Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers comfort in a rural setting with free breakfast and an indoor pool. Relax at the onsite spa and sun loungers by the pool. Dry cleaning, laundry services, and luggage storage are available, with highly praised staff.
Located in Cape Girardeau, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is in a rural area and near the airport. The area's natural beauty can be seen at Shawnee National Forest and Mississippi River. Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are also worth visiting. Visit our Cape Girardeau travel guide
3253 William Street, Cape Girardeau, MO, 63701
What's nearby
Southeast Missouri State University
6 min drive - 6.3 km
Saint Francis Medical Center
6 min walk - 0.6 km
Riverfront Park
6 min drive - 7.7 km
Isle Casino Cape Girardeau
8 min drive - 9.1 km
Show Me Center
9 min drive - 9.1 km
Getting around
Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
10 min drive
Restaurants
Chick-fil-A
7 min walk
Rhodes
20 min walk
McDonald's
10 min walk
White Castle
10 min walk
Wings Etc.
9 min walk
About this property
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Hotel near Shawnee National Forest
You can look forward to free breakfast, dry cleaning/laundry services and a gym at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG. Take some time to relax at the on-site spa. In addition to a business centre, guests can connect to free in-room WiFi.
You'll also enjoy perks such as:
Swimming pool, along with sunloungers
Free self-parking
An indoor pool, a banquet hall and laundry services
Luggage storage, smoke-free property and 1 meeting room
Guest reviews give top marks for the breakfast and helpful staff
Room features
All 102 rooms include comforts, such as premium bedding and pillow menus, in addition to thoughtful touches, such as laptop-friendly workspaces and air conditioning. Guest reviews speak positively of the cleanliness rooms at the property.
Other amenities include:
Pillowtop mattresses and down duvets
Bathrooms with free toiletries and hairdryers
52-inch flat-screen TVs with premium channels
Separate sitting areas, mini fridges and microwaves
Available in all rooms: Free WiFi and wired internet
Available in some public areas: Free WiFi and wired internet
Parking and transport
Free self parking on site
Limited on-site self parking
Wheelchair-accessible parking available
Food and drink
Free breakfast available
Things to do
Full-service spa
Gym
Indoor pool
Family friendly
In-room microwave
Indoor pool
Laundry facilities
Mini-fridge
Conveniences
24-hour front desk
Free newspapers in lobby
Laundry facilities
Luggage storage
Safe at front desk
Vending machine
Guest services
Dry cleaning/laundry service
Housekeeping (daily)
Porter/bellhop
Business services
118 square feet of conference space
Business centre
Meeting room
Outdoors
Pool loungers
Accessibility
If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
Assistive listening devices
Braille/raised signage
Visual fire alarm
Well-lit path to entrance
Wheelchair accessible (may have limitations)
Wheelchair-accessible parking
Wheelchair-accessible path of travel
Wheelchair-accessible path to lift
More
1 building
4 floors
Banquet hall
Smoke-free property
Room amenities
Bedroom
Down comforter
Pillow menu
Pillowtop mattress
Premium bedding
Bathroom
Free toiletries
Hair dryer
Private bathroom
Shampoo
Soap
Toilet paper
Towels provided
Entertainment
52-inch flat-screen TV with premium cable channels
Food and drink
Coffee/tea maker
Microwave
Mini-fridge
More
Air conditioning (climate-controlled)
Connecting rooms available
Desk
Free local calls
Iron/ironing board
Laptop workspace
Phone
Safe
Separate sitting area
Policies
Check-in
Check-in start time: 3:00 PM; check-in end time: anytime
Contactless check-in and check-out are available
Minimum check-in age - 21
Check-out
Check-out before 11 AM
Contactless check-out
Special check-in instructions
Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools
Access methods
Staffed front desk
Pets
Pets not allowed
Children and extra beds
Children are welcome
Cots (infant beds) are not available
Payment types at the property
Important information
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a fire extinguisher and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
We should mention
Pool access available from 8 AM to 11 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)
Property is also known as
Holiday Inn Express Cape Girardeau I-55
Holiday Inn Express Hotel Cape Girardeau I-55
Holiday Inn Hotel I-55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Inn Express Cape Girarau I55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG
Frequently asked questions
Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a pool?
Yes, this property has an indoor pool. Pool access is from 8 AM to 11 PM.
How much does it cost to stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?
As of 11 Mar 2026, prices found for a 1-night stay for 2 adults at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG on 29 Mar 2026 start from ฿3,129, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
Is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG pet-friendly?
No, pets are not allowed at this property.
How much is parking at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?
Self-parking is free at this property.
What time is check-in at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?
Check-in start time: 3:00 PM; check-in end time: anytime.
What time is check-out at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?
Checkout is at 11 AM.
Where is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG located?
Situated near the airport, this spa hotel is 0.6 mi (1 km) from Saint Francis Medical Center and within 3 miles (5 km) of Saint Francis Healthcare System and Southeast Missouri Hospital. Cape Splash Family Aquatic Center is 3 mi (4.9 km) away.
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Reviews
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews
9.4
Exceptional
All reviews shown are from real guest experiences. Only travellers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly.
Brian
Stayed 1 night in Dec 2025
10/10 Excellent
Erik
30 Nov 2025
Liked: Cleanliness, staff & service, amenities
The room was clean, the staff were friendly, and they gave out free cookies in the evening, not just breakfast in the morning.
Fast, very friendly desk service. We were allowed to check in a little early, a big plus since we arrived at 2 for a wedding at 3!! We got down for breakfast 30 minutes before the end of closing and it was evident. But the pancakes were great! Thanks for everyone's service!
Our stay was wonderful. The rooms are so nice. Bed was comfortable. The jaccuzi tub is excellent. The free breakfast was lovely. Even had healthy options with turkey sausage and egg white omelets. Delicious.
This was our 2nd time staying at this hotel while traveling. Hotel is very well maintained, easy access off interstate and has a number of restaurants and gas stations for your convenience.