Penrose Packages (Flight + Hotel)

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Where to stay in Penrose

Find the best Penrose areas and neighborhoods for the activities you enjoy most. Learn more about Penrose
A public park with a fountain featuring bronze sculptures of mythological figures, surrounded by trees and a large building in the background.

Downtown St. Louis

4 out of top 10 points of interest in this area

Gourmet restaurants beloved sports teams and top sights from Gateway Arch National Park to Kiener Plaza – discover Downtown St. Louis, a destination also famous for its historic sites.

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The illuminated Gateway Arch at night with a city skyline in the background.

Clayton

1 out of top 10 points of interest in this area

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

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A street with parked cars, a building with a sign reading "Brennan's", and a tree in front.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

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A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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Top hotels in Penrose

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
฿3,088
฿3,605 total
11 Oct - 12 Oct
includes taxes & fees
8.8/10 Excellent! (3,451 reviews)
"Staff was amazing.Breakfast was too. We made it a point to go get omelets every morning. She was pushing them off the line hot n fresh. Definitely will be my spot when I come back in January."

Reviewed on 28 Sept 2026

Clayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
฿4,477
฿5,280 total
2 Oct - 3 Oct
includes taxes & fees
Hyatt Regency St. Louis at The Arch
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
฿3,005
฿3,537 total
4 Oct - 5 Oct
includes taxes & fees
9.2/10 Wonderful! (3,274 reviews)
"Great value. Loved it. A little more upscale at a budget price."

Reviewed on 29 Sept 2026

Pear Tree Inn St. Louis Airport
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Penrose attractions

Julia Davis Branch Library

You can enjoy some culture when you stop by Julia Davis Branch Library in St. Louis.
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Things to do

The Gateway Arch National Park & Museum

StL's Signature "Sights and Bites" - Private Tour in St. Louis

฿5,740
per adult
StL's Signature "Sights and Bites" - Private Tour in St. Louis
Self Guided Walking & Driving Audio Tour St. Louis

Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP

฿492
per traveller
Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP
St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

฿787
per adult
100% of travellers recommend
St. Louis Ghost Tour: Sinister Sins & Shadows
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.