A pier extending into calm waters with a small boat docked at the end.

Find hotels in Panacea, FL from ฿3,397

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Check prices for these dates

Tonight
26 Aug - 27 Aug
Tomorrow
27 Aug - 28 Aug
This weekend
28 Aug - 30 Aug
Next weekend
4 Sep - 6 Sep

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Our top choices for Panacea hotels

A pink door with a window, set in a corrugated metal exterior with wooden trim.
A wooden bench in a natural setting with trees and a body of water in the background.
A kitchen with white cabinets, a stainless steel refrigerator, a microwave, a stove, and a sink. There are wooden shelves above the counter and a window with a view.
A kitchen with a wooden countertop, a built-in sink, and a trash can.

1. The Panacea Motel

The Panacea Motel
Panacea
United States
Michelle
฿3,894
฿4,342 total
includes taxes & fees
27 Aug - 28 Aug
The Panacea Motel
A fountain with a dolphin statue in a courtyard, surrounded by buildings with arched windows and a pool with blue mosaic tiles.
A hotel with a covered patio, outdoor seating, and a central pathway leading to the entrance.
A hotel lobby with a coffee bar, seating area, and a clock on the wall.
A modern hotel lobby with a sofa, armchairs, a desk, and a TV.

2. Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
Crawfordville
United States
Lydia
฿3,635
฿4,053 total
includes taxes & fees
22 Sept - 23 Sept
Best Western Wakulla Inn & Suites
A spacious indoor area with tiled flooring, multiple tables and chairs, a stone fireplace, and a glass door entrance.
A hotel room with a bed, a desk, a chair, a small table with a vase, a trash bin, and a wooden door.
A stone fireplace with a painting above it, wooden walls, a dining area with chairs, and a view of parked cars through large windows.

3. Wildwood Inn

Wildwood Inn
Crawfordville
United States
Kizzy
฿3,902
฿4,481 total
includes taxes & fees
31 Aug - 1 Sept
Wildwood Inn
A spacious lobby with leather sofas, a coffee table, and a large window with arched frames.
A spacious dining area with multiple tables and chairs, large windows, and hanging chandeliers.
A courtyard with a central fountain, surrounded by well-maintained hedges and trees.
A spacious lobby with high ceilings, ornate ceiling decorations, and large windows.

4. The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
Crawfordville
United States
Sherry
฿3,695
฿4,120 total
includes taxes & fees
31 Aug - 1 Sept
The Lodge at Wakulla Springs
A bar area with a long counter, stools, and a variety of bottles and glasses.
A living room with a sofa set, a television, and a ceiling fan.
A multi-story hotel with a reflective water body in front, surrounded by greenery and a golf course.
A swimming pool with lounge chairs, palm trees, and a clear blue sky.

5. St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
Carrabelle
United States
Mike
฿4,696
฿6,444 total
includes taxes & fees
2 Sept - 3 Sept
St James Bay Golf & Pickleball Resort
A hotel room with two beds, a nightstand, a lamp, and a bathroom visible through an open door.
A hotel room with a large bed, two bedside tables, a desk with a chair, and a lamp.
A motel with a single-story structure, a covered parking area, and a palm tree in front.
A motel with a row of rooms, a staircase, and a parking area.

6. Franklin Inn

Franklin Inn
Carrabelle
United States
Melynda
฿3,074
฿3,397 total
includes taxes & fees
2 Sept - 3 Sept
Franklin Inn
A covered patio with a table and chairs, a wooden ceiling fan, and a view of the surrounding greenery.
The Carrabelle Hotel with a white exterior, multiple balconies, and surrounded by tropical vegetation.
A bedroom with a wooden four-poster bed, a ceiling fan, a bookshelf, and a wall-mounted lamp.
A yellow door with a window, a potted plant, a white wall-mounted light fixture, and a staircase with yellow curtains.

7. The Old Carrabelle Hotel

The Old Carrabelle Hotel
Carrabelle
United States
David
฿3,442
฿3,803 total
includes taxes & fees
3 Sept - 4 Sept
The Old Carrabelle Hotel
A marina with boats docked, a small building, and a clear sky.
A spacious room with a pool table, a billiards table, and a dining area with chairs and a table.
A pool area with a table and chairs, a building with doors, and a palm tree.
A spacious room with a pool table, a round dining table with chairs, and large windows offering a view of a body of water.

8. The Moorings Hotel and Marina

The Moorings Hotel and Marina
Carrabelle
United States
Tina
฿5,900
฿6,519 total
includes taxes & fees
1 Sept - 2 Sept
The Moorings Hotel and Marina
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Stay near popular Panacea attractions

Alligator Point Beach

8.8/10 (10 reviews)
Escape to this pristine stretch of old coastal Florida with white sands and shallow, clear waters. Spot dolphins and sea turtles while enjoying the serenity of an undeveloped shoreline.
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Bald Point State Park

8.6/10 (20 reviews)
Where Ochlockonee Bay meets Apalachee Bay, this coastal park showcases diverse ecosystems from beaches to pine flatwoods. Spot migrating raptors and monarch butterflies while hiking through pristine natural habitats.
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Mashes Sand Beach

8.8/10 (3 reviews)
Mashes Sands Beach offers serene shallow waters and expansive sandbars perfect for peaceful exploration. Wade through the tea-colored Gulf waters while spotting hermit crabs and enjoying spectacular sunset views.
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Wilson Beach

Wilson Beach offers a serene Gulf Coast escape with pristine shores and gentle waves far from tourist crowds. Bring supplies and enjoy peaceful beachcombing along this unspoiled natural sanctuary.
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Panacea Springs

Once a popular health resort, these historic mineral springs were believed to possess healing properties in the early 1900s. Explore the remnants of spa structures while imagining the therapeutic rituals of a bygone era.
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Public Beach Access

Mashes Sands Beach features tranquil white-sand shores and shallow waters ideal for families. Wade in the gentle surf, cast a fishing line, or enjoy a peaceful picnic away from tourist crowds.
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Silver Lake

Swim in crystal-clear waters along a pristine 250-foot white sand beach surrounded by longleaf pines. The mile-long interpretive trail offers peaceful wildlife encounters with bald eagles and turtles.
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Alligator Harbor Aquatic Preserve

Explore the great outdoors at Alligator Harbor Aquatic Preserve, a lovely green space in Panacea. Stroll along the beaches in this relaxing area or seek out the fishing spots.
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Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

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A sunset over a calm body of water with silhouettes of birds flying and a distant tree line.

Top Panacea Hotel Reviews

More cheap stays in Panacea

Franklin Inn

Franklin Inn

1589 US-98 Carrabelle FL
฿3,074
฿3,397 total
2 Sept - 3 Sept
includes taxes & fees
7.8/10 Good! (507 reviews)
Franklin Inn
The Old Carrabelle Hotel

The Old Carrabelle Hotel

201 Tallahassee St Carrabelle FL
฿3,442
฿3,803 total
3 Sept - 4 Sept
includes taxes & fees
9.6/10 Exceptional! (43 reviews)
The Old Carrabelle Hotel
Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites

3292 Coastal Hwy 98 Crawfordville FL
฿3,635
฿4,053 total
22 Sept - 23 Sept
includes taxes & fees
8.8/10 Excellent! (1,000 reviews)
Best Western Wakulla Inn & Suites
The Panacea Motel

The Panacea Motel

1545 Coastal Hwy Panacea FL
฿3,894
฿4,342 total
27 Aug - 28 Aug
includes taxes & fees
The Panacea Motel
The Moorings Hotel and Marina

The Moorings Hotel and Marina

1000 Hwy 98 Carrabelle FL
฿5,900
฿6,519 total
1 Sept - 2 Sept
includes taxes & fees
The Moorings Hotel and Marina
Cozy Waterfront 'island House' on Live Oak Island!

Cozy Waterfront 'island House' on Live Oak Island!

Crawfordville FL
Get ratesCozy Waterfront 'island House' on Live Oak Island!

Frequently asked questions

If I need to cancel my hotel reservation in Panacea, will I receive a refund?
Yes, the majority of hotel bookings are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.
What's the best dog-friendly place to stay in Panacea?
The Panacea Motel is a top dog-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.
How is it to stay in Panacea?
Nature enthusiasts will enjoy exploring Panacea, and many visitors will definitely appreciate the beaches and seafood restaurants. The relaxing and secluded setting also entices those visiting the city. In Panacea, there are 231 hotels and other accommodation options to choose from. Find out more about Panacea.
What are the top places to visit in Panacea?
Natural beauty is on display at Mashes Sand Beach, Alligator Point Beach and Bald Point State Park. Dolphin viewing is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your itinerary are Wilson Beach and Public Beach Access. Take a look at what more there is to see and do in Expedia's Panacea guide.
What's the seasonal weather in Panacea?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. The rainiest months in Panacea are August, July, June and September, with each month seeing an average of 201 mm of rainfall.

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