Find hotels in Santee, SC from ฿1,924
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Santee
Pet friendly
Family friendly
Check prices for these dates
Our top choices for Santee hotels

Tru By Hilton Santee
Tru By Hilton SanteeSantee
9.2 out of 10, Wonderful, (674 reviews)
The price is ฿3,357
฿3,726 total
includes taxes & fees
20 Jan - 21 Jan

Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott SanteeSantee
9.8 out of 10, Exceptional, (1,002 reviews)
The price is ฿3,796
฿4,214 total
includes taxes & fees
18 Jan - 19 Jan

Baymont by Wyndham Santee
Baymont by Wyndham SanteeSantee
8.0 out of 10, Very good, (1,430 reviews)
The price is ฿2,353
฿2,611 total
includes taxes & fees
12 Jan - 13 Jan

Hampton Inn Santee-I-95
Hampton Inn Santee-I-95Santee
9.6 out of 10, Exceptional, (1,001 reviews)
The price is ฿4,041
฿4,485 total
includes taxes & fees
22 Jan - 23 Jan

Best Western Plus Santee Inn
Best Western Plus Santee InnSantee
8.8 out of 10, Excellent, (1,002 reviews)
The price is ฿3,707
฿4,114 total
includes taxes & fees
18 Jan - 19 Jan

Holiday Inn Santee by IHG
Holiday Inn Santee by IHGSantee
8.2 out of 10, Very good, (986 reviews)
The price is ฿3,514
฿3,900 total
includes taxes & fees
8 Feb - 9 Feb

Comfort Inn & Suites Santee
Comfort Inn & Suites SanteeSantee
8.0 out of 10, Very good, (1,001 reviews)
The price is ฿3,227
฿3,582 total
includes taxes & fees
18 Jan - 19 Jan

Travelodge by Wyndham Santee
Travelodge by Wyndham SanteeSantee
7.0 out of 10, Good, (686 reviews)
The price is ฿1,945
฿2,159 total
includes taxes & fees
12 Jan - 13 Jan

Red Roof Inn Santee
Red Roof Inn SanteeSantee
6.6 out of 10, (642 reviews)
The price is ฿2,196
฿2,437 total
includes taxes & fees
12 Jan - 13 Jan

Super 8 by Wyndham Santee
Super 8 by Wyndham SanteeSantee
6.8 out of 10, (441 reviews)
The price is ฿2,353
฿2,612 total
includes taxes & fees
12 Jan - 13 Jan

Quality Inn & Suites Santee I-95
Quality Inn & Suites Santee I-95Santee
6.0 out of 10, (463 reviews)
The price is ฿1,707
฿2,068 total
includes taxes & fees
18 Jan - 19 Jan

Ramada by Wyndham Santee I-95
Ramada by Wyndham Santee I-95Santee
6.4 out of 10, (548 reviews)
The price is ฿2,089
฿2,319 total
includes taxes & fees
25 Jan - 26 Jan

Econo Lodge Santee
Econo Lodge SanteeSantee
6.4 out of 10, (310 reviews)
The price is ฿1,985
฿2,204 total
includes taxes & fees
25 Jan - 26 Jan

Tru by Hilton Orangeburg
Tru by Hilton OrangeburgOrangeburg
9.2 out of 10, Wonderful, (1,003 reviews)
The price is ฿3,319
฿3,684 total
includes taxes & fees
25 Jan - 26 Jan

Fairfield Inn by Marriott Orangeburg
Fairfield Inn by Marriott OrangeburgOrangeburg
8.4 out of 10, Very good, (709 reviews)
The price is ฿2,635
฿2,925 total
includes taxes & fees
18 Jan - 19 Jan

Hampton Inn & Suites Orangeburg
Hampton Inn & Suites OrangeburgOrangeburg
9.4 out of 10, Exceptional, (767 reviews)
The price is ฿3,576
฿3,969 total
includes taxes & fees
25 Jan - 26 Jan

SureStay Hotel by Best Western Manning
SureStay Hotel by Best Western ManningManning
8.6 out of 10, Excellent, (1,002 reviews)
The price is ฿2,792
฿3,099 total
includes taxes & fees
1 Feb - 2 Feb

Spark by Hilton Orangeburg
Spark by Hilton OrangeburgOrangeburg
7.8 out of 10, Good, (1,003 reviews)
The price is ฿2,736
฿3,037 total
includes taxes & fees
1 Feb - 2 Feb

SpringHill Suites by Marriott Orangeburg
SpringHill Suites by Marriott OrangeburgOrangeburg
8.8 out of 10, Excellent, (683 reviews)
The price is ฿3,561
฿3,953 total
includes taxes & fees
17 Jan - 18 Jan

Holiday Inn Express & Suites Orangeburg by IHG
Holiday Inn Express & Suites Orangeburg by IHGOrangeburg
8.6 out of 10, Excellent, (797 reviews)
The price is ฿3,827
฿4,248 total
includes taxes & fees
25 Jan - 26 Jan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Santee attractions
Learn more about Santee
Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campsites.

More cheap stays in Santee

Baymont by Wyndham Orangeburg North
3583 Saint Matthews Rd Orangeburg SC
The price is ฿1,733 per night from 18 Jan to 19 Jan
฿1,733
฿1,924 total
18 Jan - 19 Jan
includes taxes & fees
5.8/10 (1,002 reviews)



































































