San Antonio Packages (Flight + Hotel)

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  • Better together

    Save up to ฿4,531 when you book a flight and hotel together*

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Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most. Learn more about San Antonio
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Amelia Denis de Icaza

While there might not be top attractions in Amelia Denis de Icaza, you can explore the larger area and discover places like El Dorado Mall and Panama Viejo.

Find hotels in Amelia Denis de Icaza

Top hotels in San Antonio

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4 out of 5
Avenida Domingo Diaz via Tocumen San Miguelito Panama
Fully refundableReserve now, pay when you stay
The price is ฿3,704 per night from 11 Apr to 12 Apr
฿3,704
฿4,075 total
11 Apr - 12 Apr
includes taxes & fees
Courtyard by Marriott Panama Metromall
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
The price is ฿5,366 per night from 5 Apr to 6 Apr
฿5,366
฿5,903 total
5 Apr - 6 Apr
includes taxes & fees
9/10 Wonderful! (5,154 reviews)
the 15th floor had a little bad scent including my room it was uncomfortable for the first couple hours.

Reviewed on 25 Mar 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
The price is ฿4,944 per night from 10 Apr to 11 Apr
฿4,944
฿5,438 total
10 Apr - 11 Apr
includes taxes & fees
8.6/10 Excellent! (2,494 reviews)
Clean room / staff / airport shuttle / outdoor pool

Reviewed on 24 Mar 2026

Crowne Plaza Panama Airport by IHG
See all 1,613 properties in San Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a San Antonio holiday package cost?
Choose from any combination of car rentals, flights and hotels, and you can be holidaying in San Antonio from just . And the more you bundle, the more cash you save. The holiday of your dreams has never been more affordable.
How do I get a cheap travel package to San Antonio?
Our San Antonio holiday packages promise plenty of savings for the savvy traveller. For the best deal, simply combine your flights, hotels and extras (including tours) into one neat package. But great bargains are only the start of your next unforgettable adventure. Book with Expedia and and you'll have over 550 airlines and 1,000,000 hotel options across the globe to pick from. Whatever your budget or style, there's a holiday package that's perfect for you.
Where should I stay in San Antonio?
If you're interested in visiting Metromall Panama, give commuting a miss and book a hotel nearby. It's one of the best attractions in this neighbourhood.
What are the top hotels in San Antonio?
Dumas Villas is one of San Antonio's most popular properties. Lock in a room here and you'll slumber peacefully knowing you're in capable hands.
How far in advance should I book my San Antonio holiday?
Search Expedia to compare international airfares ASAP. You can usually purchase a seat up to 12 months in advance. If you can't see your preferred air carrier, or you've left things to the last minute, don't stress. Cheap fares to San Antonio sometimes occur within weeks of the date of departure.
What does an Expedia San Antonio travel package include?
From airfares and hotels to rental cars, Expedia can help you put together a San Antonio package that's right for you. Holidaying for a few weeks? Check out a rental car, flight and hotel bundle. If your break is short, a hotel and flight deal may be more your style. Experiences can also be added once you've made your booking. Our holiday packages make it a cinch to plan and save.
What should I know before booking a San Antonio travel package?
So many places to explore, so many things to do. With a package, you can check more of them off your list. Bundle your hotels, flights and rental cars and get set to save.
Can I choose my airline with a San Antonio Expedia holiday package?
Yes — that's the beauty of an Expedia holiday package. You're in control. We have more than 550 airline partners all over the world, so you have lots of choice when putting together your San Antonio getaway.
If I'm not able to travel, can I cancel my San Antonio holiday package?
We totally get it — unexpected stuff happens. If you've booked a San Antonio holiday package and need to cancel or amend it, we can help. We recommend browsing our Customer Service Portal first for information. But generally, if you've booked your package within 24 hours, you may be able to cancel or amend your itinerary for free. If it's been longer than 24 hours, your hotel, airline or car rental company may impose a fee.

Things to do

Panama Canal Half Transit Experience

Panama Canal Partial Transit

฿4,657
per adult
84% of travellers recommend
Panama Canal Partial Transit
Panama City Visit an Indian town Embera and waterfall with lunch

Panama City Visit an Indian town Embera and waterfall with lunch

฿1,521
per adult
100% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
Panama City: POIN Swing Experience

Panama City: POIN Swing Experience

฿997
per adult
100% of travellers recommend
Panama City: POIN Swing Experience
See all activities in San Miguelito
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.