Find hotels in Santee, SC from ฿1,928
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Santee
Pet friendly
Family friendly
Check prices for these dates
Our top choices for Santee hotels

Tru By Hilton Santee
Tru By Hilton SanteeSantee
9.2 out of 10, Wonderful, (674 reviews)
The price is ฿3,333
฿3,699 total
includes taxes & fees
2 Feb - 3 Feb

Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott SanteeSantee
9.8 out of 10, Exceptional, (1,002 reviews)
The price is ฿3,796
฿4,214 total
includes taxes & fees
9 Feb - 10 Feb

Baymont by Wyndham Santee
Baymont by Wyndham SanteeSantee
8.0 out of 10, Very good, (1,428 reviews)
The price is ฿2,353
฿2,611 total
includes taxes & fees
9 Feb - 10 Feb

Best Western Plus Santee Inn
Best Western Plus Santee InnSantee
8.8 out of 10, Excellent, (1,002 reviews)
The price is ฿3,715
฿4,123 total
includes taxes & fees
18 Jan - 19 Jan

Holiday Inn Santee by IHG
Holiday Inn Santee by IHGSantee
8.2 out of 10, Very good, (984 reviews)
The price is ฿3,702
฿4,109 total
includes taxes & fees
9 Feb - 10 Feb

Hampton Inn Santee-I-95
Hampton Inn Santee-I-95Santee
9.6 out of 10, Exceptional, (1,001 reviews)
The price is ฿4,049
฿4,495 total
includes taxes & fees
22 Jan - 23 Jan

Comfort Inn & Suites Santee
Comfort Inn & Suites SanteeSantee
8.0 out of 10, Very good, (1,001 reviews)
The price is ฿3,234
฿3,589 total
includes taxes & fees
18 Jan - 19 Jan

Travelodge by Wyndham Santee
Travelodge by Wyndham SanteeSantee
7.0 out of 10, Good, (686 reviews)
The price is ฿1,945
฿2,159 total
includes taxes & fees
9 Feb - 10 Feb

Quality Inn & Suites Santee I-95
Quality Inn & Suites Santee I-95Santee
6.0 out of 10, (462 reviews)
The price is ฿1,707
฿2,068 total
includes taxes & fees
9 Feb - 10 Feb

Red Roof Inn Santee
Red Roof Inn SanteeSantee
6.6 out of 10, (642 reviews)
The price is ฿2,200
฿2,443 total
includes taxes & fees
11 Jan - 12 Jan

Super 8 by Wyndham Santee
Super 8 by Wyndham SanteeSantee
6.8 out of 10, (441 reviews)
The price is ฿2,353
฿2,612 total
includes taxes & fees
9 Feb - 10 Feb

Ramada by Wyndham Santee I-95
Ramada by Wyndham Santee I-95Santee
6.4 out of 10, (548 reviews)
The price is ฿2,527
฿2,804 total
includes taxes & fees
19 Jan - 20 Jan

Econo Lodge Santee
Econo Lodge SanteeSantee
6.4 out of 10, (310 reviews)
The price is ฿1,990
฿2,208 total
includes taxes & fees
25 Jan - 26 Jan

Fairfield Inn by Marriott Orangeburg
Fairfield Inn by Marriott OrangeburgOrangeburg
8.4 out of 10, Very good, (708 reviews)
The price is ฿2,641
฿2,931 total
includes taxes & fees
18 Jan - 19 Jan

Tru by Hilton Orangeburg
Tru by Hilton OrangeburgOrangeburg
9.2 out of 10, Wonderful, (1,003 reviews)
The price is ฿3,326
฿3,692 total
includes taxes & fees
25 Jan - 26 Jan

Spark by Hilton Orangeburg
Spark by Hilton OrangeburgOrangeburg
7.8 out of 10, Good, (1,003 reviews)
The price is ฿2,736
฿3,037 total
includes taxes & fees
8 Feb - 9 Feb

Best Inn of Manning
Best Inn of ManningManning
7.8 out of 10, Good, (12 reviews)
The price is ฿2,303
฿2,557 total
includes taxes & fees
19 Jan - 20 Jan

Hampton Inn & Suites Orangeburg
Hampton Inn & Suites OrangeburgOrangeburg
9.4 out of 10, Exceptional, (767 reviews)
The price is ฿3,578
฿3,971 total
includes taxes & fees
8 Feb - 9 Feb

SureStay Hotel by Best Western Manning
SureStay Hotel by Best Western ManningManning
8.6 out of 10, Excellent, (1,001 reviews)
The price is ฿2,792
฿3,099 total
includes taxes & fees
5 Feb - 6 Feb

Comfort Inn & Suites Orangeburg
Comfort Inn & Suites OrangeburgOrangeburg
8.0 out of 10, Very good, (562 reviews)
The price is ฿2,993
฿3,322 total
includes taxes & fees
18 Jan - 19 Jan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Santee attractions
Learn more about Santee
Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campsites.

More cheap stays in Santee

Baymont by Wyndham Orangeburg North
3583 Saint Matthews Rd Orangeburg SC
The price is ฿1,737 per night from 19 Jan to 20 Jan
฿1,737
฿1,928 total
19 Jan - 20 Jan
includes taxes & fees
5.8/10 (1,002 reviews)



































































