Southeast Missouri Travel Guide

Tourist Guide

Southeast Missouri
Southeast Missouri
Southeast Missouri
Photo by Jessica Richter
Photo by Jessica Richter
Photo by Jessica Richter
Photo by Jessica Richter
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St Farmington MO
The price is ฿1,643 per night from 2 Jan to 3 Jan
฿1,643
฿1,871 total
2 Jan - 3 Jan 2026
includes taxes & fees
Stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking and an outdoor pool. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,003 reviews)
Yes

Reviewed on 21 Dec 2025

Baymont Inn and Suites by Wyndham Farmington, MO
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is ฿2,799 per night from 29 Dec to 30 Dec
฿2,799
฿3,158 total
29 Dec - 30 Dec
includes taxes & fees
Stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,007 reviews)
The room was great. Very clean and the bed was comfortable.

Reviewed on 21 Dec 2025

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is ฿2,996 per night from 29 Dec to 30 Dec
฿2,996
฿3,379 total
29 Dec - 30 Dec
includes taxes & fees
Stay at this business-friendly hotel in Cape Girardeau. Enjoy free Wi-Fi, free parking and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and ...
9.4/10 Exceptional! (474 reviews)
The room was clean and the mattress was extremely comfortable

Reviewed on 14 Dec 2025

The Riverview
See all 620 properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

2 out of 5
7555 State Hwy Y French Village MO
Stay at this cabin in French Village. Enjoy free parking, patios and climate control.
9.8/10 Exceptional! (44 reviews)
The cabin was cozy and very peaceful such a good experience

Reviewed on 11 Nov 2025

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Sam A Baker State Park

Sam A Baker State Park

2 out of 5
5732 State Hwy Missouri 143 Patterson MO
Stay at this cabin in Patterson. Enjoy free parking, a picnic area and furnished patios. Popular attraction Sam A. Baker State Park is located nearby.
9.2/10 Wonderful! (5 reviews)
We stayed two nights and we loved it. The property grounds and cabins are well maintained we will be back

Reviewed on 5 Oct 2025

Sam A Baker State Park
Johnson's Shut-ins State Park

Johnson's Shut-ins State Park

3 out of 5
148 Taum Sauk Trail Middle Brook MO
Stay at this cabin in Middle Brook. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Popular attractions Johnson's Shut-ins State Park and Taum Sauk ...
10/10 Exceptional! (1 review)
These newer cabins are clean and have everything you need. Highly recommend!

Reviewed on 5 Nov 2025

Johnson's Shut-ins State Park
See all properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Elephant Rocks State Park

Elephant Rocks State Park

You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.

Elephant Rocks State Park
Lake Wappapello

Lake Wappapello

Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.

Lake Wappapello

Southeast Missouri State University

Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.

Southeast Missouri State University

Century Casino Caruthersville

Why not try your luck with a visit to Century Casino Caruthersville during your visit to Caruthersville? While in this family-friendly area, you can enjoy the restaurants.

Century Casino Caruthersville

Isle Casino Cape Girardeau

Why not roll the dice with a visit to Isle Casino Cape Girardeau during your time in Cape Girardeau? While in this family-friendly area, you can savour the top-notch restaurants.

Isle Casino Cape Girardeau

Bonne Terre Mine

Commune with nature and explore the great outdoors at Bonne Terre Mine during your travels in Bonne Terre. You can seek out the golf courses while in the area.

Bonne Terre Mine

Things to do

Castle Entrance

History Tour of Pythian Castle in Springfield Missouri

฿405
per adult
90% of travellers recommend
History Tour of Pythian Castle in Springfield Missouri
Pythian Castle

Night Ghost Tour of Pythian Castle in Springfield Missouri

฿571
per adult
100% of travellers recommend
Night Ghost Tour of Pythian Castle in Springfield Missouri
Ozark Craft Beverage - Brewery Tour

Ozark Craft Beverage - Brewery Tour

฿4,928
per adult
Ozark Craft Beverage - Brewery Tour
See all activities in Southeast Missouri

Cities near Southeast Missouri

Photo by Karissa Krull

Farmington