Santa Cruz Packages (Flight + Hotel)
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ฿4,531 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top hotels in Santa Cruz
Camino Real Hotel
Av. San Martín y 4to. Anillo Santa Cruz
The price is ฿4,228 per night from 1 Apr to 2 Apr
฿4,228
฿4,228 total
1 Apr - 2 Apr
9/10 Wonderful! (421 reviews)
Good property the great amenities and service
Reviewed on 24 Mar 2026
Ibis Santa Cruz DE LA Sierra
AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
The price is ฿1,786 per night from 28 Mar to 29 Mar
฿1,786
฿1,786 total
28 Mar - 29 Mar
9.6/10 Exceptional! (97 reviews)
Good
Reviewed on 8 Mar 2026
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Ave. San Martin, #455 Santa Cruz
The price is ฿4,837 per night from 19 Apr to 20 Apr
฿4,837
฿4,837 total
19 Apr - 20 Apr
9/10 Wonderful! (365 reviews)
Yes
Reviewed on 8 Mar 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
What to do in Santa Cruz
Santa Cruz: Wildlife Sanctuary and Preservation Park Tour
฿2,639
per adult
Samaipata Fort Tour: Ancient Ruins in 1 Full Day
฿9,779
per adult
3D/2N Getaway on the Che Guevara Route Live the Adventure!
฿21,700
per adult
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
