Keowee Holiday Rentals, Seneca: Private House Rentals

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Our top choices for Keowee hotels

An outdoor patio area with a fire pit, seating, and string lights.

A food court with a beverage display, seating area, and a Clemson University sign.

A modern restaurant with a central counter, seating area, and a TV displaying news.

A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.

1. Tru by Hilton Seneca Clemson

Seneca

Curtis

฿3,516

฿3,868 total

includes taxes & fees

18 Oct - 19 Oct

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

A spacious dining area with a long wooden table and patterned upholstered chairs.

An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.

2. Lakeside Lodge Clemson

Seneca

Christopher

฿3,623

฿4,497 total

includes taxes & fees

30 Sept - 1 Oct

A golf course with a water body, trees, and a distant view of a bridge.

A golf course with a clubhouse, surrounded by dense trees and a large body of water.

A large, curved swimming pool with lounge chairs and umbrellas, surrounded by landscaped areas and a building in the background.

A modern building with a central entrance, surrounded by a well-maintained lawn and trees.

3. Clemson University's James F. Martin Inn

Clemson

Jennifer

฿3,714

฿4,123 total

includes taxes & fees

23 Sept - 24 Sept

A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.

A hotel room with a bed, a desk, a TV, a mirror, and a nightstand with a lamp.

A spacious indoor area with multiple levels of balconies, seating areas, and a central open space.

A spacious indoor area with multiple seating arrangements, a ping pong table, and a bar area with purple accents.

4. Best Western Plus Clemson Hotel & Conference Center

Clemson

David

฿3,370

฿3,741 total

includes taxes & fees

24 Sept - 25 Sept

A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

A modern bar area with a wooden ceiling, green bar stools, and a bar counter.

A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.

A spacious living area with a sofa, ottoman, and chairs, a dining area with a table, and a kitchen in the background.

5. The Shepherd Hotel Downtown Clemson

Clemson

Laurrie

฿7,944

฿8,818 total

includes taxes & fees

4 Oct - 5 Oct

A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.

A hotel with a brick facade, multiple windows, and a sign reading "The Inn at Patrick Square".

A brick building with a sign reading "The Inn at Patrick Square".

A hotel lobby with a long corridor, seating areas, and a reception desk.

6. The Inn at Patrick Square

Clemson

Christy

฿4,952

฿5,497 total

includes taxes & fees

28 Sept - 29 Sept

A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.

A bar area with a counter, multiple chairs, and a display of bottles and glasses.

A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.

7. The Abernathy of Clemson

Clemson

Robert

฿5,355

฿5,944 total

includes taxes & fees

7 Oct - 8 Oct

A modern kitchen area with a bar counter and seating.

A modern living room with a grey sofa, purple and orange cushions, a coffee table with magazines, and a large window with patterned curtains.

A Hampton Inn with a modern design, featuring a prominent entrance and outdoor seating area.

A vending area with snacks and beverages, including chips and soda.

8. Hampton Inn Clemson-University Area

Clemson

Blaise

฿3,516

฿3,903 total

includes taxes & fees

4 Oct - 5 Oct

A hotel hallway with a carpeted floor, light-colored walls, and doors on both sides.

A hotel room with a bed, a sofa, a small round table, a lamp, and artwork on the wall.

A swimming pool with lounge chairs and a no diving sign.

A Comfort Inn & Suites hotel with a modern design, featuring a prominent sign and a well-maintained outdoor area with landscaping.

9. Comfort Inn & Suites Clemson - University Area

Clemson

Jinna M

฿3,475

฿3,857 total

includes taxes & fees

18 Oct - 19 Oct

A modern office space with a desk, computer, and patterned chairs.

A hotel breakfast area with a self-serve station, including a refrigerator, coffee machine, and fruit display.

A hotel room with a large bed, a desk, a chair, a mirror, and a framed picture on the wall.

A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.

10. Holiday Inn Express & Suites Clemson by IHG

Clemson

John

฿4,288

฿4,759 total

includes taxes & fees

4 Oct - 5 Oct

A modern bar area with a menu board, bar stools, and a countertop with various items.

A Courtyard Marriott hotel with a brick facade, multiple floors, and a covered entrance area.

A modern lobby with a reception desk, a seating area with three chairs, a round table, and a bookshelf with books.

A modern dining area with a bar, bar stools, and a patterned rug.

11. Courtyard Marriott Clemson

Clemson

kim

฿4,756

฿5,280 total

includes taxes & fees

30 Sept - 1 Oct

A poolside area with outdoor seating and a view of a lake and forested hills.

A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

A modern lobby with a reception desk, seating area, and a vending machine.

12. Fairfield Inn & Suites Seneca Clemson Univ Area

Seneca

Angela

฿3,997

฿4,397 total

includes taxes & fees

27 Sept - 28 Sept

A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

A wall with a decorative design featuring a building, trees, and a sky with clouds.

A hotel room with two beds, a desk, a television, and a clock on the wall.

A tiger mascot holding a sign with "HOWARD'S ROCK" text, a staircase, and a desk with a computer.

13. Inn @ Clemson

Clemson

Terry

฿2,662

฿2,955 total

includes taxes & fees

23 Sept - 24 Sept

A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

A reception area with a brick wall, a reception desk, and a glass door leading outside.

A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

14. Best Western Seneca-Clemson

Seneca

Michelle

฿3,503

฿3,854 total

includes taxes & fees

28 Sept - 29 Sept

A restaurant interior with a counter, seating area, and a TV mounted on the wall.

A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

A hotel room with a bed, desk, TV, and a bathroom visible through an open door.

A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.

15. Quality Inn Seneca US-123

Seneca

Julie

฿2,597

฿3,059 total

includes taxes & fees

24 Sept - 25 Sept

A white, two-story house with a front porch, surrounded by trees and shrubs.

A bedroom with two beds, a TV, and a fireplace.

A two-story building with a white exterior, a front door, and a balcony.

A hallway with a wooden bench, a chair, a cabinet, and a painting on the wall.

16. Liberty Hall Bed and Breakfast

Pendleton

Christine

฿3,792

฿4,209 total

includes taxes & fees

20 Oct - 21 Oct

A hotel room with a large bed, a desk, a chair, a bathtub, and a large window.

A modern kitchen with a long counter, built-in appliances, and a dining area with a table and chairs.

A modern hotel lobby with a reception desk, seating area, and a dining space.

A living room with a stone fireplace, a flat-screen TV, and two yellow armchairs.

17. Days Inn by Wyndham Anderson

Anderson

Louis

฿1,954

฿2,169 total

includes taxes & fees

27 Sept - 28 Sept

A hotel dining area with a long table, multiple chairs, and a bar in the background.

A reception area with a counter, chairs, and a patterned rug.

A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.

18. Hampton Inn & Suites Seneca-Clemson Area

Seneca

kendra

฿4,067

฿4,474 total

includes taxes & fees

4 Oct - 5 Oct

A modern hotel lobby with a reception desk, seating area, and a large conference table.

A snack display with various packaged foods in a store.

A multi-story hotel with a parking lot in front.

A spacious lobby with a blue carpet, a wooden table with chairs, orange seating, a TV mounted on the wall, and a large arched window with a view.

19. Microtel Inn & Suites by Wyndham Anderson/Clemson

Anderson

Kathi

฿2,797

฿3,105 total

includes taxes & fees

29 Sept - 30 Sept

A modern hotel room with a large bed, a desk with a chair, a small table, and a nightstand with a lamp.

A gym with exercise equipment, a mirror, and a blue wall.

A laundry room with two stacked washers and dryers, grey tiled walls, and a light-colored floor.

A coffee station with two coffee machines, a coffee press, and various coffee pods and cups.

20. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Anderson

roxanne

฿3,656

฿4,058 total

includes taxes & fees

27 Sept - 28 Sept

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Top Keowee Hotel Reviews

Clemson University's James F. Martin Inn

10/10 Excellent

"10/10 as always!"

Inn @ Clemson

10/10 Excellent

"Clean..friendly staff.. conveniently located"

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

8/10 Good

"Nice bedding!"

Comfort Inn & Suites Clemson - University Area

10/10 Excellent

"Everything was wonderful ! The property and room were exceptionally clean. The staff was very friendly and helpful. Breakfast was great with many choices. I highly recommend staying here if in the Clemson area."

Courtyard Marriott Clemson

10/10 Excellent

"The staff were so friendly and accommodating. The property was very clean and room was spacious."

Quality Inn Seneca US-123

10/10 Excellent

"One of the cleanest room I’ve stayed in. The bed slept well and everything worked. The pool was so clean it sparkled. Nothing even floating in the top. The hotel is located in a busy area, but landscaped and built to allow some privacy We would definitely recommend and certainly will be back."

Horizon Inn & Suites

10/10 Excellent

"Great place"

Holiday Inn Anderson by IHG

10/10 Excellent

"The room was clean. Bathroom was nice and very clean. The air cooled the room fast. The property is in a great area. Shopping and dining with walking."

More cheap stays in Keowee

Quality Inn Clemson near University

3430 Clemson Blvd Anderson SC

฿1,852

฿2,056 total

30 Sept - 1 Oct

includes taxes & fees

Days Inn by Wyndham Anderson

1007 George Smith Mill Rd Anderson SC

฿1,954

฿2,169 total

27 Sept - 28 Sept

includes taxes & fees

Inn @ Clemson

1303 Tiger Blvd Clemson SC

฿2,662

฿2,955 total

23 Sept - 24 Sept

includes taxes & fees

8/10 Very good! (1,006 reviews)

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

฿3,370

฿3,741 total

24 Sept - 25 Sept

includes taxes & fees

Comfort Inn & Suites Clemson - University Area

1305 Tiger Blvd Clemson SC

฿3,475

฿3,857 total

18 Oct - 19 Oct

includes taxes & fees

8.4/10 Very good! (1,008 reviews)

Lakeside Lodge Clemson

13500 Clemson Blvd Seneca SC

฿3,623

฿4,497 total

30 Sept - 1 Oct

includes taxes & fees

Frequently asked questions

What's the best place to stay in Keowee?

Located 3.1 mi (4.9 km) from the heart of Keowee, Best Western Plus Clemson Hotel & Conference Center is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are Lakeside Lodge Clemson and Days Inn by Wyndham Anderson. See all available top hotels, or vacation rentals in Keowee.

If I need to cancel my hotel reservation in Keowee, will I receive a refund?

Yes, you'll find most hotel bookings are refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Keowee.

What is the top LGBTQ-friendly hotel in Keowee?

Tru by Hilton Seneca Clemson is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. See all available hotels listed as LGBTQ-friendly in Keowee.

What's the best dog-friendly hotel in Keowee?

Tru by Hilton Seneca Clemson is a top hotel for people travelling with their pets, and offers a fitness centre and laundry facilities for its human guests. See more pet-friendly hotel accommodations in Keowee.

What are some accommodation options with pools in Keowee?

Days Inn by Wyndham Anderson: Offers daily, a seasonal outdoor pool and free self parking. Best Western Plus Clemson Hotel & Conference Center and Quality Inn Seneca Clemson Area US-123 are a couple of other choices with an on-site pool. View all hotels with pools in Keowee.

How is it staying in Keowee?

Travellers to Keowee will find plenty to explore and enjoy. There are 1387 hotels and other accommodation options in the surrounding area. Find out more about Keowee.

What should I do while I'm visiting Keowee?

Places to visit in the wider area include Littlejohn Coliseum, Memorial Stadium and Fort Hill. You'll also find Walker Golf Course and Keowee Reservoir in the area. Take a look at what more there is to see and do in Expedia's Keowee guide.

What's the seasonal weather in Keowee?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Keowee is 1561 mm.

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Find hotels in Keowee, SC from ฿2,056

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Keowee

Check prices for these dates

Filter by

Star rating

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Our top choices for Keowee hotels

1. Tru by Hilton Seneca Clemson

2. Lakeside Lodge Clemson

3. Clemson University's James F. Martin Inn

4. Best Western Plus Clemson Hotel & Conference Center

5. The Shepherd Hotel Downtown Clemson

6. The Inn at Patrick Square

7. The Abernathy of Clemson

8. Hampton Inn Clemson-University Area

9. Comfort Inn & Suites Clemson - University Area

10. Holiday Inn Express & Suites Clemson by IHG

11. Courtyard Marriott Clemson

12. Fairfield Inn & Suites Seneca Clemson Univ Area

13. Inn @ Clemson

14. Best Western Seneca-Clemson

15. Quality Inn Seneca US-123

16. Liberty Hall Bed and Breakfast

17. Days Inn by Wyndham Anderson

18. Hampton Inn & Suites Seneca-Clemson Area

19. Microtel Inn & Suites by Wyndham Anderson/Clemson

20. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Top Keowee Hotel Reviews

Clemson University's James F. Martin Inn

Inn @ Clemson

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Comfort Inn & Suites Clemson - University Area

Courtyard Marriott Clemson

Quality Inn Seneca US-123

Horizon Inn & Suites

Holiday Inn Anderson by IHG

More cheap stays in Keowee

Quality Inn Clemson near University

Days Inn by Wyndham Anderson

Inn @ Clemson

Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

Lakeside Lodge Clemson

Frequently asked questions

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