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6 Nov - 8 Nov
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13 Nov - 15 Nov

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Our top choices for Santo Domingo hotels

A courtyard with a paved walkway, a metal gate with "CIUDAD DE MÉXICO" sign, and a dog on the right.

1. UNAM CIUDAD DE MEXICO CASA DE HUESPEDES

UNAM CIUDAD DE MEXICO CASA DE HUESPEDES
3.0 star property
Santo Domingo
The price is ฿2,262
฿2,704 total
includes taxes & fees
3 Nov - 4 Nov
UNAM CIUDAD DE MEXICO CASA DE HUESPEDES
A modern hotel room with a large bed, a sofa, a desk, and a view of the city.

2. Krystal Grand Suites Insurgentes

Krystal Grand Suites Insurgentes
4.0 star property
3.4 km from Santo Domingo
9.2 out of 10, Wonderful, (1,574 reviews)
"One of our favorite spots to stay when we’re in a quick trip to Mexico City"
United States
Gloria
The price is ฿4,422
฿5,284 total
includes taxes & fees
15 Nov - 16 Nov
Krystal Grand Suites Insurgentes
A modern lobby with a central staircase, seating areas, and a glass elevator.

3. Royal Pedregal Hotel

Royal Pedregal Hotel
4.0 star property
4.6 km from Santo Domingo
9.2 out of 10, Wonderful, (2,264 reviews)
"Excelente hotel"
Mexico
Jorge Enrique
The price is ฿3,686
฿4,404 total
includes taxes & fees
3 Nov - 4 Nov
Royal Pedregal Hotel
A reception area with a modern design, featuring a white reception desk, a potted plant, and a shelf with various decorative items.

4. Fiesta Inn Periferico Sur

Fiesta Inn Periferico Sur
3.5 star property
Coyoacan, 2.9 km from Santo Domingo
9.0 out of 10, Wonderful, (1,367 reviews)
"Excelente hotel"
Mexico
Sofia
The price is ฿3,513
฿4,198 total
includes taxes & fees
17 Nov - 18 Nov
Fiesta Inn Periferico Sur
A modern hotel room with a bed, a desk, a chair, a TV, and a bathroom with a mirror and sink.

5. Holiday Inn Mexico City - Plaza Universidad by IHG

Holiday Inn Mexico City - Plaza Universidad by IHG
3.5 star property
Benito Juarez, 4.3 km from Santo Domingo
9.4 out of 10, Exceptional, (1,003 reviews)
"All was great"
Mexico
Alejandro
The price is ฿4,459
฿5,329 total
includes taxes & fees
29 Nov - 30 Nov
Holiday Inn Mexico City - Plaza Universidad by IHG
A rooftop pool area with sun loungers and umbrellas, a wooden deck, and a city skyline in the background.

6. Galeria Plaza San Jeronimo

Galeria Plaza San Jeronimo
4.0 star property
5.1 km from Santo Domingo
9.4 out of 10, Exceptional, (1,098 reviews)
"Excellent service and room, and pool"
Mexico
Jorge Carlos
The price is ฿4,489
฿5,364 total
includes taxes & fees
1 Dec - 2 Dec
Galeria Plaza San Jeronimo
A spacious lobby with a high ceiling, multiple seating areas, and indoor plants.

7. Radisson Paraiso Hotel Mexico City

Radisson Paraiso Hotel Mexico City
4.0 star property
3.9 km from Santo Domingo
9.0 out of 10, Wonderful, (1,071 reviews)
"Mas bells boy solonhay uno"
Mexico
Adolfo
The price is ฿3,959
฿4,731 total
includes taxes & fees
26 Nov - 27 Nov
Radisson Paraiso Hotel Mexico City
A modern lobby with a curved staircase, seating areas, and a reception desk.

8. Camino Real Pedregal Mexico

Camino Real Pedregal Mexico
4.0 star property
6.1 km from Santo Domingo
9.0 out of 10, Wonderful, (1,851 reviews)
"Location is great and service/food too. I love to stay here."
United States
Bruno
The price is ฿4,020
฿4,803 total
includes taxes & fees
28 Nov - 29 Nov
Camino Real Pedregal Mexico
A modern hotel room with a flat-screen TV, a desk, a comfortable sofa, and a bed with patterned bedding.

9. Econo Express Hotel by Nokte Inn

Econo Express Hotel by Nokte Inn
3.5 star property
Benito Juarez, 6.4 km from Santo Domingo
9.0 out of 10, Wonderful, (1,985 reviews)
"I really enjoyed my stay."
United States
Carlina Moses
The price is ฿1,724
฿2,061 total
includes taxes & fees
10 Nov - 11 Nov
Econo Express Hotel by Nokte Inn
A modern hotel building with a prominent sign reading "Hotel Hara".

10. Hotel Harare

Hotel Harare
3.0 star property
Benito Juarez, 7.1 km from Santo Domingo
9.2 out of 10, Wonderful, (776 reviews)
"Hotel Harare is very convenient for a weekend trip. The staff was very accommodating when I added guests to my group."
United States
Adriana
The price is ฿1,403
฿1,676 total
includes taxes & fees
3 Nov - 4 Nov
Hotel Harare
A serene indoor garden with a waterfall, a stone pathway, and a staircase leading to an upper level.

11. El Diplomatico Hotel

El Diplomatico Hotel
4.0 star property
Benito Juarez, 5.9 km from Santo Domingo
9.0 out of 10, Wonderful, (1,588 reviews)
"Great location"
United States
DULCE
The price is ฿2,612
฿3,121 total
includes taxes & fees
6 Nov - 7 Nov
El Diplomatico Hotel
A hot tub with a cityscape view at sunset.

12. Holiday Inn Express Mexico Aeropuerto by IHG

Holiday Inn Express Mexico Aeropuerto by IHG
3.0 star property
10.6 km from Santo Domingo
9.4 out of 10, Exceptional, (1,948 reviews)
"Todo excelente"
Mexico
Alan
The price is ฿3,485
฿4,170 total
includes taxes & fees
5 Nov - 6 Nov
Holiday Inn Express Mexico Aeropuerto by IHG
A hotel room with a bed, a large mirror, a sink, and a decorative wall.

13. Hotel Amala

Hotel Amala
3.5 star property
7.6 km from Santo Domingo
8.8 out of 10, Excellent, (384 reviews)
"Clean room , walking distance to food and Cuemanco trajinera rides."
United States
Michel
The price is ฿1,327
฿1,586 total
includes taxes & fees
8 Nov - 9 Nov
Hotel Amala
A hotel room with two beds, a desk, a chair, a TV, and a window with a city view.

14. Fiesta Inn Insurgentes Sur

Fiesta Inn Insurgentes Sur
3.5 star property
4.4 km from Santo Domingo
9.4 out of 10, Exceptional, (1,012 reviews)
"Friendly staff, clean spacious room, located in a quiet area. I had a really nice stay."
United States
Luis Miguel
The price is ฿4,053
฿4,844 total
includes taxes & fees
7 Nov - 8 Nov
Fiesta Inn Insurgentes Sur
A room with a blue sofa, a lamp, framed pictures on the wall, and a mirror reflecting the room.

15. Hotel Real Azteca

Hotel Real Azteca
2.5 star property
3.4 km from Santo Domingo
8.0 out of 10, Very good, (35 reviews)
"Clean place, staff very nice. Great place to stay if going to the stadium. Downside is you have to wait for someone to open the gate every time you go out."
United States
felix
The price is ฿3,326
฿3,975 total
includes taxes & fees
3 Nov - 4 Nov
Hotel Real Azteca
A modern lobby with a polished floor, a reception desk, and a staircase.

16. Krystal Urban Aeropuerto Cd de Mexico

Krystal Urban Aeropuerto Cd de Mexico
3.5 star property
11.2 km from Santo Domingo
9.0 out of 10, Wonderful, (1,284 reviews)
"Was very clean room ,breakfast exelent and big good drinks etc"
United States
esteban
The price is ฿2,373
฿2,836 total
includes taxes & fees
9 Nov - 10 Nov
Krystal Urban Aeropuerto Cd de Mexico
A modern hotel lobby with a circular reception desk, marble flooring, and a staircase leading to upper floors.

17. WeEnjoy Hotels Aeropuerto CDMX

WeEnjoy Hotels Aeropuerto CDMX
3.5 star property
10.8 km from Santo Domingo
9.2 out of 10, Wonderful, (5,429 reviews)
"Great place to stay"
United States
Erick
The price is ฿2,776
฿3,317 total
includes taxes & fees
9 Nov - 10 Nov
WeEnjoy Hotels Aeropuerto CDMX
An outdoor dining area with a table and chairs, surrounded by greenery and a modern building in the background.

18. Fiesta Americana Viaducto Aeropuerto

Fiesta Americana Viaducto Aeropuerto
4.0 star property
10.3 km from Santo Domingo
9.6 out of 10, Exceptional, (2,893 reviews)
"Very helpful staff, clean room and very comfortable bed."
United States
Delaney
The price is ฿5,060
฿6,046 total
includes taxes & fees
17 Nov - 18 Nov
Fiesta Americana Viaducto Aeropuerto
An indoor swimming pool with a red wall, steps leading into the pool, and lounge chairs with umbrellas.

19. Hotel Riazor Aeropuerto

Hotel Riazor Aeropuerto
3.5 star property
9.8 km from Santo Domingo
9.6 out of 10, Exceptional, (2,266 reviews)
"Great rooms, clean excellent restaurant friendly and helpful staff"
United States
Marianne
The price is ฿3,982
฿4,759 total
includes taxes & fees
1 Dec - 2 Dec
Hotel Riazor Aeropuerto
Front of property

20. Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico
4.0 star property
Venustiano Carranza, 14.5 km from Santo Domingo
8.8 out of 10, Excellent, (14,364 reviews)
"Very pleasant stay."
United States
Paula C
The price is ฿4,594
฿5,490 total
includes taxes & fees
1 Dec - 2 Dec
Camino Real Aeropuerto Mexico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santo Domingo

Find the best Santo Domingo areas for the activities you enjoy most.
An aerial view of a city with a central circular plaza, surrounded by buildings and trees.

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

A stone monument with inscriptions, surrounded by lush greenery and a clear sky.

Polanco

Visit the most diverse section of Mexico City for sophisticated shopping, dining, accommodations and sightseeing.

A row of colorful buildings with balconies and ornate doors.

La Condesa

Enjoy 20th-century history in these two sections of Mexico City, with interesting art and architecture reflecting European influences.

A grand building with a large golden dome and classical architecture.

Historic Center

Consider a visit to Zócalo and take some time to enjoy the interesting museums during your time in Historic Center. If you want to see more of the city, jump on the metro at Allende Station or Bellas Artes Station.

A brightly lit monument with a statue on top, surrounded by modern buildings.

Reforma

Consider a visit to Angel of Independence Monument and take some time to enjoy the important monuments during your time in Reforma. If you want to see more of the city, jump on the metro at Insurgentes Station or Cuauhtemoc Station.

Top Santo Domingo Hotel Reviews

Histórico Central Hotel

Histórico Central Hotel

10/10 Excellent
"Outstanding location to see the historic center , nice breakfast and snacks during the whole day, very helpful staff."
Mikayel 1-night trip
Posted less than an hour ago
Histórico Central Hotel

Frequently asked questions

What is Santo Domingo like?
Travellers to Mexico City's Santo Domingo neighbourhood will be sure to enjoy a stay here.
How many hotels will I find in the Santo Domingo area?
Book one of Expedia's 6 hotels and other accommodation options in Santo Domingo and start exploring everything Mexico City has to offer.
If I need to cancel my hotel reservation in Santo Domingo, will I receive a refund?
Yes, most room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to review the best deals available in Santo Domingo.
What are the top things to see and do in Santo Domingo?
Estadio Azteca, Centro Cultural y Social Veracruzano and Teatro Rafael Solana are just a few of the places to visit in and around Santo Domingo. While you're out sightseeing, Parroquia de San Juan Bautista and Casa del Teatro are a couple of additional sights to visit in Mexico City.