Photo by Bill Dillard
Find hotels in Southeast Missouri, MO from ฿1,864
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Our top choices for Southeast Missouri hotels
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,001 reviews)
"Breakfast was good,pool hot tub excellent "
Janica
The price is ฿3,614
฿4,155 total
includes taxes & fees
25 May - 26 May
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
"Room was very clean. Breakfast was good with several options. Would recommend staying here."
Linda
The price is ฿3,582
฿4,041 total
includes taxes & fees
31 May - 1 Jun
Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (903 reviews)
"Nice overnight stop over"
Douglas
The price is ฿3,419
฿3,863 total
includes taxes & fees
7 Jun - 8 Jun
Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (562 reviews)
"Perfect nights stay!! "
Amanda
The price is ฿3,311
฿3,749 total
includes taxes & fees
31 May - 1 Jun
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (768 reviews)
"Nice hotel"
Jeff
The price is ฿3,017
฿3,265 total
includes taxes & fees
24 May - 25 May
The Farmstead Hotel
The Farmstead HotelCaruthersville
8.6 out of 10, Excellent, (552 reviews)
"felt safe stayed only in hotel was clean and quiet and felt safe."
Michael
The price is ฿3,093
฿3,518 total
includes taxes & fees
31 May - 1 Jun
Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MOPoplar Bluff
8.0 out of 10, Very good, (1,001 reviews)
"The staff was great"
Jasmine
The price is ฿2,442
฿2,735 total
includes taxes & fees
24 May - 25 May
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,000 reviews)
"We found this property to be everything someone would hope for in an overnight stay away from home."
Richard
The price is ฿3,256
฿3,673 total
includes taxes & fees
14 Jun - 15 Jun
Super 8 by Wyndham Perryville
Super 8 by Wyndham PerryvillePerryville
8.4 out of 10, Very good, (999 reviews)
"Enjoyed our stay "
Cynthia
The price is ฿2,242
฿2,566 total
includes taxes & fees
27 May - 28 May
Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (844 reviews)
"Nice quiet overnight stay."
Tammy
The price is ฿3,056
฿3,422 total
includes taxes & fees
7 Jun - 8 Jun
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,000 reviews)
"Clean room, friendly staff, good breakfast and dinner variety,large open parking, clean pool and exercise room. All around great stay.
"
Jeremy
The price is ฿2,605
฿2,754 total
includes taxes & fees
25 May - 26 May
Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.6 out of 10, Excellent, (355 reviews)
"We stayed one night. For a small town, it's a decent Inn to stay. Could there be updates to the rooms, yes, but overall it was okay. Will we stay again? Unsure."
Wanda
The price is ฿3,106
฿3,367 total
includes taxes & fees
26 May - 27 May
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,000 reviews)
"Excellent layover stay"
Wesley H.
The price is ฿2,344
฿2,645 total
includes taxes & fees
7 Jun - 8 Jun
Madison Inn Lodge
Madison Inn LodgeFredericktown
7.6 out of 10, Good, (301 reviews)
"Rooms were clean! Beds were comfortable, and the staff were very accommodating."
Ashley
The price is ฿2,850
฿3,113 total
includes taxes & fees
26 May - 27 May
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (462 reviews)
"Clean rooms, friendly staff and convenient location."
Mark
The price is ฿3,289
฿3,724 total
includes taxes & fees
21 Jun - 22 Jun
The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (575 reviews)
"I ALWAYS stay here when I come to Cape! Wonderful, great place!"
Audra
The price is ฿4,308
฿4,860 total
includes taxes & fees
25 May - 26 May
Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (80 reviews)
"The breakfast was good, the service was good, and the staff was very friendly"
Angela
The price is ฿3,582
฿4,056 total
includes taxes & fees
28 May - 29 May
Current River Inn
Current River InnVan Buren
8.2 out of 10, Very good, (175 reviews)
"This was the cutest little place to stay. The people are friendly, room was clean, and it was safe. I would stay here again. "
Jennifer
The price is ฿3,546
฿3,837 total
includes taxes & fees
28 May - 29 May
Super 8 by Wyndham Potosi
Super 8 by Wyndham PotosiPotosi
7.0 out of 10, Good, (398 reviews)
"My husband and I just bought land recently and this was the closest to us. Very quiet , looks like they are renovating, but it didnt inconvenience at all. Hot showers, clean towels ,comfortable bed and great smart tv! Loved the new carpet!We will be back ! "
Wesley
The price is ฿1,922
฿2,100 total
includes taxes & fees
26 May - 27 May
Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very good, (1,014 reviews)
"Breakfast was fresh and the room was clean. It's a good place to stay. Friendly staff. "
Tabitha
The price is ฿2,946
฿3,358 total
includes taxes & fees
21 Jun - 22 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Southeast Missouri
Cabin
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (70 reviews)
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Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from K Bridge Recreation Area to Clearwater Lake.
Photo by Bill Dillard
Open Photo by Bill Dillard
More cheap stays in Southeast Missouri
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is ฿1,935 per night from 14 Jun to 15 Jun
฿1,935
฿2,107 total
14 Jun - 15 Jun
includes taxes & fees
8/10 Very Good! (1,003 reviews)
