An aerial view of a coastal landscape with a dam, farmland, and dense forests.

Search Family-Friendly Hotels in Santee

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Santee Family-Friendly Hotels

Tonight
13 Oct - 14 Oct
Tomorrow
14 Oct - 15 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Santee family-friendly hotels

1. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
Santee
  • A family escape that offers vibrant pool days, premium entertainment, and free breakfast just minutes from Santee State Park.
฿4,647
฿5,158 total
includes taxes & fees
22 Oct - 23 Oct
Fairfield Inn & Suites by Marriott Santee

2. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
Santee
  • Family fun for everyone at this Santee hotel with a seasonal pool, free breakfast, and kid-friendly extras.
฿3,963
฿4,399 total
includes taxes & fees
2 Nov - 3 Nov
Hampton Inn Santee-I-95

3. Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
  • Family holiday paradise with an outdoor pool, fitness centre, and quiet, pet-friendly atmosphere for your whole family.
฿4,675
฿5,189 total
includes taxes & fees
14 Oct - 15 Oct
Best Western Plus Santee Inn

4. Tru By Hilton Santee

Tru By Hilton Santee
Santee
฿3,402
฿3,776 total
includes taxes & fees
1 Nov - 2 Nov
Tru By Hilton Santee

5. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
  • Family-friendly escape at Santee with seasonal outdoor pool, free breakfast, and steps from the state park.
฿3,478
฿3,860 total
includes taxes & fees
8 Nov - 9 Nov
Comfort Inn & Suites Santee

6. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
Santee
  • Family adventure awaits at this Holiday Inn with an indoor pool, premium TV channels, and water sports equipment nearby.
฿3,195
฿3,546 total
includes taxes & fees
18 Oct - 19 Oct
Holiday Inn Santee by IHG

7. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
Santee
฿2,146
฿2,382 total
includes taxes & fees
22 Oct - 23 Oct
Travelodge by Wyndham Santee

8. Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
Santee
฿2,138
฿2,373 total
includes taxes & fees
26 Oct - 27 Oct
Super 8 by Wyndham Santee/I-95

9. Red Roof Inn Santee

Red Roof Inn Santee
Santee
฿2,112
฿2,344 total
includes taxes & fees
26 Oct - 27 Oct
Red Roof Inn Santee

10. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
Santee
฿1,830
฿2,199 total
includes taxes & fees
3 Nov - 4 Nov
Quality Inn & Suites Santee I-95
View all properties

Choose what matters most at family-friendly hotels in Santee

Breakfast included
Pool
All-inclusive
4 stars
5 stars

Family-friendly hotels with free breakfast in Santee

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
Santee
฿4,647
฿5,158 total
includes taxes & fees
22 Oct - 23 Oct
Fairfield Inn & Suites by Marriott Santee

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
Santee
฿3,963
฿4,399 total
includes taxes & fees
2 Nov - 3 Nov
Hampton Inn Santee-I-95

Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
฿4,675
฿5,189 total
includes taxes & fees
14 Oct - 15 Oct
Best Western Plus Santee Inn

Tru By Hilton Santee

Tru By Hilton Santee
Santee
฿3,402
฿3,776 total
includes taxes & fees
1 Nov - 2 Nov
Tru By Hilton Santee

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
฿3,478
฿3,860 total
includes taxes & fees
8 Nov - 9 Nov
Comfort Inn & Suites Santee

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
Santee
฿3,195
฿3,546 total
includes taxes & fees
18 Oct - 19 Oct
Holiday Inn Santee by IHG

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
Santee
฿2,146
฿2,382 total
includes taxes & fees
22 Oct - 23 Oct
Travelodge by Wyndham Santee

Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
Santee
฿2,138
฿2,373 total
includes taxes & fees
26 Oct - 27 Oct
Super 8 by Wyndham Santee/I-95

Red Roof Inn Santee

Red Roof Inn Santee
Santee
฿2,112
฿2,344 total
includes taxes & fees
26 Oct - 27 Oct
Red Roof Inn Santee

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
Santee
฿1,830
฿2,199 total
includes taxes & fees
3 Nov - 4 Nov
Quality Inn & Suites Santee I-95
View all properties

Family-friendly hotels with pools in Santee

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
Santee
฿4,647
฿5,158 total
includes taxes & fees
22 Oct - 23 Oct
Fairfield Inn & Suites by Marriott Santee

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
Santee
฿3,963
฿4,399 total
includes taxes & fees
2 Nov - 3 Nov
Hampton Inn Santee-I-95

Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
฿4,675
฿5,189 total
includes taxes & fees
14 Oct - 15 Oct
Best Western Plus Santee Inn

Tru By Hilton Santee

Tru By Hilton Santee
Santee
฿3,402
฿3,776 total
includes taxes & fees
1 Nov - 2 Nov
Tru By Hilton Santee

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
฿3,478
฿3,860 total
includes taxes & fees
8 Nov - 9 Nov
Comfort Inn & Suites Santee

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
Santee
฿3,195
฿3,546 total
includes taxes & fees
18 Oct - 19 Oct
Holiday Inn Santee by IHG

Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
Santee
฿2,138
฿2,373 total
includes taxes & fees
26 Oct - 27 Oct
Super 8 by Wyndham Santee/I-95

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
Santee
฿1,830
฿2,199 total
includes taxes & fees
3 Nov - 4 Nov
Quality Inn & Suites Santee I-95

Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
Santee
฿2,603
฿2,889 total
includes taxes & fees
14 Oct - 15 Oct
Ramada by Wyndham Santee I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santee Hotel Reviews

Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg

8/10 Good
"Hotel is dated however it is perfect for an overnight traveler. Internet was intermittent at best."
Chris 1-night trip
Posted 1 hour ago
Travelodge by Wyndham Orangeburg
SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning

10/10 Excellent
"I like everything. And when I went to get coffee the lady cleaning in there was so nice."
Latonya 1-night trip
Posted 21 hours ago
SureStay Hotel by Best Western Manning
Baymont by Wyndham Santee

Baymont by Wyndham Santee

10/10 Excellent
":)"
Robert 1-night trip
Posted 2 days ago
Baymont by Wyndham Santee
Spark by Hilton Orangeburg

Spark by Hilton Orangeburg

8/10 Good
"No hot breakfast"
Randolph 1-night trip
Posted 2 days ago
Spark by Hilton Orangeburg
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

10/10 Excellent
"Nice bed, water was very hot which is nice, and satellite TV with tons of channels."
Robert 1-night trip
Posted 3 days ago
Travelodge by Wyndham Santee
Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg

10/10 Excellent
"We stayed one night but it was clean, the bed was comfortable, and the breakfast provided was very good."
Melissa 1-night trip
Posted 5 days ago
Super 8 by Wyndham, Orangeburg

Frequently asked questions

What's Santee like for family-friendly holidays?
The welcoming destination of Santee is a great choice if you've been thinking about a holiday with the children. The excursions, lake views and golf are just a few things that make this an attractive holiday destination for families. Arrange a flight into Columbia, SC (CAE-Columbia Metropolitan), which is located 49 mi (78.8 km) from the city centre.
What's the best family accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another good option for your family trip.
When's the best time to book a family-friendly holiday in Santee?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Santee is 1397 mm.
What's there to see and do with your family in Santee?
While you and the family are holidaying in Santee, you may want to explore some of the attractions here such as Orangeburg County Library Mentor Branch, Lake Marion and Taw Caw Creek Park. Make sure that you have lots of time for activities such as Congaree National Park and Santee National Wildlife Refuge.

Explore a world of travel with Expedia