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Check prices for these dates

In two weeks
26 Jun - 28 Jun
In two months
7 Aug - 9 Aug
In three months
4 Sep - 6 Sep
In four months
2 Oct - 4 Oct

Our top choices for La Mesa holiday rentals

House (3 Bedrooms) | Interior

Mt. Nebo Oasis in La Mesa w/ Wraparound Deck

Mt. Nebo Oasis in La Mesa w/ Wraparound Deck
3.0 star property
Windsor Hills
The price is ฿10,036
฿24,078 total
includes taxes & fees
22 Jun - 23 Jun
Mt. Nebo Oasis in La Mesa w/ Wraparound Deck
Lobby sitting area

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (387 reviews)
"Great place to stay. Clean, friendly staff."
United States
Heber
The price is ฿3,766
฿4,246 total
includes taxes & fees
15 Jun - 16 Jun
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.8 out of 10, Exceptional, (162 reviews)
"Nice and very friendly staff was a great stay"
United States
Alexander
The price is ฿4,649
฿6,357 total
includes taxes & fees
15 Jun - 16 Jun
City24 Hotel Little Italy Mission Hills
Lobby

Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
Downtown San Diego
8.4 out of 10, Very good, (139 reviews)
"This little place was great and super convenient"
United States
Valerie
The price is ฿3,533
฿4,019 total
includes taxes & fees
16 Jun - 17 Jun
Little Italy Inn - Limited Service Apart Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

10/10 Excellent
"The Hard Rock Hotel SD is in the heart of the Gaslamp neighborhood, making it an ideal location for exploring the area. It’s very walkable, and the hotel itself has a Nobu restaurant, as well as several other restaurants and bars. I highly recommend it! They have fantastic pool parties on the roof and there’s something to do for everyone. We stayed in a suite and it was spacious and clean. The view of the city was beautiful."
Christopher Lamarr 3-night trip
Posted less than an hour ago
Hard Rock Hotel San Diego

Find out more about La Mesa

Search for holiday rentals in La Mesa on Expedia! You can easily find your home rentals, villas, holiday apartments in La Mesa using one of the methods below:

  • View our selection of featured holiday rentals in La Mesa
  • Use the map to find apartments and other holiday homes in the La Mesa neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in La Mesa while they last

Look no further and take a look at our great range of rental properties in La Mesa!

Frequently asked questions

Are there holiday rentals in La Mesa?

Yes, there are holiday rentals in La Mesa close to La Mesa Memorial Fine Arts Center, or you can select a more secluded option if you're looking for a relaxing stay. Visitors like the top-notch restaurants and shops in La Mesa. Leave some time to check out the zoo and entertainment venues during your trip.

How many holiday rentals are there in La Mesa?

With 73 Expedia holiday rentals, you're guaranteed to find just the right place for your La Mesa stay.

What can I see and do in La Mesa?

Explore the area and cultural attractions such as Computer Museum of America, or visit one of the family-friendly sights such as San Diego Zoo. While in the area, you can also visit popular places such as Petco Park and USS Midway Museum.

What are holiday rentals like in La Mesa?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in La Mesa. Holiday rentals feature amenities such as WiFi and washers and dryers so your stay will be comfortable. If you're concerned about a sanitised environment, holiday rentals can offer a sense of seclusion away from public hotel lifts and busy concierge desks while still allowing you the enjoyment of travel. You'll also have more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a great choice for a small group gathering.