Santo Domingo Packages (Flight + Hotel)
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ฿27,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Where to stay in Santo Domingo
Find the best Santo Domingo areas and neighborhoods for the activities you enjoy most. Learn more about Santo Domingo
Roma Norte
Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.
Polanco
Visit the most diverse section of Mexico City for sophisticated shopping, dining, accommodations and sightseeing.
La Condesa
Enjoy 20th-century history in these two sections of Mexico City, with interesting art and architecture reflecting European influences.
Historic Center
2 out of top 10 points of interest in this area
Consider a visit to Zócalo and take some time to enjoy the interesting museums during your time in Historic Center. If you want to see more of the city, jump on the metro at Allende Station or Bellas Artes Station.
Reforma
1 out of top 10 points of interest in this area
Consider a visit to Angel of Independence Monument and take some time to enjoy the important monuments during your time in Reforma. If you want to see more of the city, jump on the metro at Insurgentes Station or Cuauhtemoc Station.
Top hotels in Santo Domingo
Camino Real Aeropuerto Mexico
Mexico City
Fully refundable
฿4,047
฿4,836 total
30 Aug - 31 Aug
includes taxes & fees
Hotel Zócalo Central
Cinco de Mayo 61 Mexico City
Fully refundableReserve now, pay when you stay
฿5,398
฿6,451 total
12 Aug - 13 Aug
includes taxes & fees
9.8/10 Exceptional! (2,830 reviews)
"The service was great. The room was clean and comfortable, and the building is beautiful. Food was excellent."
Reviewed on 11 Aug 2026
Fiesta Americana Reforma
Paseo De La Reforma 80 Mexico City CDMX
Fully refundableReserve now, pay when you stay
฿3,939
฿4,707 total
23 Aug - 24 Aug
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Santo Domingo holiday package cost?
We make it simple to see the world, with Santo Domingo packages starting from as low as . You'll have the flexibility to bundle your preferred airlines, hotels and car rental. For the ultimate getaway, why not add some activities and tours to your travel itinerary?
How do I get a cheap travel package to Santo Domingo?
Book everything all in one place with our Santo Domingo holiday packages. You'll discover deals on hotels, flights and more that'll keep your wallet happy and your spirit of adventure alive. And, with more than 550 partner airlines and 1,000,000 properties globally to choose from, there are endless opportunities to mix and match as you want.
Where should I stay in Santo Domingo?
Urban explorers come from every corner of the globe to see Basilica of Our Lady of Guadalupe and Zócalo in Santo Domingo. Book a hotel close to these top attractions and visit them at your leisure.
How far in advance should I book my Santo Domingo holiday?
It depends on the airline, but you can generally browse through international flights on Expedia nearly a year in advance. While it's generally recommended to book ahead of time, lucky travellers will sometimes find a cheaper ticket only weeks before the date of departure.
What does an Expedia Santo Domingo travel package include?
With Expedia, you can select a combination of hotels, car rentals and flights to build your ideal Santo Domingo package. Once you've made your booking, you can add on all the fun stuff like sightseeing tours and activities. Don't forget — the more you bundle, the more discounts you'll get!
What should I know before booking a Santo Domingo travel package?
When you book your hotels, flights and car rentals together, you'll enjoy amazing discounts. Whether you're planning a beach escape in a villa or want to stay in a comfortable hotel in the city, Expedia will help make it happen.
Can I choose my airline with a Santo Domingo Expedia holiday package?
Expedia has access to more than 550 airline partners globally, so you sure can! Just choose the carrier you want and craft your ideal Santo Domingo getaway.
If I'm not able to travel, can I cancel my Santo Domingo holiday package?
Don't stress if you're rethinking your Santo Domingo holiday package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur charges from your hotel, airline or car rental company. We totally understand your circumstances can suddenly change, so make your way to our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.
Things to do
Admission to Six Flags Mexico with roundtrip transportation
฿3,247
per adult
100% of travellers recommend
Mexico City Tourist Bus: Hop-On Hop-Off Service or Night Tour
฿430
per adult
84% of travellers recommend
Lucha Libre Mexican Wrestling Tour in Mexico City
฿2,052
per traveller
100% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.