Mission Valley Packages (Flight + Hotel)

Book a Hotel + Flight or Car together to unlock savings

Where to stay in Mission Valley

Find the best Mission Valley areas and neighborhoods for the activities you enjoy most. Learn more about Mission Valley

Top hotels in Mission Valley

Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Fully refundableReserve now, pay when you stay
8/10 Very Good! (1,918 reviews)
"I think it was a good experience. Rooms were decent, the service is excellent. I will be coming back!"

Reviewed on 8 Aug 2025

Handlery Hotel
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 out of 5
2151 Hotel Circle South, San Diego, CA
Fully refundableReserve now, pay when you stay
8.6/10 Excellent! (1,155 reviews)
"Overall the hotel it’s nice. Just the room it’s small"

Reviewed on 6 Aug 2025

Hampton Inn San Diego/Mission Valley
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S, San Diego, CA
8.4/10 Very Good! (1,475 reviews)
"When asked if they had handicap parking, staff assumed I needed a wheelchair access room with an open shower even though my wife and I walked in. Shower made a mess on the floor."

Reviewed on 9 Aug 2025

Sheraton Mission Valley San Diego Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mission Valley holiday package cost?
From as low as . Yes, you read that correctly. Our Mission Valley holiday packages are the best way to make your budget last longer. Bundle your preferred flights, hotels and rental car and explore this top destination.
How do I get a cheap travel package to Mission Valley?
Booking a hotel and flight together with Expedia won't just save precious time — it'll save you cash too. A Mission Valley holiday package makes it simple to arrange the ideal trip. With more than 550 airlines across the world to pick from, finding flights that suit your busy schedule won't be a hassle. Not only that, we have over 1,000,000 properties globally to take your pick of. Now that's what you call choice. No matter who you are, Expedia puts the world within your reach.
Where should I stay in Mission Valley?
Most people who travel to Mission Valley put both San Diego Zoo and Balboa Park on their must-see lists. Why not book a hotel close to one of these fantastic attractions?
What are the top hotels in Mission Valley?
Lock in a room at Secluded, Charming And Unique Spacious Apartment Excellent Central Location. It's one of this area's most in-demand hotels. Another highly rated option in Mission Valley is Extended Stay America Suites San Diego Fashion Valley.
How far in advance should I book my Mission Valley holiday?
Savvy travellers book early. Air carriers usually release flights up to a year prior to departure, and this is a perfect opportunity to land some of the cheapest prices. Just been told you need to take all your holiday days next month? Don't fret. Expedia are never short on fantastic bargains to send you off on the getaway of your dreams, at an affordable price.
What does an Expedia Mission Valley travel package include?
Travel packages include hotels, rental cars and flights, but you can combine any of them to create your dream Mission Valley getaway. You can also add on fun things like activities and tours once you've made your booking. You're in control! When you bundle your bookings with Expedia, you'll score deals you won't find elsewhere.
What should I know before booking a Mission Valley travel package?
When you book your hotels, flights and car rentals together, you'll walk away with awesome discounts. Whether you're organising a mountain getaway in a cabin or prefer to stay in a ritzy city hotel, Expedia will help make it happen.
Can I choose my airline with a Mission Valley Expedia holiday package?
Yes, of course. We have more than 550 airline partners around the world, so opt for the carrier that best suits your budget and travel needs.
If I'm not able to travel, can I cancel my Mission Valley holiday package?
If your travel plans in Mission Valley have changed, it's a relief to know that you can cancel or amend your booking. If you booked less than 24 hours ago, you may be eligible for a refund. If your booking is older than that, your hotel, airline or car rental company may charge a cancellation fee. For more details, visit our Customer Service Portal.

Popular places to visit

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.