A city skyline with high-rise buildings and a bridge over a body of water.

Search Gay-Friendly Hotels in Otay Mesa

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Otay Mesa Gay-Friendly Hotels

Our top choices for Otay Mesa LGBT-friendly hotels

A modern interior with a long table and blue chairs, large windows with a view of palm trees and parked vehicles outside.

1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.4 out of 10, Very good, (1,920 reviews)
"Good staff, very good breakfast, rooms where nice and clean"
United States
Michael
The price is ฿4,359
฿4,958 total
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
An outdoor seating area with fire pit, lounge chairs, and tables, adjacent to a building with large windows and a brick facade.

2. Hampton Inn Chula Vista Eastlake

Hampton Inn Chula Vista Eastlake
2.5 star property
Chula Vista
9.2 out of 10, Wonderful, (1,002 reviews)
"Staff very friendly and accommodating, hotel was clean and bright. Breakfast was excellent"
United States
Maggie
The price is ฿5,705
฿6,286 total
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn Chula Vista Eastlake
A spacious lobby with a flat-screen TV, a fireplace, and comfortable seating areas.

3. Residence Inn by Marriott San Diego Chula Vista

Residence Inn by Marriott San Diego Chula Vista
3.0 star property
Otay Ranch
9.4 out of 10, Exceptional, (627 reviews)
"Excelente todo"
Mexico
jensen karel
The price is ฿6,462
฿7,121 total
includes taxes & fees
1 Nov - 2 Nov
Residence Inn by Marriott San Diego Chula Vista
A Holiday Inn Express building with a prominent entrance, palm trees, and a clear sky.

4. Holiday Inn Express San Diego South - Chula Vista by IHG

Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
Chula Vista
9.4 out of 10, Exceptional, (1,596 reviews)
"Was a great stay!!"
United States
Taylor
The price is ฿5,921
฿6,513 total
includes taxes & fees
5 Nov - 6 Nov
Holiday Inn Express San Diego South - Chula Vista by IHG
A breakfast bar with La Quinta branding, a coffee machine, and a waffle display.

5. La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
Chula Vista
8.8 out of 10, Excellent, (1,759 reviews)
"Enjoyed our stay"
United States
Nuwan
The price is ฿3,477
฿3,825 total
includes taxes & fees
1 Nov - 2 Nov
La Quinta Inn by Wyndham San Diego Chula Vista
A swimming pool with palm trees and a mountain in the background.

6. Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
El Cajon
9.4 out of 10, Exceptional, (2,176 reviews)
"Loved the stay for my birthday!"
United States
Alexza
The price is ฿3,306
฿4,039 total
includes taxes & fees
15 Oct - 16 Oct
Sycuan Casino Resort
A hotel with a large swimming pool, multiple water slides, and a well-lit outdoor area with lounge chairs and umbrellas.

7. Gaylord Pacific Resort & Convention Center

Gaylord Pacific Resort & Convention Center
4.0 star property
Chula Vista
8.8 out of 10, Excellent, (683 reviews)
"The resort was very fun"
United States
Rabb
The price is ฿10,361
฿13,350 total
includes taxes & fees
23 Oct - 24 Oct
Gaylord Pacific Resort & Convention Center
A hotel room with a large bed, a desk, a chair, a painting, and a view of the city.

8. Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
National City
9.2 out of 10, Wonderful, (4,185 reviews)
"Great property and we enjoyed the stay"
United States
Suresh
The price is ฿5,100
฿5,620 total
includes taxes & fees
25 Oct - 26 Oct
Best Western Plus Marina Gateway Hotel
A balcony with a view of the beach, palm trees, and a parking area.

9. Los Bungalows

Los Bungalows
2.5 star property
Seacoast
8.2 out of 10, Very good, (566 reviews)
"the property was in a great"
United States
Jennifer
The price is ฿5,609
฿6,394 total
includes taxes & fees
12 Oct - 13 Oct
Los Bungalows
A high-rise hotel with multiple floors, a prominent sign at the top, and a well-lit facade.

10. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,244 reviews)
"Great for traveling families."
United States
Veronica Dangerfield
The price is ฿6,237
฿7,231 total
includes taxes & fees
25 Oct - 26 Oct
Marriott Vacation Club®, San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Otay Mesa Hotel Reviews

Frequently asked questions

How do I find gay-friendly accommodation in Otay Mesa?
Consider this your open invitation to pack your bags and find LGBTQ-friendly hotels in Otay Mesa on Expedia. People like Otay Mesa for its shopping and restaurants.
What is the top LGBTQ-friendly hotel in Otay Mesa?
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi.
What should I do while I'm visiting Otay Mesa?
During your trip, get out and enjoy everything Otay Mesa has to offer. You and your travelling companions may want to visit San Diego Zoo, San Ysidro Border Crossing and Petco Park. While you're here, capture some great memories of your trip with stops at Port of San Diego and Marine Corps Recruit Depot.
What is a gay-friendly hotel in Otay Mesa?
LGBTQ-friendly hotels, also known as gay-friendly hotels, welcome all travellers who identify as LGBTQIA+. We have worked with the International Gay and Lesbian Travel Association (IGLTA) to compile a selection of gay-friendly hotels worldwide. In Otay Mesa, hotels affiliated with IGLTA operate in a spirit of inclusiveness, prioritising a diverse environment in which guests are welcomed, respected and not obliged to declare or hide their sexual orientation.
What can I expect from a gay-friendly hotel in Otay Mesa?
Stay at a gay-friendly hotel in Otay Mesa and you won't have to hide or your sexuality or your gender identity when you check in. Some of Expedia's LGBTQ-friendly hotels go the extra mile and offer concierge services that provide information about nearby LGBTQ restaurants and local events.

Explore a world of travel with Expedia