Grand Isle Travel Guide

Port St. Joe

A sunset over a body of water with a bridge in the background.

Things to do

Port St Joe Inshore Fishing Charters

Port St Joe Inshore Fishing Charters

฿27,058
per traveller
Port St Joe Inshore Fishing Charters
See all activities in Port St. Joe

Top hotels in Grand Isle

Comfort Suites

Comfort Suites

2.5 out of 5
264 N Tyndall Pkwy Panama City FL
The price is ฿2,544 per night from 15 Nov to 16 Nov
฿2,544
฿2,750 total
15 Nov - 16 Nov
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. ...
Comfort Suites
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

2.5 out of 5
5627 E Highway 22 State Route Panama City FL
The price is ฿2,641 per night from 15 Nov to 16 Nov
฿2,641
฿2,854 total
15 Nov - 16 Nov
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. ...
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
MainStay Suites Port Saint Joe South

MainStay Suites Port Saint Joe South

2.5 out of 5
3951 E Highway 98 Port St. Joe FL
The price is ฿3,890 per night from 1 Nov to 2 Nov
฿3,890
฿4,356 total
1 Nov - 2 Nov
includes taxes & fees
Stay at this business-friendly hotel in Port St. Joe. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. ...
MainStay Suites Port Saint Joe South
Extended Stay America Select Suites - Panama City - Callaway

Extended Stay America Select Suites - Panama City - Callaway

2.5 out of 5
902 N Tyndall Parkway Panama City FL
The price is ฿2,196 per night from 1 Nov to 2 Nov
฿2,196
฿2,373 total
1 Nov - 2 Nov
includes taxes & fees
Stay at this hotel in Panama City. Enjoy free Wi-Fi, free parking and laundry facilities. Popular attractions Southwood Shopping Center and Saint Andrews Shopping ...
Extended Stay America Select Suites - Panama City - Callaway
The Port Inn - Port St Joe, an Ascend Collection Hotel

The Port Inn - Port St Joe, an Ascend Collection Hotel

3.5 out of 5
501 Monument Ave. Port St. Joe FL
The price is ฿4,971 per night from 1 Nov to 2 Nov
฿4,971
฿5,567 total
1 Nov - 2 Nov
includes taxes & fees
Stay at this hotel in Port St. Joe. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...
The Port Inn - Port St Joe, an Ascend Collection Hotel
Driftwood Inn

Driftwood Inn

2 out of 5
2105 U.S. 98 Mexico Beach FL
The price is ฿6,001 per night from 26 Oct to 27 Oct
฿6,001
฿6,721 total
26 Oct - 27 Oct
includes taxes & fees
Stay at this beach hotel in Port St. Joe. Enjoy free Wi-Fi, free parking and a beach locale. Popular attractions Mexico Beach Park and Mexico Beach are located ...
9.6/10 Exceptional! (130 reviews)
"Wonderful place to relax. Hotel is so pretty and their suite room is so spacious. Beautiful beach, very quiet and not crowded. Perfect peaceful getaway spot."

Reviewed on 18 Oct 2026

Driftwood Inn
See all 2,282 properties in Grand Isle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Grand Isle

Find the best Grand Isle areas for the activities you enjoy most.
A marina at sunset with boats docked and a wooden pier.
Photo by Russell Hewatt
Open Photo by Russell Hewatt

Downtown Port St. Joe

If you're spending some time in Downtown Port St. Joe, Port Saint Joe City Hall and Constitution Convention Museum State Park are top sights worth seeing.

A white house with a black roof, a white lighthouse with a black top, and a calm lake with purple flowers in the foreground.

Cape Breezes

Cape Breezes might not have many top sights, but T.H. Stone Memorial St. Joseph Peninsula State Park and St. Joseph Peninsula State Park are two attractions nearby that you can check out.

A beach with driftwood formations at sunset.

Gulf Aire

While Gulf Aire may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Saint Joe Beach and Mexico Beach.

A sandy beach with calm waters and a large cloud in the sky.

Waterside Village

While Waterside Village isn't home to many top sights, Mexico Beach Marina and Mexico Beach are some notable places to visit nearby.

A coastal landscape with tall grasses, a palm tree, and a sunset over the water.

Palms

While there might not be top attractions in Palms, you can explore the larger area and discover places like Mexico Beach and Mexico Beach Marina.

Grand Isle Travel Guide