The Best Hotels Closest to Mark Twain Boyhood Home and Museum in Hannibal - 2026 Updated Prices

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Our top choices for Mark Twain Boyhood Home and Museum hotels

A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.

A historic building with a stone facade and multiple windows, featuring a sign about Tom Sawyer's fence.

A wooden table with a bottle of champagne, two glasses, and scattered rose petals.

A hotel room with a bed, two bedside lamps, a headboard, and a patterned carpet.

1. Riverside Inn Hannibal

0.2 km from Mark Twain Boyhood Home and Museum

Janee

฿5,037

฿6,971 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

A spacious bathroom with a large bathtub, a walk-in shower, and a vanity with a mirror.

A swimming pool with lounge chairs and a covered seating area.

A modern living room with a grey sofa, a white armchair, a coffee table, and a patterned rug. There is a kitchen in the background with white cabinets and a black door.

2. Lighthouse Inn & Suites

0.6 km from Mark Twain Boyhood Home and Museum

Connie

฿5,342

฿7,322 total

includes taxes & fees

12 Oct - 13 Oct

A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.

A multi-level indoor pool area with a visible water slide, a towel rack, and a notice board.

A hotel kitchen with a buffet setup, including a coffee station and various food items.

3. Best Western On The River

< 0.1 km from Mark Twain Boyhood Home and Museum

Wei

฿3,688

฿4,254 total

includes taxes & fees

13 Oct - 14 Oct

A wooden staircase with a handrail, a small table with a lamp, and a chair in a room with a door and windows.

A dining area with a table set for four, surrounded by wooden chairs. A chandelier hangs above the table, and a lamp provides additional lighting.

A cozy living room with a fireplace, a red armchair, a globe, and various framed pictures on the mantel.

A large, two-story house with a porch and a sign indicating 'ONE WAY'.

4. Garden House Bed and Breakfast

0.3 km from Mark Twain Boyhood Home and Museum

Debbie

฿3,575

฿4,124 total

includes taxes & fees

22 Oct - 23 Oct

A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.

A spacious lobby with a fireplace, leather sofas, a coffee table, and a large window with blinds.

A building with a covered entrance and a sign indicating a clearance height of 13 feet.

A hotel room with two beds, a window with red curtains, an air conditioning unit, and two bedside lamps.

5. Motel 6 Hannibal, MO

2.9 km from Mark Twain Boyhood Home and Museum

Donna B

฿1,944

฿2,243 total

includes taxes & fees

14 Oct - 15 Oct

A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.

A hotel room with a large bed, a desk with a chair, a window with curtains, and a wall-mounted artwork.

A long hallway with a patterned carpet, wooden paneling on the walls, and a ceiling light.

A modern dining area with round tables and chairs, a flat-screen TV mounted on the wall, and a brick accent wall.

6. Super 8 by Wyndham Hannibal

3 km from Mark Twain Boyhood Home and Museum

Betty

฿2,070

฿2,388 total

includes taxes & fees

21 Oct - 22 Oct

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.

A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.

A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.

7. Sleep Inn & Suites Hannibal West

6.6 km from Mark Twain Boyhood Home and Museum

Patricia

฿3,962

฿4,609 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.

A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.

A hotel entrance with a central fountain, large columns, and a clear sky.

A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

8. Quality Inn & Suites Hannibal West

6.4 km from Mark Twain Boyhood Home and Museum

Gayle

฿2,534

฿2,948 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, a sofa, a desk, and a lamp.

A restaurant with multiple tables and chairs, an exit sign, and a counter area.

A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.

A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.

9. Comfort Inn & Suites - Hannibal

4.7 km from Mark Twain Boyhood Home and Museum

Jerry

฿2,599

฿3,099 total

includes taxes & fees

1 Nov - 2 Nov

A reception area with a marble counter, a 'Days Inn' sign, and a welcome mat.

A laundry room with a washing machine, dryer, and a shelf with detergent bottles.

A hotel room with a dining area, kitchenette, and a door leading to a hallway.

A hotel with a covered entrance, a parking lot, and a clear sky.

10. Days Inn by Wyndham Hannibal

4.9 km from Mark Twain Boyhood Home and Museum

Christian

฿2,081

฿2,400 total

includes taxes & fees

18 Oct - 19 Oct

A large indoor swimming pool with multiple levels of balconies, surrounded by seating areas and potted plants.

A clean, modern reception area with a reception desk, a clock, and a potted plant.

A kitchen with wooden cabinets, a granite countertop, and various food items and kitchen appliances.

A modern building with a red awning, a parking lot, and a sign indicating an entrance.

11. Howard Johnson BY Wyndham Hannibal

5 km from Mark Twain Boyhood Home and Museum

Debbie

฿1,962

฿2,278 total

includes taxes & fees

21 Oct - 22 Oct

An indoor swimming pool with a tiled ceiling, multiple levels with windows, and seating areas around the pool.

A kitchen with a granite countertop, wooden cabinets, and a herringbone-patterned floor.

A gym with cardio equipment, mirrored walls, and a view of a Pepsi store outside.

12. Baymont by Wyndham Hannibal

5 km from Mark Twain Boyhood Home and Museum

brian

฿1,853

฿2,151 total

includes taxes & fees

14 Oct - 15 Oct

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Compare popular hotels close to Mark Twain Boyhood Home and Museum

Property	Property class	Guest rating
Riverside Inn Hannibal	9.6 Exceptional 201 reviews	View
Lighthouse Inn & Suites	8.8 Excellent 47 reviews	View
Best Western On The River	8.6 Excellent 1,007 reviews	View
Garden House Bed and Breakfast	8.4 Very good 55 reviews	View
Motel 6 Hannibal, MO	7.4 Good 1,003 reviews	View

Top Mark Twain Boyhood Home and Museum Hotel Reviews

Best Western On The River

8/10 Good

"The hotel was very convenient for visiting the sites in Hannibal. The staff were friendly and the property was good for a one night stay."

Stoney Creek Inn Quincy

8/10 Good

"The hotel staff were friendly and check in was easy. The room was clean and there were plenty of towels and even a small Keurig coffee maker with pods. There is an Applebees right across the parking lot that was great. The beds were on the softer side, but still comfortable. The only negative was the noise from late night guests and early morning truck traffic and beeping from the business next door."

Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

10/10 Excellent

"Nice place. Convenient location."

Garden House Bed and Breakfast

8/10 Good

"Beautiful Queen Ann B&B, was reasonably priced and within walking distance to the river and down town Hannibal attractions."

Days Inn by Wyndham Hannibal

10/10 Excellent

"Everything was 5 star rating except the coffee from the automatic coffee dispenser."

Holiday Inn Quincy East by IHG

10/10 Excellent

"The hotel was in a great location with clean rooms."

Riverside Inn Hannibal

10/10 Excellent

"Beautiful view of the river! Easy access to downtown and shops/restaurants. The jacuzzi was wonderful and a nice bonus! We’ll definitely stay there again if we’re back in the area."

Comfort Inn & Suites - Hannibal

10/10 Excellent

"Rooms were clean. Staff was friendly."

Other attractions near Mark Twain Boyhood Home and Museum

Mark Twain Memorial Lighthouse

8.8/10 (143 reviews)

You can find out about the history of Hannibal with a trip to Mark Twain Memorial Lighthouse. While in this family-friendly area, you can savour the top-notch restaurants.

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Planters Barn Theater

8.8/10 (22 reviews)

Get tickets for a show at Planters Barn Theater, a popular theatre in Hannibal. While in this walkable area, you can savour the top-notch restaurants.

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Jim's Journey: The Huck Finn Freedom Center

8.4/10 (33 reviews)

You can browse the exhibits at Jim's Journey: The Huck Finn Freedom Center, a museum with a story of its own, during your holiday in Hannibal. While in this family-friendly area, you can savour the top-notch restaurants.

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Bluff City Theater

7.6/10 (5 reviews)

Get tickets for a show at Bluff City Theater, a theatre with a story to tell in Hannibal. While in this family-friendly area, you can savour the top-notch restaurants.

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Molly Brown Museum and Home

8.4/10 (64 reviews)

You can browse the exhibits at Molly Brown Museum and Home, a museum with a story of its own, during your holiday in Hannibal. While in this walkable area, you can savour the top-notch restaurants.

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Lovers Leap

8.8/10 (171 reviews)

Find out about the history of Hannibal when you spend time at Lovers Leap. While in this walkable area, you can savour the top-notch restaurants.

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Riverview Park

You can find out about the history of Hannibal when you stop by Riverview Park. While in this family-friendly area, you can savour the top-notch restaurants.

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Sodalis Nature Preserve

Explore the great outdoors at Sodalis Nature Preserve, a lovely green space in Hannibal. While in this family-friendly area, you can savour the top-notch restaurants.

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Frequently asked questions

What's the area like around Mark Twain Boyhood Home and Museum?

Mark Twain Boyhood Home and Museum is located in a welcoming area of Hannibal known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 40 hotels and other accommodation options you'll find within a mile.

What's the best place to stay close to Mark Twain Boyhood Home and Museum?

Adjacent to Mark Twain Boyhood Home and Museum, Best Western On The River is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. Other good choices close by include Lighthouse Inn & Suites and Garden House Bed and Breakfast.

How many hotels will I find near Mark Twain Boyhood Home and Museum?

Expedia has 40 hotels and other accommodation options within a mile from Mark Twain Boyhood Home and Museum.

If I need to cancel the hotel reservation for my stay near Mark Twain Boyhood Home and Museum, will I receive a refund?

Yes, most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the top deals on offer near Mark Twain Boyhood Home and Museum.

What can I see and do near Mark Twain Boyhood Home and Museum?

You'll want to browse the exhibits at Jim's Journey: The Huck Finn Freedom Center and Molly Brown Museum and Home. Mark Twain Memorial Lighthouse, Rockcliffe Mansion and Mark Twain Cave are notable landmarks to explore if you're in the area. You can enjoy live performances at Bluff City Theater and Planters Barn Theater.

Search Hotels Near Mark Twain Boyhood Home and Museum, Hannibal

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Treat yourself

Be picky

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Our top choices for Mark Twain Boyhood Home and Museum hotels

1. Riverside Inn Hannibal

2. Lighthouse Inn & Suites

3. Best Western On The River

4. Garden House Bed and Breakfast

5. Motel 6 Hannibal, MO

6. Super 8 by Wyndham Hannibal

7. Sleep Inn & Suites Hannibal West

8. Quality Inn & Suites Hannibal West

9. Comfort Inn & Suites - Hannibal

10. Days Inn by Wyndham Hannibal

11. Howard Johnson BY Wyndham Hannibal

12. Baymont by Wyndham Hannibal

Compare popular hotels close to Mark Twain Boyhood Home and Museum

Top Mark Twain Boyhood Home and Museum Hotel Reviews

Best Western On The River

Stoney Creek Inn Quincy

Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

Garden House Bed and Breakfast

Days Inn by Wyndham Hannibal

Holiday Inn Quincy East by IHG

Riverside Inn Hannibal

Comfort Inn & Suites - Hannibal

Other attractions near Mark Twain Boyhood Home and Museum

Mark Twain Memorial Lighthouse

Planters Barn Theater

Jim's Journey: The Huck Finn Freedom Center

Bluff City Theater

Molly Brown Museum and Home

Lovers Leap

Riverview Park

Sodalis Nature Preserve

Frequently asked questions