Search Holiday Rentals in Santa Cruz

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Our top choices for Santa Cruz holiday rentals

Apartment in Sabana Abajo

Segovia Studio Units
3.0 star property
8.6 out of 10, Excellent, (739)
"Very nice, clean and great wifi"
United States
Michael Brian
Segovia Studio Units

Villa in Pitahaya

SELVA by DW
4.0 star property
10.0 out of 10, Exceptional, (2)
"This was our 1st experience in PR. This house was AMAZINGLY beautiful and really show cased the outdoor space!! It was VERY clean, high quality linens. Had a nice cook space. The space it self was STUNNING!! The outdoor space was PERFECTION!!!! We actually booked for the lounge net area, and it did not disappoint!! **Downfalls [we understand that somethings are out of anyones control so more of a FYI] -There was nothing "comfy" about the house. It is all cement: bed frame, entire bathroom so...
United States
Jamie leigh
SELVA by DW

Holiday Home in Naguabo

Casa Parcha
3.5 star property
10.0 out of 10, Exceptional, (33)
"This retreat was exactly what I was looking for. It offered a quiet stay surrounded by nature. I gave me a chance to reconnect with myself and to enjoy the glorious sounds of the coqui. The communication was top notch. Everyone I encountered was extremely friendly and available to assists with all my needs. This is definitely a gem. "
United States
Ileana
The price is ฿5,283
฿6,119 total
includes taxes & fees
31 Dec - 1 Jan 2026
Casa Parcha

Villa in Zarzal

Picuas Village
3.0 star property
7.4 out of 10, Good, (59)
"Tranquil"
United States
Edia
The price is ฿6,755
฿9,558 total
includes taxes & fees
21 Jan - 22 Jan 2026
Picuas Village

Villa in Santurce

MANSION MIRAFLORES
3.0 star property
9.4 out of 10, Exceptional, (145)
"Clean room , amenities and great location"
United States
Elisabeth
The price is ฿4,699
฿6,307 total
includes taxes & fees
4 Jan - 5 Jan 2026
MANSION MIRAFLORES

Aparthotel in San Juan Antiguo

Romeo Gay Hotel
4.0 star property
9.0 out of 10, Wonderful, (145)
"Great place"
United States
pietro
Romeo Gay Hotel

Aparthotel in Isla Verde

ESJ by PMI Puerto Rico
3.5 star property
7.0 out of 10, Good, (38)
"Very comfortable, great view and clean "
United States
Daniela
The price is ฿3,543
฿6,503 total
includes taxes & fees
13 Jan - 14 Jan 2026
ESJ by PMI Puerto Rico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
  • Use the map to find apartments and other holiday homes in the Santa Cruz neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Cruz while they last

Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Can I find a holiday rental in Santa Cruz?

Yes, there are holiday rentals close to the most popular sights in Santa Cruz, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that Santa Cruz has to offer?

150 Sol by Stay with Bear: This holiday home rental outside of Santa Cruz is in the historical district, and equipped with air conditioning and Netflix to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a full-sized fridge, a stovetop and a microwave.

What can I see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Carabali Rainforest Park, or get outside and enjoy nature at El Yunque National Forest. Other popular places to visit in the area include Port of San Juan and Condado Beach.

What are holiday rentals like in Santa Cruz?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Santa Cruz. Holiday rentals offer extras such as kitchens and laundry facilities so you'll feel right at home. If you're concerned about cleanliness, a holiday rental can offer a sense of safety away from shared hotel lifts and busy lobbies while still allowing you the excitement and enjoyment of travel. You'll also find more space in a holiday rental than in a standard hotel, which makes a holiday rental a great choice for families.