Find hotels in Murphy, MO from ฿2,247

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30 Dec - 31 Dec
Tomorrow
31 Dec - 1 Jan
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2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

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Our top choices for Murphy hotels

Lobby
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
St. Ann
9.4 out of 10, Exceptional, (2769)
"Very clean and will definitely stay there again next time!"
United States
Tonya
The price is ฿2,793
฿3,288 total
includes taxes & fees
6 Jan - 7 Jan 2026
Pear Tree Inn St. Louis Airport
Ballroom
The Wildwood Hotel

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1620)
"Very nice hotel"
United States
sharon
The Wildwood Hotel
Exterior
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very good, (1011)
"very friendly staff and good location "
United States
Heather
The price is ฿2,774
฿3,188 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn St. Charles St. Peters
Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1178)
"Great staff and location"
United States
Robin or David
The price is ฿3,070
฿3,651 total
includes taxes & fees
25 Jan - 26 Jan 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Lobby
Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1000)
"Very good place to stay"
United States
Jasur
The price is ฿2,458
฿2,899 total
includes taxes & fees
11 Jan - 12 Jan 2026
Sleep Inn & Suites O'Fallon MO - Technology Drive
Room, 2 Queen Beds, Accessible, Non Smoking (Mobility, Tub W/Grab Bars) | Desk, laptop workspace, iron/ironing board, free cots/infant beds
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
2.5 star property
St. Ann
9.2 out of 10, Wonderful, (1506)
"Good transport to and from car rental, a plus "
United States
Ralph
The price is ฿3,350
฿3,945 total
includes taxes & fees
7 Jan - 8 Jan 2026
Wingate by Wyndham St. Louis Airport
Lobby sitting area
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
8.0 out of 10, Very good, (1059)
"While the water constantly ran in the bathtub, the staff was amazing, the beds were comfy enough, the free breakfast was filling and checkout was easy. "
United States
jessica
The price is ฿2,638
฿3,047 total
includes taxes & fees
11 Jan - 12 Jan 2026
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Lobby
Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown
3.0 star property
Downtown West
8.0 out of 10, Very good, (623)
"Great stay "
United States
Kevin
The price is ฿2,446
฿2,860 total
includes taxes & fees
28 Jan - 29 Jan 2026
Home2 Suites by Hilton St. Louis Downtown
Exterior
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
Clayton
8.8 out of 10, Excellent, (3051)
"Clean room, good breakfast and good location "
United States
Martin
The price is ฿2,924
฿3,413 total
includes taxes & fees
30 Jan - 31 Jan 2026
Clayton Plaza Hotel & Extended Stay
Property amenity
Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown
2.5 star property
Downtown West
9.2 out of 10, Wonderful, (1004)
"Room was great! Staff were nice"
United States
Delaney
The price is ฿3,393
฿4,049 total
includes taxes & fees
28 Jan - 29 Jan 2026
Fairfield Inn & Suites by Marriott St. Louis Downtown
Property amenity
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station
3.0 star property
Downtown West
9.0 out of 10, Wonderful, (1775)
"Great stay! Great staff!!"
United States
Mike
The price is ฿2,917
฿3,411 total
includes taxes & fees
11 Jan - 12 Jan 2026
Pear Tree Inn St. Louis Near Union Station
Terrace/patio
Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
Richmond Heights
9.4 out of 10, Exceptional, (842)
"Clean, would stay again."
United States
Eryka
The price is ฿3,201
฿3,928 total
includes taxes & fees
1 Jan - 2 Jan 2026
Courtyard by Marriott St. Louis Brentwood
Pillow-top beds, in-room safe, desk, laptop workspace
Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
Woodson Terrace
9.2 out of 10, Wonderful, (1002)
"this is the perfect place to stay the night before going to the airport "
United States
Laurie
The price is ฿3,603
฿4,300 total
includes taxes & fees
7 Jan - 8 Jan 2026
Hyatt Select St. Louis Airport
Lobby
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
3.0 star property
Festus
8.0 out of 10, Very good, (897)
"Breakfast was great! Location right off interstate was perfect. The property is a little old."
United States
Mindy
The price is ฿2,928
฿3,348 total
includes taxes & fees
18 Jan - 19 Jan 2026
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Terrace/patio
Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia
2.5 star property
Columbia
8.6 out of 10, Excellent, (476)
"Breakfast was great and a very good atten"
United States
John
The price is ฿3,072
฿3,409 total
includes taxes & fees
12 Jan - 13 Jan 2026
Hampton Inn St. Louis - Columbia
Courtyard
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
Maryland Heights
7.4 out of 10, Good, (1000)
"Spacious suite, friendly staff. Check in was easy and everything looked clean"
United States
Jonathan
The price is ฿2,212
฿2,566 total
includes taxes & fees
11 Jan - 12 Jan 2026
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Lobby sitting area
Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South
2.5 star property
Festus
7.8 out of 10, Good, (914)
"Clean room. Easy check in"
United States
Henrick
The price is ฿2,394
฿2,798 total
includes taxes & fees
1 Jan - 2 Jan 2026
Comfort Inn Festus - St Louis South
Room, 2 Queen Beds | Hypo-allergenic bedding, free WiFi, bed sheets
Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown
2.5 star property
Downtown West
7.6 out of 10, Good, (601)
"Breakfast was delicious and room was comfy "
United States
Ronnesha
The price is ฿2,569
฿3,004 total
includes taxes & fees
18 Jan - 19 Jan 2026
Tru By Hilton St. Louis Downtown
Lobby
Best Western St. Louis-Kirkwood Route 66

Best Western St. Louis-Kirkwood Route 66

Best Western St. Louis-Kirkwood Route 66
3.5 star property
Kirkwood
8.4 out of 10, Very good, (1377)
"Our stay was quiet and comfortable. Only a well used slightly stained bathtub kept this review from being excellent. "
United States
Lucinda
The price is ฿2,919
฿3,414 total
includes taxes & fees
6 Jan - 7 Jan 2026
Best Western St. Louis-Kirkwood Route 66
Daily cooked-to-order breakfast for a fee
River City Casino & Hotel

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1455)
"Everything was absolutely wonderfull"
United States
Suada
The price is ฿3,072
฿4,027 total
includes taxes & fees
7 Jan - 8 Jan 2026
River City Casino & Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Murphy Hotel Reviews

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

10/10 Excellent
"Beautiful hotel. Many places to eat and things to do. Felt safe. "
Amy 1-night trip
Posted 2 days ago
St. Louis Union Station Hotel, Curio Collection by Hilton
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent
"Room was great, fancy tiles in bathroom area, breakfast was solid, hot tub good, pool is half indoors half outdoors with a barrier but nothing separating water in December so was great for cold plunging after hot tub, not so much for normal swimming. Exercise room has some cardio and lighter weights. "
Curtis 1-night trip
Posted 10 days ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

More cheap stays in Murphy

Relax Inn Saint Charles

Relax Inn Saint Charles

3800 Harry S Truman Blvd St. Charles MO
The price is ฿1,955 per night from 1 Jan to 2 Jan
฿1,955
฿2,247 total
1 Jan - 2 Jan 2026
includes taxes & fees
6.4/10 (1,004 reviews)

Frequently asked questions

Where is the best place to stay in Murphy?
Located 20 mi (32.1 km) from the heart of Murphy, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Hilton St. Louis Airport and Clayton Plaza Hotel & Extended Stay. See all available top hotels, or vacation rentals in Murphy.
If I need to cancel my hotel reservation in Murphy, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Murphy.
What is staying in Murphy like?
Travellers to Murphy will find plenty to explore and enjoy. There are 1737 hotels and other accommodation options in the surrounding area. Find out more about Murphy.
What is there to see in Murphy?
A favourite place to visit is Lone Elk Park. You'll also find Castlewood State Park and Route 66 State Park in the area. Take a look at what more there is to see and do in Expedia's Murphy guide.
What's the seasonal weather in Murphy?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Murphy is 1329 mm.

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