A densely packed urban area with numerous buildings and a prominent tower on a hill.

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Our top choices for Puerto Santa Ana hotels

1. Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.2 out of 10, Wonderful, (1,018 reviews)
"This is my top place everytime I go to Guayaquil,"
United States
maria
The price is ฿3,764
฿4,222 total
20 Sept - 21 Sept
Wyndham Guayaquil Puerto Santa Ana

2. River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
9.0 out of 10, Wonderful, (62 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is ฿3,499
฿3,532 total
26 Aug - 27 Aug
River View suites Puerto Santa Ana gye

3. Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (109 reviews)
"So clean and very nice people. I really recommend this facility, nice environment. My next trip lm booking in this apartment"
United States
Pedro
The price is ฿2,791
฿2,824 total
2 Sept - 3 Sept
Luxury Suites Riverfront GYE

4. Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador
4.0 star property
Las Peñas, 0.6 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (3 reviews)
"The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work. "
United States
Richard
The price is ฿11,736
฿13,048 total
26 Aug - 27 Aug
Hotel Río Guayas by Art Hotels Ecuador

5. Grand Hotel Guayaquil, Centro Histórico.

Grand Hotel Guayaquil, Centro Histórico.
4.0 star property
Rocafuerte, 2.2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,004 reviews)
"I enjoyed everything about this hotel."
United States
Maria Dorila
The price is ฿2,355
฿2,640 total
25 Sept - 26 Sept
Grand Hotel Guayaquil, Centro Histórico.

6. Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 0.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (143 reviews)
"Great place historical. Good service n breakfast. Great location"
United States
Mary Grant
The price is ฿1,941
฿2,167 total
27 Aug - 28 Aug
Mansión del Río

7. Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 2.1 km from Puerto Santa Ana
9.6 out of 10, Exceptional, (1,011 reviews)
"Very nice stay"
United States
Freddy
The price is ฿2,712
฿3,064 total
6 Sept - 7 Sept
Oro Verde Guayaquil

8. Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil
4.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (333 reviews)
"Great location."
United States
George S
The price is ฿1,963
฿2,208 total
4 Sept - 5 Sept
Ibis Styles El Malecon Guayaquil

9. Hotel Patrimonial by Greenfield

Hotel Patrimonial by Greenfield
3.5 star property
Downtown Guayaquil, 1.4 km from Puerto Santa Ana
8.4 out of 10, Very good, (162 reviews)
"The pool was enjoyable but going during the day so the water isn’t as cold."
United States
Julio
The price is ฿1,448
฿1,480 total
26 Aug - 27 Aug
Hotel Patrimonial by Greenfield

10. NCG SUITE ATARAZANA

NCG SUITE ATARAZANA
2.0 star property
La Atarazana, 0.8 km from Puerto Santa Ana
The price is ฿1,307
฿1,307 total
26 Aug - 27 Aug
NCG SUITE ATARAZANA

11. Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
3.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (1,011 reviews)
"Fantastic service and accommodations"
United States
Charles
The price is ฿3,173
฿3,572 total
25 Sept - 26 Sept
Holiday Inn Guayaquil Airport by IHG

12. Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,011 reviews)
"Best hotel and great location food amazing"
United States
Giselle
The price is ฿2,440
฿2,734 total
13 Sept - 14 Sept
Wyndham Garden Guayaquil

13. Hotel Marcelius

Hotel Marcelius
3.5 star property
Kennedy, 2.7 km from Puerto Santa Ana
8.4 out of 10, Very good, (254 reviews)
"👍"
United States
Marcos
The price is ฿2,124
฿2,369 total
28 Aug - 29 Aug
Hotel Marcelius

14. TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport
4.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,009 reviews)
"Great place to stay near the airport and just steps from Mall del Sol"
United States
Carlos
The price is ฿2,908
฿3,280 total
13 Sept - 14 Sept
TRYP by Wyndham Guayaquil Airport

15. Hotel del Parque

Hotel del Parque
4.5 star property
3.6 km from Puerto Santa Ana
9.8 out of 10, Exceptional, (133 reviews)
"Wonderful stay for our family of four!!! A+++++++ experience on all levels!!!"
United States
Brianna Meighan
The price is ฿14,015
฿15,417 total
7 Sept - 8 Sept
Hotel del Parque

16. Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil
5.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (123 reviews)
"Good staff...great location"
United States
ALBERTO
The price is ฿2,411
฿3,089 total
6 Sept - 7 Sept
Doubletree By Hilton Guayaquil

17. Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels
4.0 star property
Rocafuerte, 2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,007 reviews)
"Great Ecuadorian breakfast, super clean room."
United States
Jason
The price is ฿2,266
฿2,574 total
12 Sept - 13 Sept
Unipark by Oro Verde Hotels

18. Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil
3.5 star property
Kennedy, 2.5 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,010 reviews)
"Good staff, excelent food. I will defenetly will come back"
United States
Gloria E
The price is ฿2,614
฿2,924 total
11 Sept - 12 Sept
Courtyard by Marriott Guayaquil

19. Fortune Hotel

Fortune Hotel
3.0 star property
River City, 1 km from Puerto Santa Ana
7.6 out of 10, Good, (9 reviews)
"Is a great place the only problem is the disco bars outside the hotel "
United States
MARIA
The price is ฿1,375
฿1,407 total
26 Aug - 27 Aug
Fortune Hotel

20. Hotel Ramada

Hotel Ramada
3.0 star property
Downtown Guayaquil, 1.3 km from Puerto Santa Ana
8.0 out of 10, Very good, (410 reviews)
"Love the area where the hotel is located. Excellent breakfast. The pool area is beautiful where you can seat and relax "
United States
Sixto
The price is ฿2,058
฿2,091 total
26 Aug - 27 Aug
Hotel Ramada
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas for the activities you enjoy most.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Central Market while you're in town.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Policentro.

Simón Bolívar

When in Simón Bolívar, you can plan a visit to Mall del Sol Shopping Center and San Marino Mall, some noteworthy sights in the nearby area.

Top Puerto Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighbourhood that travellers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveller data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels should I expect to find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 90 Puerto Santa Ana hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to view the best deals in Puerto Santa Ana.
What is there to do around this Guayaquil neighbourhood?
Emporium by The Point, Santa Ana Garden and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.