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Check prices for these dates

Tonight
23 Apr - 24 Apr
Tomorrow
24 Apr - 25 Apr
This weekend
24 Apr - 26 Apr
Next weekend
1 May - 3 May

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Our top choices for Mill Creek hotels

Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,003 reviews)
"Hotel is in a convenient central area. Was clean and staff was friendly."
United States
Michael
The price is ฿3,388
฿3,822 total
includes taxes & fees
17 May - 18 May
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,001 reviews)
"Hotel was nice and staff was quite helpful!"
United States
Linda
The price is ฿3,248
฿3,665 total
includes taxes & fees
10 May - 11 May
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (730 reviews)
"It was good, but a noticeable hole in the wall above the toilet paper."
United States
Martin
The price is ฿2,047
฿2,309 total
includes taxes & fees
30 Apr - 1 May
Quality Inn Cape Girardeau North
Indoor pool, outdoor pool

Hotel 7 Inn Anna

Hotel 7 Inn Anna
2.5 star property
Anna
6.6 out of 10, (221 reviews)
"Pool was broken unfortunately. The hotel is a little older and could use some updates but honestly the place was absolutely spotless! It smelled clean and fresh . Our bed was comfortable. The shower had great pressure and I could have stayed in there for hours lol . "
United States
Stephanie
The price is ฿2,643
฿3,066 total
includes taxes & fees
26 Apr - 27 Apr
Hotel 7 Inn Anna
Desk, laptop workspace, blackout curtains, free cots/infant beds

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,003 reviews)
"Would stay again when in the area."
United States
Jack
The price is ฿2,339
฿2,639 total
includes taxes & fees
25 May - 26 May
Pear Tree Inn Cape Girardeau West
Lobby sitting area

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (553 reviews)
"Really nice and clean rooms. Staff was super friendly and let me check in 2 hours early because my neck had been bothering me and i needed to lay down"
United States
Raun
The price is ฿4,269
฿4,816 total
includes taxes & fees
3 May - 4 May
The Riverview
Lobby

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (806 reviews)
"We enjoyed our stay"
United States
Wanda
The price is ฿3,548
฿4,003 total
includes taxes & fees
6 May - 7 May
Hampton Inn Cape Girardeau I 55 East
Lobby

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (176 reviews)
"Nice room, good breakfast "
United States
KENNETH
The price is ฿3,166
฿3,571 total
includes taxes & fees
6 May - 7 May
Fairfield Inn & Suites by Marriott Cape Girardeau
Free daily buffet breakfast

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
"Clean room, friendly staff, great breakfast. "
United States
jessica
The price is ฿3,021
฿3,408 total
includes taxes & fees
25 May - 26 May
Drury Inn & Suites Cape Girardeau
Desk, free WiFi

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.2 out of 10, (220 reviews)
"Easy to check in quite nice lil place "
United States
Damian
The price is ฿2,420
฿2,827 total
includes taxes & fees
25 Apr - 26 Apr
Town House Inn Cape Giradreau
Front of property – evening/night

Makanda Inn

Makanda Inn
3.5 star property
Makanda
10.0 out of 10, Exceptional, (36 reviews)
"This is such a warm and inviting place to stay! The caretaker was very kind and available for any questions or needs, and made a great breakfast! It is clean and well-stocked with anything you might need. Will definitely be back! "
United States
Roxanne
The price is ฿8,452
฿9,636 total
includes taxes & fees
27 Apr - 28 Apr
Makanda Inn
Lobby

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (503 reviews)
"Great place! "
United States
Michelle
The price is ฿4,485
฿5,083 total
includes taxes & fees
26 Apr - 27 Apr
Courtyard by Marriott Cape Girardeau Downtown
Lobby

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (20 reviews)
"We love staying at this inn. It truly feels like we’re in a friend’s beautifully appointed home. We’ll be back here again for certain. "
United States
Elsa
The price is ฿4,849
฿5,471 total
includes taxes & fees
5 May - 6 May
Rockwood Inn
Exterior

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.0 out of 10, Very good, (923 reviews)
"Great place"
United States
Chris
The price is ฿2,826
฿3,367 total
includes taxes & fees
18 May - 19 May
Candlewood Suites Cape Girardeau by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mill Creek Hotel Reviews

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

8/10 Good
"The room that we got the window shades were broken. "
Diane 1-night trip
Posted 1 hour ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

More cheap stays in Mill Creek

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO
The price is ฿2,047 per night from 30 Apr to 1 May
฿2,047
฿2,309 total
30 Apr - 1 May
includes taxes & fees
7.2/10 Good! (730 reviews)

Frequently asked questions

Where is the best place to stay in Mill Creek?
Drury Plaza Hotel Cape Girardeau Conference Center, located 18.1 mi (29.2 km) from the heart of Mill Creek, is a top choice for your stay, based on our traveller data. Other good options for your visit to the area are The Riverview and Pear Tree Inn Cape Girardeau West. See all available top hotels, or vacation rentals in Mill Creek.
If I need to cancel my hotel reservation in Mill Creek, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If your reservation is non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Mill Creek.
What's it like to stay in Mill Creek?
Those travelling to Mill Creek will definitely enjoy the sights to see and things to do. There are 161 hotels and other accommodation options in the surrounding area. Find out more about Mill Creek.
What should I do while I'm visiting Mill Creek?
Places to visit in the wider area include Trail of Tears State Park, Century Casino & Hotel Cape Girardeau and Hunter Valley Winery. You'll also find Show Me Center and Anna City Park in the area. Take a look at what more there is to see and do in Expedia's Mill Creek guide.
What's the weather like in Mill Creek?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 4°C. Average annual precipitation for Mill Creek is 1431 mm.