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Our top choices for Santiago hotels

Hotel Gran David

Hotel Gran David
3.5 star property
Santiago
8.6 out of 10, Excellent, (387 reviews)
"Good hotel, good service and good breakfast"
Mexico
Kayser
The price is ฿2,453
฿2,699 total
includes taxes & fees
10 Apr - 11 Apr
Hotel Gran David

Hotel Mykonos Panama

Hotel Mykonos Panama
3.5 star property
Nuevo Santiago
8.8 out of 10, Excellent, (568 reviews)
"Very nice property and an excellent room "
United States
Larry
The price is ฿2,566
฿2,822 total
includes taxes & fees
11 Apr - 12 Apr
Hotel Mykonos Panama

Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes
3.0 star property
Nuevo Santiago
The price is ฿1,663
฿1,829 total
includes taxes & fees
13 Apr - 14 Apr
Hotel Plaza Los Tucanes

HOTEL VISTA LAGO

HOTEL VISTA LAGO
3.0 star property
La Pena
9.4 out of 10, Exceptional, (104 reviews)
"Great place to stay, quiet…"
United States
Eduardo
The price is ฿2,453
฿2,699 total
includes taxes & fees
17 Apr - 18 Apr
HOTEL VISTA LAGO

Cabañas Palma Real

Cabañas Palma Real
3.0 star property
Santiago Sur
The price is ฿1,905
฿2,416 total
includes taxes & fees
10 Apr - 11 Apr
Cabañas Palma Real
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Explore relaxing Santiago: its theme park, university life, cathedral and more!

UNESCO World Heritage Site Fort San Jeronimo located in Portobelo, Panama.

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Frequently asked questions

Where is the best place to stay in Santiago?
Hotel Gran David is one of the top choices for your stay based on our traveller data. This hotel offers free breakfast and a restaurant. Other good choices for your stay include HOTEL PLAZA COROTÚ and Hostal Travelers. See all available top hotels, or vacation rentals in Santiago.
If I need to cancel my hotel reservation in Santiago, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santiago.
What's the best budget-friendly hotel in Santiago?
Based on our traveller reviews, Hostal Travelers is a top choice for a less expensive stay. View all budget hotels in Santiago.
What's the best dog-friendly accommodation option in Santiago?
HOTEL CORPORATIVO PLAZA COROTÚ is a top hotel for people travelling with their pets, and offers a restaurant and free WiFi for its human guests. Hostal Travelers is another option if you're bringing your pet along. See more pet-friendly hotel accommodations in Santiago.
What are some accommodation options with pools in Santiago?
Hotel Gran David: Features a children's pool, an outdoor pool and a snack bar/deli. Hotel Mykonos Panama and HOTEL VISTA LAGO are a couple of other choices that offer an on-site pool. View all hotels with pools in Santiago.
What is staying in Santiago like?
Visitors to Santiago will definitely enjoy the restaurants. Tourists can also enjoy the city's theme park, university setting and bars. In Santiago, there are 6 hotels and other accommodation options to choose from. Find out more about Santiago.
What should I see while I'm in Santiago?
Landmarks like Escuela Normal Juan Demostenes Arosemena and Catedral of Santiago Apostol might be worth a visit. A couple of additional sights to add to your itinerary are Omar Torrijos Herrera Stadium and Plaza Banconal. Take a look at what more there is to see and do in Expedia's Santiago guide.
What's the seasonal weather like in Santiago?
The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and December, with an average of 25°C. The rainiest months in Santiago are October, August, June and November, with each month seeing an average of 447 mm of rainfall.