New Madrid Travel Guide

Tourist Guide

A cannon on a brick platform by a river, with a steamboat in the background.
A river with a dam, surrounded by greenery and a clear sky.
A tree-lined landscape with a river and fields.
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 out of 5
115 Hospitality Dr Sikeston MO
The price is ฿3,063 per night from 2 Aug to 3 Aug
฿3,063
฿3,468 total
2 Aug - 3 Aug
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (479 reviews)
"Nice!"

Reviewed on 10 Jul 2026

Holiday Inn Express & Suites Sikeston Southwest by IHG
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
The price is ฿3,542 per night from 23 Jul to 24 Jul
฿3,542
฿4,011 total
23 Jul - 24 Jul
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...
9/10 Wonderful! (592 reviews)
"My 21 year old son stayed at this Hampton Inn on his way back to college in IL. He enjoyed the gym, the indoor pool, the large selection of breakfast items, and the close proximity to I-55. The room was clean and the staff was friendly, even to a 21 year old young man traveling alone. Thank you for ..."

Reviewed on 15 Jul 2026

Hampton Inn Sikeston
New Orleans Inn Portageville

New Orleans Inn Portageville

2.5 out of 5
600 US-61 Portageville MO
The price is ฿1,899 per night from 19 Jul to 20 Jul
฿1,899
฿2,050 total
19 Jul - 20 Jul
includes taxes & fees
Stay at this motel in Portageville. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in their ...
New Orleans Inn Portageville
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Prime Fishing & Boating: Tiptonville Home

Prime Fishing & Boating: Tiptonville Home

3 out of 5
Tiptonville TN
Stay at this cottage in Tiptonville. Enjoy free parking and air conditioning. Popular attractions Tiptonville Public Library and Lake County Recreational Park ...
Prime Fishing & Boating: Tiptonville Home
Boat Dock on Reelfoot Lake: Tiptonville Retreat

Boat Dock on Reelfoot Lake: Tiptonville Retreat

3 out of 5
Tiptonville TN
Stay at this cottage in Tiptonville. Enjoy free parking, a marina and balconies. Popular attractions Grassy Island and Horse Island are located nearby.
Boat Dock on Reelfoot Lake: Tiptonville Retreat
Close to Reelfoot Lake! Dog-friendly Retreat

Close to Reelfoot Lake! Dog-friendly Retreat

2.5 out of 5
Tiptonville TN
Stay at this apartment in Tiptonville. Enjoy air conditioning. Popular attractions Campbell's Point and Reelfoot Lake State Park are located nearby.
Close to Reelfoot Lake! Dog-friendly Retreat
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular New Madrid attractions

New Madrid Historical Museum

8.2/10 (36 reviews)
You can study the exhibits at New Madrid Historical Museum, a museum with a storied past, during your travels to New Madrid. Amble around the area's parks or experience its museums.
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