Santa Fe Packages (Flight + Hotel)

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ฿4,531 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Santa Fe

Find the best Santa Fe areas and neighborhoods for the activities you enjoy most. Learn more about Santa Fe
El Castillo Museum showing heritage architecture and château or palace

El Poblado

6 out of top 10 points of interest in this area
4/5(28 area reviews)

El Poblado is highly notable for its popular shops, and you might want to visit top sights like Golden Mile and Oviedo Shopping Center. See more of Medellín by jumping on the metro at Poblado Station or Aguacatala Station.

Find hotels in El Poblado

Top hotels in Santa Fe

Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

3.5 out of 5
# 37-40 Calle 9A Medellín
Fully refundable
The price is ฿2,411 per night from 23 Feb to 24 Feb
฿2,411
฿2,411 total
23 Feb - 24 Feb
9/10 Wonderful! (395 reviews)
Beautiful place. Amazing service. Great location and food was delicious. Highly recommend this place. The manager Eduardo was so helpful and kind, even with a little hiccup he handled it very quickly and I was very satisfied. I will definitely come back and stay here.

Reviewed on 24 Jan 2026

Calle Flora Hotel by Jalo
Heiss Hotel By Jalo

Heiss Hotel By Jalo

4 out of 5
1460 Cra. 43F Medellín Antioquia
Fully refundableReserve now, pay when you stay
The price is ฿1,840 per night from 25 Feb to 26 Feb
฿1,840
฿1,840 total
25 Feb - 26 Feb
9/10 Wonderful! (1,150 reviews)
Everything very professional y handle.

Reviewed on 26 Jan 2026

Heiss Hotel By Jalo
Hotel Dorado La 70

Hotel Dorado La 70

4 out of 5
Carrera 70 No 44 B-66 Medellín
Fully refundableReserve now, pay when you stay
8.8/10 Excellent! (1,827 reviews)
Staff, clean room, safety with uber calls and 24/7 security

Reviewed on 25 Jan 2026

Get rates
Hotel Dorado La 70
See all 4,257 properties in Santa Fe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Fe holiday package cost?
Starting from as little as , you can tailor make your Santa Fe holiday package. Simply bundle flights, hotels and car rentals and we'll reward you with discounts.
How do I get a cheap travel package to Santa Fe?
Booking a flight and hotel together with Expedia won't just save precious time — it'll save you cash too. A Santa Fe holiday package makes it easy to put together the ideal trip. With more than 550 airlines across the world to pick from, finding flights that fit your schedule won't be a hassle. In addition to that, we've got over 1,000,000 properties globally to choose from. Now that's what we call choice. Whatever your budget, Expedia will help show you the world.
Where should I stay in Santa Fe?
Holiday Makers come from near and far to see Atanasio Giradot Stadium and Botero Plaza in Santa Fe. Stay within a stone's throw of these wonderful attractions and visit them whenever you please.
What are the top hotels in Santa Fe?
Hostel Ventura and La Palmera In Medellin are two of the most sought-after properties in Santa Fe. Why not check out the amenities and facilities at each and then decide?
How far in advance should I book my Santa Fe holiday?
It depends on the air carrier, but you can usually browse through international airfares on Expedia nearly a year in advance. While it's generally recommended to book ahead of time, lucky customers occasionally score a cheaper seat only weeks before departure dates.
What does an Expedia Santa Fe travel package include?
Car rentals, flights and hotels — we connect you to all the best deals. All you have to do is pick and choose your preferred combination. Once you've made your booking, you can add on the fun stuff like tours and experiences. Our travel packages make it easy to put together an unforgettable Santa Fe trip.
What should I know before booking a Santa Fe travel package?
Booking all the parts of your trip together is a simple way to save. Bundle your flights, car rentals and hotels into a neat little package. But you're not limited to hotels. Expedia offers all types of properties, including holiday rentals such as mountain cabins and short-term homes. Your choices are almost endless!
Can I choose my airline with a Santa Fe Expedia holiday package?
Yes, you're in control. We have access to over 550 airlines all over the world, so you can tailor your Santa Fe adventure according to your budget and style.
If I'm not able to travel, can I cancel my Santa Fe holiday package?
Because we know life can throw you a few curveballs, the answer is yes. For further details, visit our Customer Service Portal. But generally speaking, if you've booked your Santa Fe holiday package in the last 24 hours, you may be able to cancel or change it with no penalties. Your airline, hotel or car rental company may charge a fee if you made your booking a while ago.

Popular places to visit

Foto aérea del Parque de El Poblado, en la ciudad de Medellín, aparece la Iglesia de San José, Católica.

Poblado Park

After visiting Poblado Park, make a plan to see the other sights and activities in Medellín. Visit the shops and lively bars in this walkable area.

Poblado Park
Botero Square Sculpture Park featuring heritage architecture, a city and a square or plaza

Botero Plaza

Walk among comically obese statues made by the illustrious artist Fernando Botero in this spacious plaza full of artisans and restaurants.

Botero Plaza

Oviedo Shopping Center

During your visit to Medellín, you can do some window-shopping at Oviedo Shopping Center. Visit the lively bars or top-notch restaurants in this walkable area.

Oviedo Shopping Center

Things to do

Day Trip To Guatapé with ,Breakfast, Lunch and Boat Ride

Day Trip To Guatapé with ,Breakfast, Lunch and Boat Ride

฿1,147
per adult
98% of travellers recommend
Day Trip To Guatapé with ,Breakfast, Lunch and Boat Ride
Comuna 13 Graffiti Tour with Street Food

Comuna 13 Graffiti Tour with Street Food

฿526
per adult
98% of travellers recommend
Comuna 13 Graffiti Tour with Street Food
PREMIUM Guatapé Tour: Rock, Luxury boat ride, Meals & Llamas

PREMIUM Guatapé Tour: Rock, Luxury boat ride, Meals & Llamas

฿1,243
per adult
94% of travellers recommend
PREMIUM Guatapé Tour: Rock, Luxury boat ride, Meals & Llamas
See all activities in Medellin
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.