Find hotels in New Madrid, MO from ฿2,023

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Our top choices for New Madrid hotels

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (472 reviews)
"Everything great "
United States
Jayla
The price is ฿2,251
฿2,583 total
includes taxes & fees
20 Mar - 21 Mar
Reelfoot Lake Inn

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.2 out of 10, Very good, (51 reviews)
"Room was clean and fairly priced. "
United States
Mickey
The price is ฿2,162
฿2,470 total
includes taxes & fees
3 Apr - 4 Apr
Super 8 By Wyndham Marston

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (63 reviews)
"Nice quiet hotel "
United States
Steven
The price is ฿3,261
฿3,693 total
includes taxes & fees
22 Mar - 23 Mar
Fairfield Inn & Suites by Marriott Sikeston

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (751 reviews)
"The staff was great very helpful and friendly "
United States
Javier
New Orleans Inn Portageville

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (449 reviews)
"Stay was excellent "
United States
Kourtney
The price is ฿3,003
฿3,401 total
includes taxes & fees
22 Mar - 23 Mar
Holiday Inn Express & Suites Sikeston Southwest by IHG

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (502 reviews)
"Great stay"
United States
grant
The price is ฿2,966
฿3,358 total
includes taxes & fees
12 Apr - 13 Apr
Hampton Inn Sikeston

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (14 reviews)
"This hotel was great. Good location. Awesome staff. Hopefully I get the opportunity to stay here again."
United States
Jason
The price is ฿3,810
฿4,314 total
includes taxes & fees
22 Mar - 23 Mar
TownePlace Suites by Marriott Sikeston

Travel Inn

Travel Inn
2.5 star property
Marston
6.0 out of 10, (118 reviews)
"Had a great time loved it "
United States
Shyianne
The price is ฿1,771
฿2,023 total
includes taxes & fees
29 Mar - 30 Mar
Travel Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular New Madrid attractions

Learn more about New Madrid

The New Madrid Historical Museum reveals the dramatic storey of the 1811-1812 earthquakes that changed the course of the Mississippi River. Enjoy peaceful fishing at Donaldson Point Conservation Area or take a sunset river cruise to spot bald eagles along the mighty Mississippi.

Mississippi River Walk at New Madrid.  A magnificent view of the Mississippi river from atop of the levee.  A steamboat is docked down river. .

Top New Madrid Hotel Reviews

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Frequently asked questions

Where is the best place for a stay in New Madrid?
Hampton Inn Sikeston, located 18.9 mi (30.4 km) from the heart of New Madrid, is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Reelfoot Lake Inn and Holiday Inn Express & Suites Sikeston Southwest by IHG. See all available top hotels, or vacation rentals in New Madrid.
If I need to cancel my hotel reservation in New Madrid, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in New Madrid.
What is staying in New Madrid like?
Visitors can enjoy all that New Madrid has to offer, including the parks and museums. There are 57 hotels and other accommodation options in the surrounding area. Find out more about New Madrid.
What should I do while I'm visiting New Madrid?
Cultural venues include New Madrid Historical Museum and Hunter-Dawson State Historic Site. A couple of additional sights to add to your itinerary are Mississippi River and River Ridge Winery. Take a look at what more there is to see and do in Expedia's New Madrid guide.
What's the seasonal weather in New Madrid?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 6°C. Average annual precipitation for New Madrid is 1537 mm.