Santa Clara Packages (Flight + Hotel)

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Where to stay in Santa Clara

Find the best Santa Clara areas and neighborhoods for the activities you enjoy most. Learn more about Santa Clara
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Casco Viejo

3.5/5(3 area reviews)

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Find hotels in Casco Viejo

Top hotels in Santa Clara

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is ฿3,716 per night from 25 Aug to 26 Aug
฿3,716
฿4,088 total
25 Aug - 26 Aug
includes taxes & fees
9/10 Wonderful! (4,153 reviews)
"No tenían abierta la alberca"

Reviewed on 14 Aug 2025

Hotel Riu Plaza Panama
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Fully refundableReserve now, pay when you stay
The price is ฿2,617 per night from 16 Aug to 17 Aug
฿2,617
฿2,879 total
16 Aug - 17 Aug
includes taxes & fees
9/10 Wonderful! (405 reviews)
"The check-in process was quick and easy although there was only one person working and there were several persons waiting to check-in. The room and lobby area were clean. The breakfast had several options which was great. I stayed there during the week previously abd the brekafast was the normal ..."

Reviewed on 11 Aug 2025

Waymore Hotel Spa & Casino
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is ฿2,478 per night from 18 Aug to 19 Aug
฿2,478
฿2,726 total
18 Aug - 19 Aug
includes taxes & fees
7.6/10 Good! (1,002 reviews)
"The hotel was very nice but we never did have hot water in the bathroom the whole time we were there."

Reviewed on 8 Aug 2025

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
See all 1,513 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Clara holiday package cost?
Custom make your Santa Clara holiday package from as little as . Pick from any combination of hotels, flights and rental cars to craft the escape of your dreams. Be sure to add on some tours and experiences!
How do I get a cheap travel package to Santa Clara?
One of the easiest ways to save cash (and time) is to bundle your bookings with Expedia. Hotels, rental cars, flights and activities — we've got them all. Select the combination that best fits you and watch your savings grow. Of course, a travel package is never a one-size-fits-all. That's why we offer more than 550 air carriers and 1,000,000 hotels throughout the world, which lets you customize your Santa Clara getaway.
Where should I stay in Santa Clara?
Most travellers who visit Santa Clara include Miraflores Locks and Metropolitan Cathedral of Panama on their must-see lists. Why not select a hotel close to one of these main attractions?
How far in advance should I book my Santa Clara holiday?
Savvy travellers always book early. Air carriers generally advertise flights up to a year prior to departure, and this is a fantastic opportunity to score some of the cheapest prices. Just been told you should take some holiday time next week? No need to worry. Expedia are never short on fantastic deals to whisk you away on the getaway of your dreams, at an affordable price.
What does an Expedia Santa Clara travel package include?
It comes down to what you're looking for. If you're travelling solo, you might decide to combine hotels and flights. Bringing the whole family to Santa Clara? A travel package including flights, hotels and rental cars might suit you better. Expedia gives you the flexibility and freedom to tailor-make your travel package.
What should I know before booking a Santa Clara travel package?
When you book your flights, hotels and car rentals together, you'll pick up awesome discounts. Whether you're organising a beach break in a villa or prefer to stay in an upscale city hotel, Expedia can make it happen for less.
Can I choose my airline with a Santa Clara Expedia holiday package?
Yes, you can. We offer more than 550 airline partners throughout the world, so opt for the carrier that fits your budget and travel needs.
If I'm not able to travel, can I cancel my Santa Clara holiday package?
Because we understand life is full of surprises, the answer is yes. For further details, check out our Customer Service Portal. But generally speaking, if you've made your booking in the last 24 hours, you may be able to change or cancel it for no charge. Your hotel, airline or car rental company may impose a fee if you made your booking a while ago.

Popular places to visit

Panama Canal Railway

Panama Canal Railway

Enjoy an outing to Panama Canal Railway during your stay in Ancon. Stroll along the seaside or visit the shops in this culturally rich area.

Panama Canal Railway

Things to do

Slingshot Tour Panama

Slingshot Tour Panama

฿3,778
per adult
76% of travellers recommend
Slingshot Tour Panama
Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

฿4,880
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
Panama City: Poin Glass Observation Deck Ticket with VR Tour

Panama City: Poin Glass Observation Deck Ticket with VR Tour

฿1,051
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
See all activities in Panama City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.