Santo Domingo Packages (Flight + Hotel)

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    Save up to ฿4,531 when you book a flight and hotel together*

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Where to stay in Santo Domingo

Find the best Santo Domingo areas and neighborhoods for the activities you enjoy most. Learn more about Santo Domingo
Polanco which includes heritage architecture, a church or cathedral and a park

Polanco

5/5(6 area reviews)

Visit the most diverse section of Mexico City for sophisticated shopping, dining, accommodations and sightseeing.

Find hotels in Polanco

Top hotels in Santo Domingo

Fiesta Americana Reforma

Fiesta Americana Reforma

4 out of 5
Paseo De La Reforma 80, Col. Juarez, Mexico City, CDMX
Fully refundableReserve now, pay when you stay
The price is ฿4,396 per night from 16 Nov to 17 Nov
฿4,396
฿5,253 total
16 Nov - 17 Nov
includes taxes & fees
9.2/10 Wonderful! (3,842 reviews)
Excellent service, friendly staff and easy access!

Reviewed on 24 Oct 2025

Fiesta Americana Reforma
Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

4 out of 5
Mexico City
Fully refundable
The price is ฿3,602 per night from 22 Nov to 23 Nov
฿3,602
฿4,304 total
22 Nov - 23 Nov
includes taxes & fees
8.6/10 Excellent! (11,473 reviews)
.

Reviewed on 25 Oct 2025

Camino Real Aeropuerto Mexico
Galeria Plaza Reforma

Galeria Plaza Reforma

4 out of 5
Mexico City, CDMX
Fully refundableReserve now, pay when you stay
The price is ฿4,266 per night from 28 Oct to 29 Oct
฿4,266
฿5,097 total
28 Oct - 29 Oct
includes taxes & fees
9.2/10 Wonderful! (3,106 reviews)
Great location and clean room. Happy hour 7pm-9pm was amazing and had lot of great free options. Would definitely recommend this place for a visit to Mexico City.

Reviewed on 25 Oct 2025

Galeria Plaza Reforma
See all 6,044 properties in Santo Domingo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santo Domingo holiday package cost?
We make it simple to see the world, with Santo Domingo packages starting from as low as . You'll have the flexibility to bundle your preferred airlines, hotels and car rental. For the ultimate getaway, why not add some activities and tours to your travel itinerary?
How do I get a cheap travel package to Santo Domingo?
Book everything all in one place with our Santo Domingo holiday packages. You'll discover deals on hotels, flights and more that'll keep your wallet happy and your spirit of adventure alive. And, with more than 550 partner airlines and 1,000,000 properties globally to choose from, there are endless opportunities to mix and match as you want.
Where should I stay in Santo Domingo?
Urban explorers come from every corner of the globe to see Basilica of Our Lady of Guadalupe and Zócalo in Santo Domingo. Book a hotel close to these top attractions and visit them at your leisure.
How far in advance should I book my Santo Domingo holiday?
It depends on the airline, but you can generally browse through international flights on Expedia nearly a year in advance. While it's generally recommended to book ahead of time, lucky travellers will sometimes find a cheaper ticket only weeks before the date of departure.
What does an Expedia Santo Domingo travel package include?
With Expedia, you can select a combination of hotels, car rentals and flights to build your ideal Santo Domingo package. Once you've made your booking, you can add on all the fun stuff like sightseeing tours and activities. Don't forget — the more you bundle, the more discounts you'll get!
What should I know before booking a Santo Domingo travel package?
When you book your hotels, flights and car rentals together, you'll enjoy amazing discounts. Whether you're planning a beach escape in a villa or want to stay in a comfortable hotel in the city, Expedia will help make it happen.
Can I choose my airline with a Santo Domingo Expedia holiday package?
Expedia has access to more than 550 airline partners globally, so you sure can! Just choose the carrier you want and craft your ideal Santo Domingo getaway.
If I'm not able to travel, can I cancel my Santo Domingo holiday package?
Don't stress if you're rethinking your Santo Domingo holiday package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur charges from your hotel, airline or car rental company. We totally understand your circumstances can suddenly change, so make your way to our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.

Popular places to visit

Reforma which includes a monument, a garden and a city

Paseo de la Reforma

Like the Champs Elysées in Paris, this famous wide avenue provides a distinctive elegance to the historic plan of this huge global city.

Paseo de la Reforma
Zócalo

Zócalo

This is the heart of Mexico City with wide-ranging architecture, cultural events and a lively arts scene.

Zócalo
Basilica of Our Lady of Guadalupe showing a church or cathedral, religious elements and a square or plaza

Basilica of Our Lady of Guadalupe

Mexico’s patron saint, the Virgin of Guadalupe, is believed to have appeared on the site of this church, making it an important pilgrimage site for many Catholics.

Basilica of Our Lady of Guadalupe

Things to do

Red Turibus in Mexico City

Turibus Hop On - Hop Off Mexico City Tour

฿687
per adult
Turibus Hop On - Hop Off Mexico City Tour
Teotihuacan, Guadalupe Shrine, Tlatelolco & Tequila tasting

Teotihuacan, Guadalupe Shrine, Tlatelolco Full Day Tour

฿1,144
per adult
88% of travellers recommend
Teotihuacan, Guadalupe Shrine, Tlatelolco Full Day Tour
Skip-the-line Ticket to Templo Mayor

Templo Mayor Ticket

฿458
per adult
100% of travellers recommend
Templo Mayor Ticket
See all activities in Mexico City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.