Default HTG hotel image

Find hotels in Mayo, SC from ฿1,864

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
22 Oct - 23 Oct
Tomorrow
23 Oct - 24 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Filter by

Star rating

Guest rating

Our top choices for Mayo hotels

A buffet with various food items, including omelets and cheese.
A conference room with a long table, blue chairs, framed artwork on the walls, and a sign for Holiday Inn Express.
A hotel room with two beds, a desk, and a view of the outdoors.
A vending area with Coca-Cola and Sprite refrigerated drinks, a 'happy place' sign, and snack baskets on shelves.

1. Holiday Inn Express Gaffney by IHG

Holiday Inn Express Gaffney by IHG
Gaffney
United States
VilmarisRuperto
฿2,554
฿2,784 total
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express Gaffney by IHG
A hotel lobby with a bar area, seating with patterned upholstery, and a central coffee table.
A hotel room with a large bed, a desk with a television, a chair, and a small table.
A snack and beverage vending area with various snacks and drinks.
A hotel reception desk with a 'Welcome to the Palmetto State' sign, a 'Manager On Duty' sign, and a 'Hilton Honors' sign.

2. Hampton Inn Gaffney

Hampton Inn Gaffney
Gaffney
United States
William H
฿3,313
฿3,611 total
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn Gaffney
A modern lobby with a blue sofa, a reception desk, and a large cityscape painting.
A Best Western Plus hotel with a parking lot and multiple cars parked in front.
A modern restaurant with a bar area, large windows, and a kitchen visible in the background.
A hotel room with two beds, a nightstand, and a wall-mounted TV.

3. Best Western Plus Spartanburg

Best Western Plus Spartanburg
Spartanburg
United States
Sasha
฿2,930
฿3,317 total
includes taxes & fees
1 Nov - 2 Nov
Best Western Plus Spartanburg
A modern living room with a fireplace, two sofas, and a coffee table.
A hotel lobby with multiple seating areas, a reception desk, and a fireplace.
A modern gym with various exercise equipment, motivational wall graphics, and a large window offering a view of the outdoors.
A hotel room with two beds, a desk, a TV, and a window with curtains.

4. Best Western Spartanburg Northwest

Best Western Spartanburg Northwest
Spartanburg
United States
Herbert
฿2,983
฿3,377 total
includes taxes & fees
22 Nov - 23 Nov
Best Western Spartanburg Northwest
Room
A wooden gazebo with a metal roof, a bench, and a ramp leading up to it.
A modern lobby with a large white reception desk, brown leather sofas, a round coffee table, and a ceiling light fixture.
A reception area with wooden reception desks, framed artwork, and a white door.

5. Days Inn by Wyndham Spartanburg

Days Inn by Wyndham Spartanburg
Boiling Springs
United States
Lyudmila
฿2,654
฿2,946 total
includes taxes & fees
26 Oct - 27 Oct
Days Inn by Wyndham Spartanburg
A hotel dining area with multiple tables and chairs, a television mounted on a wall, and a kitchen area visible in the background.
A living room with a sofa, two armchairs, a coffee table, and a patterned rug.
Property amenity
A Sleep Inn hotel with a covered entrance, a flagpole with the American flag, and a parking lot.

6. Sleep Inn Gaffney at I-85

Sleep Inn Gaffney at I-85
Gaffney
United States
Ken
฿1,751
฿1,961 total
includes taxes & fees
15 Nov - 16 Nov
Sleep Inn Gaffney at I-85
A hotel room with two beds, a desk, a refrigerator, a television, and a bathroom visible through an arched doorway.
A hotel kitchen with a buffet setup, including a coffee station, a refrigerator, and a microwave.
A modern bathroom with a large bathtub, a chair, and a floor lamp.
A hotel with a well-lit entrance, multiple parking spaces, and a clear view of the sky.

7. Comfort Inn & Suites Spartanburg North

Comfort Inn & Suites Spartanburg North
Spartanburg
United States
Lisa
฿2,828
฿3,139 total
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn & Suites Spartanburg North
A modern living room with a stone accent wall, a flat-screen TV, and a blue abstract rug.
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
A modern hotel with a prominent Fairfield sign, multiple floors, and a well-lit entrance.
A modern lobby with a sofa, armchairs, and a coffee table. There is a reception desk and a dining area in the background.

8. Fairfield by Marriott Inn & Suites Spartanburg Downtown

Fairfield by Marriott Inn & Suites Spartanburg Downtown
Spartanburg
United States
Zachary
฿4,827
฿5,358 total
includes taxes & fees
1 Nov - 2 Nov
Fairfield by Marriott Inn & Suites Spartanburg Downtown
A lobby with a leather sofa, two lamps, a painting, and potted plants.
A hotel lobby with a reception desk, a waiting area with a chair, and a large window providing a view of the outside.
A hotel room with two beds, a desk, a chair, a TV, and a bathroom visible through an open door.
A swimming pool with a brick border and a metal ladder, surrounded by a fence and a house in the background.

9. Quality Inn Gaffney I-85

Quality Inn Gaffney I-85
Gaffney
United States
Kathy
฿1,665
฿1,865 total
includes taxes & fees
22 Nov - 23 Nov
Quality Inn Gaffney I-85
A modern reception area with a counter, seating, and a bookshelf with various items.
A bar area with a long counter, bar stools, and a variety of bottles and glasses.
Bar (on property)
A clinical setting with medical equipment, a large mirror, and a window providing natural light.

10. Holiday Inn Spartanburg Northwest by IHG

Holiday Inn Spartanburg Northwest by IHG
Spartanburg
United States
Carla
฿3,307
฿3,671 total
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Spartanburg Northwest by IHG
A hotel room with a bed, a blue sofa, a wooden coffee table, a desk with a chair, and a framed abstract painting on the wall.
A food service counter with a sign that reads "EXPRESS START".
A large indoor swimming pool with a diving board, multiple doors, and seating areas.
A hotel room with a blue sofa, a wooden coffee table, a bed with white linens, a desk with a chair, and a large window.

11. Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Spartanburg
United States
Nephie
฿3,712
฿4,120 total
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
A conference room with a long table, blue and orange chairs, and a reception desk in the background.
A gym with treadmills, elliptical machines, and weight machines.
A coffee station with labeled dispensers for hot water, decaf roast, light roast, and dark roast coffee.
A Hampton Inn hotel with a clear entrance, well-maintained lawn, and a flagpole.

12. Hampton Inn Spartanburg-North I-85

Hampton Inn Spartanburg-North I-85
Spartanburg
United States
Britt
฿4,256
฿4,724 total
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn Spartanburg-North I-85
A hotel room with a bed, a TV, a desk, and a microwave.
Two vending machines, one with a Pepsi logo and the other with a FreshChoices label.
A multi-story building with a covered parking area.
A restaurant with red chairs and a counter with food items.

13. Red Roof Inn Gaffney

Red Roof Inn Gaffney
Gaffney
United States
Belinda
฿2,201
฿2,464 total
includes taxes & fees
25 Oct - 26 Oct
Red Roof Inn Gaffney
A lobby with a reception desk, a clock, and an exit sign.
A laundry room with multiple washing machines and dryers, wooden flooring, and informational posters on the walls.
A multi-story building with a parking lot in front.
A clean, modern office space with vending machines, a coffee machine, and a trash can.

14. USA Economy Lodge

USA Economy Lodge
Spartanburg
United States
Brandy
฿1,935
฿2,148 total
includes taxes & fees
26 Oct - 27 Oct
USA Economy Lodge
An outdoor seating area with sofas, a fire pit, and string lights.
A modern lounge area with seating arrangements, a large window offering a view of the outdoors, and contemporary lighting fixtures.
A modern hotel with a multi-story structure, large windows, and a prominent vertical light strip.
A modern interior with hanging chairs, tables, and a view of the parking lot.

15. Tru by Hilton Spartanburg

Tru by Hilton Spartanburg
Spartanburg
United States
Volodymyr
฿3,570
฿3,962 total
includes taxes & fees
23 Nov - 24 Nov
Tru by Hilton Spartanburg
A multi-level hotel lobby with seating areas, a fireplace, and a staircase.
A modern hotel building with a large glass facade, a covered entrance, and a sign reading "Four Points by Sheraton".
A spacious lobby with a high ceiling, modern furniture, and large windows offering views of the outdoors.
An indoor swimming pool with clear blue water, surrounded by lounge chairs and wooden panel walls.

16. Four Points by Sheraton Spartanburg

Four Points by Sheraton Spartanburg
Spartanburg
United States
Elaine
฿3,614
฿4,012 total
includes taxes & fees
1 Nov - 2 Nov
Four Points by Sheraton Spartanburg
A modern kitchen with a central island, equipped with a microwave, toaster, and coffee machine.
A hotel room with a desk, office chair, sofa, and a large wall art piece.
A modern lobby with blue sofas, a reception desk, and a glass coffee table.
A gym with treadmills, elliptical machines, and weight machines.

17. Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall
Spartanburg
United States
Willie
฿2,957
฿3,283 total
includes taxes & fees
22 Nov - 23 Nov
Comfort Suites At WestGate Mall
A hotel room with two beds, a desk, a chair, and a large window with autumn foliage artwork.
A hotel room with a wooden desk, a black chair, a small refrigerator, a microwave, and a TV on the wall.
A spacious indoor area with a large glass door leading outside, a ceiling fan, and a counter with various items.
A self-service coffee station with a Folgers Select Brew coffee maker and a vintage-themed beverage dispenser.

18. Days Inn by Wyndham Spartanburg Waccamaw

Days Inn by Wyndham Spartanburg Waccamaw
Spartanburg
United States
Rebecca
฿2,085
฿2,314 total
includes taxes & fees
25 Oct - 26 Oct
Days Inn by Wyndham Spartanburg Waccamaw
A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.
A reception area with a curved desk, a coffee station, and a seating area with a red sofa.
A restaurant with a view of the parking lot, featuring tables and chairs, a counter, and a door marked "EXIT".
A hotel room with a large bed, two bedside tables, a window with curtains, a chair, and a view of the outside.

19. Econo Lodge Gaffney

Econo Lodge Gaffney
Gaffney
United States
Md Khairul
฿1,665
฿1,864 total
includes taxes & fees
16 Nov - 17 Nov
Econo Lodge Gaffney
A hotel lobby with a curved outdoor seating area, a fire pit, and a pool.
A modern kitchen with marble countertops, wooden shelves, and a wine station.
A grand hotel lobby with a marble staircase, ornate carpet, and large landscape paintings on the walls.
A spacious lobby with a high ceiling, chandeliers, a registration desk, and potted plants.

20. Spartanburg Marriott

Spartanburg Marriott
Spartanburg
United States
Daniel
฿3,982
฿4,420 total
includes taxes & fees
1 Nov - 2 Nov
Spartanburg Marriott
View all properties

Hotels recommended for families in Mayo

A buffet with various food items, including omelets and cheese.
A conference room with a long table, blue chairs, framed artwork on the walls, and a sign for Holiday Inn Express.
A hotel room with two beds, a desk, and a view of the outdoors.
A vending area with Coca-Cola and Sprite refrigerated drinks, a 'happy place' sign, and snack baskets on shelves.

Holiday Inn Express Gaffney by IHG

Holiday Inn Express Gaffney by IHG
Gaffney
฿2,554
฿2,784 total
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express Gaffney by IHG
A hotel lobby with a bar area, seating with patterned upholstery, and a central coffee table.
A hotel room with a large bed, a desk with a television, a chair, and a small table.
A snack and beverage vending area with various snacks and drinks.
A hotel reception desk with a 'Welcome to the Palmetto State' sign, a 'Manager On Duty' sign, and a 'Hilton Honors' sign.

Hampton Inn Gaffney

Hampton Inn Gaffney
Gaffney
฿3,313
฿3,611 total
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn Gaffney
A modern lobby with a blue sofa, a reception desk, and a large cityscape painting.
A Best Western Plus hotel with a parking lot and multiple cars parked in front.
A modern restaurant with a bar area, large windows, and a kitchen visible in the background.
A hotel room with two beds, a nightstand, and a wall-mounted TV.

Best Western Plus Spartanburg

Best Western Plus Spartanburg
Spartanburg
฿2,930
฿3,317 total
includes taxes & fees
1 Nov - 2 Nov
Best Western Plus Spartanburg
A hotel dining area with multiple tables and chairs, a television mounted on a wall, and a kitchen area visible in the background.
A living room with a sofa, two armchairs, a coffee table, and a patterned rug.
Property amenity
A Sleep Inn hotel with a covered entrance, a flagpole with the American flag, and a parking lot.

Sleep Inn Gaffney at I-85

Sleep Inn Gaffney at I-85
Gaffney
฿1,751
฿1,961 total
includes taxes & fees
15 Nov - 16 Nov
Sleep Inn Gaffney at I-85
Room
A wooden gazebo with a metal roof, a bench, and a ramp leading up to it.
A modern lobby with a large white reception desk, brown leather sofas, a round coffee table, and a ceiling light fixture.
A reception area with wooden reception desks, framed artwork, and a white door.

Days Inn by Wyndham Spartanburg

Days Inn by Wyndham Spartanburg
Boiling Springs
฿2,654
฿2,946 total
includes taxes & fees
26 Oct - 27 Oct
Days Inn by Wyndham Spartanburg
A lobby with a leather sofa, two lamps, a painting, and potted plants.
A hotel lobby with a reception desk, a waiting area with a chair, and a large window providing a view of the outside.
A hotel room with two beds, a desk, a chair, a TV, and a bathroom visible through an open door.
A swimming pool with a brick border and a metal ladder, surrounded by a fence and a house in the background.

Quality Inn Gaffney I-85

Quality Inn Gaffney I-85
Gaffney
฿1,665
฿1,865 total
includes taxes & fees
22 Nov - 23 Nov
Quality Inn Gaffney I-85
A modern living room with a fireplace, two sofas, and a coffee table.
A hotel lobby with multiple seating areas, a reception desk, and a fireplace.
A modern gym with various exercise equipment, motivational wall graphics, and a large window offering a view of the outdoors.
A hotel room with two beds, a desk, a TV, and a window with curtains.

Best Western Spartanburg Northwest

Best Western Spartanburg Northwest
Spartanburg
฿2,983
฿3,377 total
includes taxes & fees
22 Nov - 23 Nov
Best Western Spartanburg Northwest
A lobby with a reception desk, a clock, and an exit sign.
A laundry room with multiple washing machines and dryers, wooden flooring, and informational posters on the walls.
A multi-story building with a parking lot in front.
A clean, modern office space with vending machines, a coffee machine, and a trash can.

USA Economy Lodge

USA Economy Lodge
Spartanburg
฿1,935
฿2,148 total
includes taxes & fees
26 Oct - 27 Oct
USA Economy Lodge
Save an average of 15% on thousands of hotels when you're signed in

Top Mayo Hotel Reviews

Motel 6 Spartanburg, Sc – Northwest / Business 85

Motel 6 Spartanburg, Sc – Northwest / Business 85

8/10 Good
"Clean quiet rooms. No amenities. Small refrigerator at the main desk for purchase of water, juice a d snacks"
Darryl 1-night trip
Posted 2 hours ago
Motel 6 Spartanburg, Sc – Northwest / Business 85
Best Western Spartanburg I-26

Best Western Spartanburg I-26

10/10 Excellent
"All good for the purpose of this trip ."
Julia 3-night trip
Posted 6 hours ago
Best Western Spartanburg I-26
Hilton Garden Inn Spartanburg

Hilton Garden Inn Spartanburg

8/10 Good
"The room was nice. I really appreciate the faucet placement in the shower. The information said there was a shuttle service. There was not."
Nancy 1-night trip
Posted 2 days ago
Hilton Garden Inn Spartanburg
Days Inn by Wyndham Spartanburg Waccamaw

Days Inn by Wyndham Spartanburg Waccamaw

10/10 Excellent
"Nice place very clean with a very helpful staff."
Lori 1-night trip
Posted 4 days ago
Days Inn by Wyndham Spartanburg Waccamaw
Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

10/10 Excellent
"The front desk staff was exceptionally pleasant. The hotel was clean and smelled amazing. Very comfortable and relaxing. Breakfast was good! Had a great stay and we will be back!"
aprelle 1-night trip
Posted 3 weeks ago
Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

More cheap stays in Mayo

Motel 6 Spartanburg, Sc – Northwest / Business 85

Motel 6 Spartanburg, Sc – Northwest / Business 85

820 Hospitality Drive Spartanburg SC
฿1,942
฿2,156 total
15 Nov - 16 Nov
includes taxes & fees
7.6/10 Good! (193 reviews)
Motel 6 Spartanburg, Sc – Northwest / Business 85
WoodSpring Suites Spartanburg - Duncan

WoodSpring Suites Spartanburg - Duncan

255 Frontage Rd. Duncan SC
฿2,150
฿2,419 total
24 Oct - 25 Oct
includes taxes & fees
WoodSpring Suites Spartanburg - Duncan
Holiday Inn Express Gaffney by IHG

Holiday Inn Express Gaffney by IHG

1031 HYATT STREET Gaffney SC
฿2,554
฿2,784 total
1 Nov - 2 Nov
includes taxes & fees
8.8/10 Excellent! (542 reviews)
Holiday Inn Express Gaffney by IHG
Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

458 West Blackstock Road Spartanburg SC
฿2,957
฿3,283 total
22 Nov - 23 Nov
includes taxes & fees
Comfort Suites At WestGate Mall
Best Western Spartanburg I-26

Best Western Spartanburg I-26

488 South Blackstock Road Spartanburg SC
฿3,113
฿3,456 total
15 Nov - 16 Nov
includes taxes & fees
9/10 Wonderful! (79 reviews)
Best Western Spartanburg I-26
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

161 Sha Lane Spartanburg SC
฿3,712
฿4,120 total
1 Nov - 2 Nov
includes taxes & fees
8.6/10 Excellent! (1,000 reviews)
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Frequently asked questions

Where is the best place to stay in Mayo?
Best Western Spartanburg I-26, located 13.4 mi (21.5 km) from the heart of Mayo, is a top choice for your stay, based on our traveller data. Other good options for your stay in the area are Comfort Suites At WestGate Mall and Spartanburg Marriott. See all available top hotels, or vacation rentals in Mayo.
If I need to cancel my hotel reservation in Mayo, will I receive a refund?
Yes, you'll find most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Mayo.
How is it to stay in Mayo?
Travellers to Mayo will find plenty to explore and enjoy. There are 500 hotels and other accommodation options in the surrounding area. Find out more about Mayo.
What should I see while I'm in Mayo?
Places to visit in the wider area include Lake Blalock Park, Gaffney Outlet Marketplace and G.B. Hodge Center. You'll also find Woodfin Ridge Golf Club and Asheville Highway Commons in the area. Take a look at what more there is to see and do in Expedia's Mayo guide.
What's the seasonal weather in Mayo?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Mayo is 1310 mm.

Explore a world of travel with Expedia