Mission Valley Travel Guide

San Diego

Mission Valley
Mission Valley
Photo by Robert Tickell
Photo by Deb Loom
Photo by Hilary Hancock

Popular places to visit

Things to do


Top hotels in Mission Valley

Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the pool and the bar in their ...
8/10 Very Good! (1,926 reviews)
"Loved how close it was to the zoo and the beach ."

Reviewed on 4 Aug 2025

Handlery Hotel
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 out of 5
2151 Hotel Circle South, San Diego, CA
The price is ฿4,239 per night from 17 Aug to 18 Aug
฿4,239
฿4,872 total
17 Aug - 18 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,162 reviews)
"It was hard to get good service! The front desk was not a happy place!"

Reviewed on 4 Aug 2025

Hampton Inn San Diego/Mission Valley
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S, San Diego, CA
The price is ฿3,171 per night from 2 Sept to 3 Sept
฿3,171
฿3,645 total
2 Sept - 3 Sept
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free Wi-Fi, a fitness centre and parking (surcharge). Our guests praise the helpful staff and ...
7.8/10 Good! (2,265 reviews)
"It was a decent room for the price"

Reviewed on 2 Aug 2025

Days Inn by Wyndham San Diego Hotel Circle
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is ฿3,815 per night from 14 Aug to 15 Aug
฿3,815
฿4,385 total
14 Aug - 15 Aug
includes taxes & fees
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free Wi-Fi, breakfast (surcharge) and 24-hour room service. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,469 reviews)
"Customer service, beds and sheets wonderful. Amazing view from room. Good location."

Reviewed on 2 Aug 2025

Sheraton Mission Valley San Diego Hotel
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S, San Diego, CA
The price is ฿4,044 per night from 12 Aug to 13 Aug
฿4,044
฿4,649 total
12 Aug - 13 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,855 reviews)
"Great stay"

Reviewed on 29 Jul 2025

Hilton San Diego Mission Valley
Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area

Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area

3 out of 5
2201 Hotel Circle S, San Diego, CA
The price is ฿4,946 per night from 17 Aug to 18 Aug
฿4,946
฿5,685 total
17 Aug - 18 Aug
includes taxes & fees
Stay at this family-friendly hotel in San Diego. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,048 reviews)
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Reviewed on 2 Aug 2025

Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Mission Valley

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Hillcrest

5/5(1 area review)

Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.

Hillcrest
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North Park

North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.

North Park
Old Town San Diego State Park featuring signage

Old Town San Diego

4/5(5 area reviews)

The abundant dining options and seaside views are top of the list for many visitors to Old Town San Diego. A stop by Old Town San Diego State Park or Whaley House Museum might round out your trip.

Old Town San Diego
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Little Italy

Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.

Little Italy
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Downtown San Diego

4.5/5(138 area reviews)

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Downtown San Diego
Gaslamp Quarter featuring a bar, night scenes and street scenes

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Gaslamp Quarter

Mission Valley Travel Guide