
Panama City Packages (Flight + Hotel)
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Save up to ฿4,531 when you book a flight and hotel together*
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Where to stay in Panama City
Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City

Casco Viejo
3.5/5(3 area reviews)
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.
Top hotels in Panama City

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is ฿3,256 per night from 31 Aug to 1 Sept
฿3,256
฿3,582 total
31 Aug - 1 Sept
includes taxes & fees
9/10 Wonderful! (4,208 reviews)
"The location was amazing and hotel was amazing however I was very disappointed that the pool was closed for our entire trip."
Reviewed on 26 Aug 2025

Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Fully refundableReserve now, pay when you stay
The price is ฿2,614 per night from 31 Aug to 1 Sept
฿2,614
฿2,876 total
31 Aug - 1 Sept
includes taxes & fees
9/10 Wonderful! (441 reviews)
"Pool area was Amazing! The male bartender by the gym was OUTSTANDING!!"
Reviewed on 27 Aug 2025

Sheraton Grand Panama
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is ฿4,329 per night from 12 Sept to 13 Sept
฿4,329
฿4,762 total
12 Sept - 13 Sept
includes taxes & fees
8.4/10 Very Good! (936 reviews)
"Everyone was very nice and accommodating. The staff was primarily bilingual, offered to help with anything needed, and offered water bottles as part of the service."
Reviewed on 21 Aug 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Panama Canal Railway
Enjoy an outing to Panama Canal Railway during your stay in Ancon. Stroll along the seaside or visit the shops in this culturally rich area.
What to do in Panama City

Day Tour in San Blas Islands All Included Visiting 4 Islands
฿4,836
per adult
94% of travellers recommend

Panama City Visit an Indian town Embera and waterfall with lunch
฿1,623
per adult
96% of travellers recommend
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Flights
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.