The Best Hotels Closest to Murphy Island in Palmyra - 2026 Updated Prices

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Our top choices for Murphy Island hotels

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

An indoor swimming pool with a lifeguard chair, poolside chairs, and a table with chairs.

A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.

A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.

1. Sleep Inn & Suites Hannibal West

6.1 km from Murphy Island

Patricia

฿3,624

฿4,216 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.

A multi-level indoor pool area with a clear pool, multiple balconies, and a covered seating area.

A multi-level indoor pool area with a visible water slide, a towel rack, and a notice board.

2. Best Western On The River

4.7 km from Murphy Island

Raymond

฿3,635

฿4,193 total

includes taxes & fees

20 Sept - 21 Sept

A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.

A wooden table with a bottle of champagne, two glasses, and scattered rose petals.

A historic building with a stone facade and multiple windows, featuring a sign about Tom Sawyer's fence.

A compact kitchen with a refrigerator, microwave, and sink.

3. Riverside Inn Hannibal

4.9 km from Murphy Island

Jack

฿5,322

฿7,282 total

includes taxes & fees

14 Sept - 15 Sept

An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.

A hotel entrance with a central fountain, large columns, and a clear sky.

A lobby with leather sofas, a fireplace, a flat-screen TV, and a reception desk.

A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.

4. Quality Inn & Suites Hannibal West

6 km from Murphy Island

Tom

฿2,656

฿3,091 total

includes taxes & fees

4 Oct - 5 Oct

A wooden staircase with a handrail, a small table with a lamp, and a chair in a room with a door and windows.

A dining area with a table set for four, surrounded by wooden chairs. A chandelier hangs above the table, and a lamp provides additional lighting.

A large, two-story house with a porch and a sign indicating 'ONE WAY'.

A fireplace with decorative elements, framed pictures, and a vase of red flowers.

5. Garden House Bed and Breakfast

4.9 km from Murphy Island

Edward

฿3,062

฿3,532 total

includes taxes & fees

14 Sept - 15 Sept

A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

A swimming pool with lounge chairs and a covered seating area.

A compact kitchen with white cabinets, a microwave, a coffee maker, and a sink.

A modern living room with a grey sofa, a white armchair, a coffee table, and a patterned rug. There is a kitchen in the background with white cabinets and a black door.

6. Lighthouse Inn & Suites

4.3 km from Murphy Island

Kari

฿5,932

฿6,842 total

includes taxes & fees

14 Sept - 15 Sept

A hotel room with a bed, a sofa, a desk, and a lamp.

A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.

An indoor swimming pool with wooden walls, a tiled floor, and a sign indicating no diving is allowed.

A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.

7. Comfort Inn & Suites - Hannibal

7.3 km from Murphy Island

Melanie

฿2,524

฿3,011 total

includes taxes & fees

20 Sept - 21 Sept

A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.

A coffee station with a coffee machine, cups, and a sign that says "RISE & SHINE."

A spacious lobby with a fireplace, leather sofas, a coffee table, and a large window with blinds.

A building with a covered entrance and a sign indicating a clearance height of 13 feet.

8. Motel 6 Hannibal, MO

5.7 km from Murphy Island

Neal

฿1,917

฿2,211 total

includes taxes & fees

15 Sept - 16 Sept

A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.

A long hallway with a patterned carpet, wooden paneling on the walls, and a ceiling light.

A modern dining area with round tables and chairs, a flat-screen TV mounted on the wall, and a brick accent wall.

A hotel room with a large bed, a desk with a chair, a window with curtains, and a wall-mounted artwork.

9. Super 8 by Wyndham Hannibal

5.6 km from Murphy Island

Betty

฿2,041

฿2,354 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with two beds, a wooden headboard, a nightstand with a phone and lamp, and a large sunset painting above the beds.

A reception area with a marble counter, a 'Days Inn' sign, and a welcome mat.

A corner kitchenette with a refrigerator, coffee maker, and food display.

A hotel with a covered entrance, a parking lot, and a clear sky.

10. Days Inn by Wyndham Hannibal

7.4 km from Murphy Island

PERRY

฿1,851

฿2,135 total

includes taxes & fees

20 Sept - 21 Sept

A large indoor swimming pool with multiple levels of balconies, surrounded by seating areas and potted plants.

A clean, modern reception area with a reception desk, a clock, and a potted plant.

A modern building with a red awning, a parking lot, and a sign indicating an entrance.

A kitchen with wooden cabinets, a granite countertop, and various food items and kitchen appliances.

11. Howard Johnson BY Wyndham Hannibal

7.5 km from Murphy Island

Debbie

฿2,009

฿2,334 total

includes taxes & fees

14 Sept - 15 Sept

An indoor swimming pool with a tiled ceiling, multiple levels with windows, and seating areas around the pool.

A hotel room with a bed, a desk with a chair, a television, and a desk lamp.

A kitchen with a granite countertop, wooden cabinets, and a herringbone-patterned floor.

12. Baymont by Wyndham Hannibal

7.4 km from Murphy Island

brian

฿1,742

฿2,023 total

includes taxes & fees

15 Sept - 16 Sept

A spacious living area with a large bed, a dining table, and a brick wall.

A storefront with a red and gray facade, large windows, and various beer advertisements.

A rooftop terrace with a brick wall, a metal railing, and a table with chairs.

A kitchen with wooden cabinets, a stainless steel stove, a dishwasher, and a brick wall.

13. Deck + River View: Loft in Downtown Hannibal

4.9 km from Murphy Island

฿4,561

฿8,759 total

includes taxes & fees

14 Sept - 15 Sept

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Compare popular hotels close to Murphy Island

Property	Property class	Guest rating
Sleep Inn & Suites Hannibal West	9.6 Exceptional 1,003 reviews	View
Best Western On The River	8.8 Excellent 1,007 reviews	View
Riverside Inn Hannibal	9.6 Exceptional 196 reviews	View
Quality Inn & Suites Hannibal West	8.0 Very good 1,004 reviews	View
Garden House Bed and Breakfast	8.4 Very good 53 reviews	View

Top Murphy Island Hotel Reviews

Best Western On The River

8/10 Good

"The hotel was very nice and clean. Our only complaint was the outside noise. There were a lot of loud cars and motorcycles, probably there for a car show? We could also hear scraping of chairs from the breakfast room"

Motel 6 Hannibal, MO

10/10 Excellent

"This was our third time staying at this hotel. The staff is super friendly and helpful. Rooms are clean and well maintained. The pool is closed so that's a bummer, but it's location is easy to get in and out of and it's close to the action. We will be staying there again next year."

AmericInn by Wyndham Quincy

8/10 Good

"Comfortable beds and convenient location."

Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

8/10 Good

"Good stay. All was as expected."

Days Inn by Wyndham Hannibal

8/10 Good

"Upon arrival I was disappointed with the looks on the outside, so beware. Not the flashiest entrance. The manager didn’t seem to really care. Nice room, and the breakfast was awesome! Overall, for what we paid it was okay, but there is a really nice looking comfort in right next to the dollar general!"

Heritage Hotel Quincy

10/10 Excellent

"It was clean, quiet, great parking, the only thing that was less than great, was the breakfast, but we didn’t book it for that anyway."

Stoney Creek Inn Quincy

8/10 Good

"It was clean, nice staff, and reasonably priced."

Lighthouse Inn & Suites

10/10 Excellent

"Last minute getaway to Hannibal. Wonderful room, it was small, but decorated very cool. Cleanest room, and hot tub I’ve ever seen. It’s a block off the main downtown area. Small, clean pool. Staff was Great!"

Other attractions near Murphy Island

Mark Twain Memorial Lighthouse

8.8/10 (143 reviews)

You can find out about the history of Hannibal with a trip to Mark Twain Memorial Lighthouse. While in this family-friendly area, you can savour the top-notch restaurants.

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Riverview Park

You can find out about the history of Hannibal when you stop by Riverview Park. While in this family-friendly area, you can savour the top-notch restaurants.

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Bay Island

Commune with nature and explore the great outdoors at Bay Island during your travels in Palmyra. Take in the museums while you're in the area.

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Indian Mounds Park

After visiting Indian Mounds Park, make a plan to see the other sights and activities in Hannibal. While in this family-friendly area, you can savour the top-notch restaurants.

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Veteran's Sports Park

Veteran's Sports Park is just one of the places to see in Hannibal, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savour the top-notch restaurants.

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Molly Brown Museum and Home

8.4/10 (64 reviews)

You can browse the exhibits at Molly Brown Museum and Home, a museum with a story of its own, during your holiday in Hannibal. While in this walkable area, you can savour the top-notch restaurants.

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Jim's Journey: The Huck Finn Freedom Center

8.4/10 (33 reviews)

You can browse the exhibits at Jim's Journey: The Huck Finn Freedom Center, a museum with a story of its own, during your holiday in Hannibal. While in this family-friendly area, you can savour the top-notch restaurants.

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Mark Twain Boyhood Home and Museum

9.0/10 (278 reviews)

Find out about the history of Hannibal with a stop at Mark Twain Boyhood Home and Museum. While in this family-friendly area, you can savour the top-notch restaurants.

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Frequently asked questions

What's the area like around Murphy Island?

Murphy Island is located in Palmyra. You'll find 54 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay close to Murphy Island?

Quality Inn & Suites Hannibal West is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located 3.7 mi (6 km) from Murphy Island. Other good choices within a few miles include Best Western On The River and Motel 6 Hannibal, MO.

How many hotels will I be able to find near Murphy Island?

Expedia has 54 hotels and other accommodation options a few miles from Murphy Island.

If I need to cancel the hotel reservation for my stay near Murphy Island, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view the best deals available near Murphy Island.

What can I see and do near Murphy Island?

Jim's Journey: The Huck Finn Freedom Center, Mark Twain Boyhood Home and Museum and Molly Brown Museum and Home feature captivating exhibits. Mark Twain Memorial Lighthouse, Rockcliffe Mansion and Planters Barn Theater are landmarks that you won't want to miss. You might spend a leisurely day outdoors at Sodalis Nature Preserve and Sawyer's Creek Fun Park.

Search Hotels Near Murphy Island, Palmyra

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Our top choices for Murphy Island hotels

1. Sleep Inn & Suites Hannibal West

2. Best Western On The River

3. Riverside Inn Hannibal

4. Quality Inn & Suites Hannibal West

5. Garden House Bed and Breakfast

6. Lighthouse Inn & Suites

7. Comfort Inn & Suites - Hannibal

8. Motel 6 Hannibal, MO

9. Super 8 by Wyndham Hannibal

10. Days Inn by Wyndham Hannibal

11. Howard Johnson BY Wyndham Hannibal

12. Baymont by Wyndham Hannibal

13. Deck + River View: Loft in Downtown Hannibal

Compare popular hotels close to Murphy Island

Top Murphy Island Hotel Reviews

Best Western On The River

Motel 6 Hannibal, MO

AmericInn by Wyndham Quincy

Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

Days Inn by Wyndham Hannibal

Heritage Hotel Quincy

Stoney Creek Inn Quincy

Lighthouse Inn & Suites

Other attractions near Murphy Island

Mark Twain Memorial Lighthouse

Riverview Park

Bay Island

Indian Mounds Park

Veteran's Sports Park

Molly Brown Museum and Home

Jim's Journey: The Huck Finn Freedom Center

Mark Twain Boyhood Home and Museum

Frequently asked questions