Search Hotels in Puerto Isabela, Santo Domingo

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Our top choices for Puerto Isabela hotels

Catalonia Santo Domingo

Catalonia Santo Domingo
5.0 star property
Ciudad Universitaria, 5.7 km from Puerto Isabela
8.8 out of 10, Excellent, (1734)
"Beautiful hotel."
United States
Mibolange
The price is ฿3,269
฿4,185 total
includes taxes & fees
20 Dec - 21 Dec
Catalonia Santo Domingo

Hampton by Hilton Santo Domingo Airport

Hampton by Hilton Santo Domingo Airport
3.5 star property
27.6 km from Puerto Isabela
9.2 out of 10, Wonderful, (1000)
"Great hotel clean and close to airport"
United States
David
The price is ฿3,789
฿4,850 total
includes taxes & fees
30 Dec - 31 Dec
Hampton by Hilton Santo Domingo Airport

Radisson Hotel Santo Domingo

Radisson Hotel Santo Domingo
4.5 star property
Ensanche Naco, 3.5 km from Puerto Isabela
8.6 out of 10, Excellent, (1013)
"The Breakfast was fresh and nice"
United States
Jeudienne
The price is ฿2,479
฿3,174 total
includes taxes & fees
21 Dec - 22 Dec
Radisson Hotel Santo Domingo

Four Points by Sheraton Santo Domingo

Four Points by Sheraton Santo Domingo
4.0 star property
23.2 km from Puerto Isabela
8.2 out of 10, Very good, (182)
"Everything was really good for the price"
United States
Adrian
The price is ฿4,495
฿5,754 total
includes taxes & fees
26 Dec - 27 Dec
Four Points by Sheraton Santo Domingo

W&P Santo Domingo

W&P Santo Domingo
4.0 star property
Bella Vista, 6 km from Puerto Isabela
9.2 out of 10, Wonderful, (1158)
"The location, room, food and staff were fantastic! "
United States
Sandy
W&P Santo Domingo

Hotel Riazor

Hotel Riazor
3.5 star property
Ensanche Independencia, 5.4 km from Puerto Isabela
9.2 out of 10, Wonderful, (1010)
"Very good place to stay "
United States
Edward
Hotel Riazor

Luca Hotel by Heritage Residences Signature Collection

Luca Hotel by Heritage Residences Signature Collection
3.5 star property
Ciudad Colonial, 5.3 km from Puerto Isabela
9.2 out of 10, Wonderful, (701)
"Great staff, clean and comfortable An rooms"
United States
Asfaha
Luca Hotel by Heritage Residences Signature Collection

Renaissance Santo Domingo Jaragua Hotel & Casino

Renaissance Santo Domingo Jaragua Hotel & Casino
4.5 star property
Gascue, 5.6 km from Puerto Isabela
9.0 out of 10, Wonderful, (1002)
"Eevrything !! Had not stayed there in years and found it remodelled revamped and the staff… as always magnificent"
United States
Nelson Rivera
The price is ฿4,501
฿5,762 total
includes taxes & fees
2 Jan - 3 Jan 2026
Renaissance Santo Domingo Jaragua Hotel & Casino

El Embajador, a Royal Hideaway Hotel

El Embajador, a Royal Hideaway Hotel
5.0 star property
Bella Vista, 6.1 km from Puerto Isabela
9.2 out of 10, Wonderful, (1288)
"Great stay "
United States
Nelson
The price is ฿3,144
฿4,024 total
includes taxes & fees
31 Dec - 1 Jan 2026
El Embajador, a Royal Hideaway Hotel

Hotel Conde de Peñalba

Hotel Conde de Peñalba
3.0 star property
Ciudad Colonial, 5.3 km from Puerto Isabela
8.8 out of 10, Excellent, (829)
"great staff and location"
United States
Llency
The price is ฿2,087
฿3,301 total
includes taxes & fees
20 Dec - 21 Dec
Hotel Conde de Peñalba

Barceló Santo Domingo

Barceló Santo Domingo
4.0 star property
Miraflores, 3.7 km from Puerto Isabela
8.6 out of 10, Excellent, (1365)
"Great Food "
United States
Juana
The price is ฿1,768
฿2,263 total
includes taxes & fees
24 Dec - 25 Dec
Barceló Santo Domingo

Hodelpa Caribe Colonial

Hodelpa Caribe Colonial
3.5 star property
Ciudad Colonial, 5.3 km from Puerto Isabela
8.8 out of 10, Excellent, (1008)
"Perfect hotel great breakfast good services "
United States
Howard
The price is ฿2,914
฿3,730 total
includes taxes & fees
16 Jan - 17 Jan 2026
Hodelpa Caribe Colonial

Cataleya Hotel

Cataleya Hotel
3.0 star property
Ciudad Colonial, 5.1 km from Puerto Isabela
8.6 out of 10, Excellent, (329)
"Very clean and the staff very helpful I would stay there again. It’s also very safe area. I enjoy the breakfast. It was very nice."
United States
CARMEN
The price is ฿1,440
฿1,843 total
includes taxes & fees
23 Dec - 24 Dec
Cataleya Hotel

Hodelpa Nicolas de Ovando

Hodelpa Nicolas de Ovando
4.5 star property
Ciudad Colonial, 5.4 km from Puerto Isabela
9.2 out of 10, Wonderful, (1001)
"The food was excellent and well presented and the staff was pleasant and very helpful."
United States
William
The price is ฿6,473
฿8,285 total
includes taxes & fees
20 Dec - 21 Dec
Hodelpa Nicolas de Ovando

El Beaterio

El Beaterio
3.0 star property
Ciudad Colonial, 5.3 km from Puerto Isabela
9.2 out of 10, Wonderful, (420)
"A great stay in a spiritual space built in 1525. "
United States
Edgardo
The price is ฿3,192
฿4,086 total
includes taxes & fees
4 Jan - 5 Jan 2026
El Beaterio

Empyrean Art Deco

Empyrean Art Deco
3.0 star property
5 km from Puerto Isabela
9.2 out of 10, Wonderful, (84)
"Everything good!"
United States
milton
The price is ฿1,986
฿2,542 total
includes taxes & fees
6 Jan - 7 Jan 2026
Empyrean Art Deco

Sheraton Santo Domingo Hotel

Sheraton Santo Domingo Hotel
4.0 star property
Gascue, 5.6 km from Puerto Isabela
8.8 out of 10, Excellent, (1000)
"Quick stopover, clean rooms. Kind staff"
United Kingdom
Greg
The price is ฿3,395
฿4,345 total
includes taxes & fees
4 Jan - 5 Jan 2026
Sheraton Santo Domingo Hotel

Dominican Fiesta Hotel

Dominican Fiesta Hotel
4.0 star property
Los Cacicazgos, 9.4 km from Puerto Isabela
8.0 out of 10, Very good, (2581)
"The place is in a nice location , the hotel is beautiful and my favorite place was the pool. "
United States
Robert
The price is ฿2,609
฿3,339 total
includes taxes & fees
2 Jan - 3 Jan 2026
Dominican Fiesta Hotel

Mosquito Boutique Hotel Zona Colonial

Mosquito Boutique Hotel Zona Colonial
3.5 star property
Ciudad Colonial, 5.2 km from Puerto Isabela
8.8 out of 10, Excellent, (256)
"Amazing services on our stay. "
United States
Gilbert
The price is ฿2,798
฿3,581 total
includes taxes & fees
22 Dec - 23 Dec
Mosquito Boutique Hotel Zona Colonial

Santo Domingo Marriott Hotel Piantini - New Hotel

Santo Domingo Marriott Hotel Piantini - New Hotel
4.5 star property
Lope De Vega, 4.3 km from Puerto Isabela
9.4 out of 10, Exceptional, (250)
"Staff at check-in were extremely friendly. Excellent service. "
United States
Yvette
The price is ฿3,835
฿4,909 total
includes taxes & fees
26 Dec - 27 Dec
Santo Domingo Marriott Hotel Piantini - New Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Puerto Isabela

Find the best Puerto Isabela areas for the activities you enjoy most.

Zona Colonial

Zona Colonial is popular for its abundant dining options, and if you're looking for more to see and do, you might think about a trip to Calle El Conde or Santa Maria la Menor Cathedral.

Piantini

Unique features of Piantini include the shopping and restaurants. Make a stop by Blue Mall or Acropolis Center while you're exploring the area.

Downtown Santo Domingo

Consider exploring the abundant dining options in Downtown Santo Domingo. If sightseeing is on the list, Acropolis Center is a top attraction. Hop on the metro at Freddy Beras Goico Station or Juan Ulises Garcia Station to see more of the area.

Ciudad Colonial

If you're spending some time in Ciudad Colonial, Calle El Conde and Santa Maria la Menor Cathedral are top sights worth seeing.

Bella Vista

While there might not be top attractions in Bella Vista, you can explore the larger area and discover places like Acropolis Center and Bella Vista Mall.

Top Puerto Isabela Hotel Reviews

Frequently asked questions

What is Puerto Isabela like?
Travellers will be sure to find plenty to entertain them in Santo Domingo's Puerto Isabela neighbourhood. Consider a visit to National Zoological Park as part of your Puerto Isabela travel plans.
If I need to cancel my hotel reservation in Puerto Isabela, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to view the best deals available in Puerto Isabela.
What are the top things to see and do in Puerto Isabela?
National Zoological Park is an attraction you might want to check out while you're in Puerto Isabela. When you're sightseeing in Santo Domingo, Quisqueya Stadium and Sambil Santo Domingo are also worth a stop.
How can I get around Puerto Isabela and the greater Santo Domingo area?
Ready to get out and explore the city? Maximo Gomez Station is the closest metro station.