updated, easy parking, staff is very friendly, breakfast is great, will stay at this hotel again."
United States
Lisa
The price is ฿3,332
฿3,997 total
includes taxes & fees
22 Nov - 23 Nov
Country Inn & Suites by Radisson, Marion, IL
An outdoor patio with stone fire pit, colorful striped sofas, and blue chairs.

19. Home2 Suites by Hilton Carbondale

Home2 Suites by Hilton Carbondale
3.0 star property
Carbondale
8.8 out of 10, Excellent, (598 reviews)
"Location is steps away from main drag and SIU campus."
United States
Margaret
The price is ฿4,278
฿4,919 total
includes taxes & fees
25 Nov - 26 Nov
Home2 Suites by Hilton Carbondale
A restaurant with multiple tables and booths, large windows, and a modern interior design.

20. The Principal Hotel

The Principal Hotel
3.5 star property
Columbia
9.6 out of 10, Exceptional, (452 reviews)
"It was just a beautiful, comfortable place to stay."
United States
Jeffrey
The price is ฿3,315
฿3,679 total
includes taxes & fees
29 Oct - 30 Oct
The Principal Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Southwest Illinois attractions

O'Fallon Family Sports Park

8.6/10 (137 reviews)
Explore the great outdoors at O'Fallon Family Sports Park, a lovely green space in O'Fallon. Visit the shops and top-notch restaurants in this family-friendly area.
See properties

Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

See all hotels in Southwest Illinois
A tall, cylindrical structure with a red and white striped pattern and a label reading "Brock's Old Original Catsup."
Photo by throwingsofas
Open Photo by throwingsofas

Top Southwest Illinois Hotel Reviews

Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL

8/10 Good
"It was pretty good. Bed’s not comfortable ! Room was not nice and really clean! Breakfast was good, not tons of choices. Tub had a Nasty crack in it near the drain . You could bathe a kid in it without worrying about them!. I have stayed in better Country Inn & Suites, which is why I chose the “Brand”. But overall, it was a good stay!"
Jodi 1-night trip
Posted 3 hours ago
Country Inn & Suites by Radisson, Marion, IL