Find hotels in Seneca, SC from ฿2,190
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Our top choices for Seneca hotels

Lakeside Lodge Clemson
Lakeside Lodge Clemson
Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123
Best Western Seneca-Clemson
Best Western Seneca-Clemson
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
Days Inn by Wyndham Seneca / Clemson Area
Days Inn by Wyndham Seneca / Clemson Area
Days Inn by Wyndham Anderson
Days Inn by Wyndham Anderson
Quality Inn & Suites Easley - Greenville
Quality Inn & Suites Easley - Greenville
Quality Inn Clemson near University
Quality Inn Clemson near University
Microtel Inn & Suites by Wyndham Anderson/Clemson
Microtel Inn & Suites by Wyndham Anderson/Clemson
Baymont by Wyndham Anderson Clemson
Baymont by Wyndham Anderson Clemson
Rodeway Inn Anderson North - Clemson
Rodeway Inn Anderson North - Clemson
Holiday Inn Anderson by IHG
Holiday Inn Anderson by IHG
Hampton Inn Hartwell
Hampton Inn Hartwell
Hilton Garden Inn Anderson
Hilton Garden Inn Anderson
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference Center
Carolina Camp Cedar
Carolina Camp CedarWhere to stay in Seneca
Serenity Bay
When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.
Downtown
If you're spending some time in Downtown, Seneca Historic District and Oconee County Library Seneca Branch are top sights worth seeing.
Pine Ridge Point
If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit Lake Keowee and Keowee Key Golf Course.
Indian Oaks
While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Oconee County Library Seneca Branch and Seneca Historic District.
Keowee Plantation
While Keowee Plantation isn't home to many top sights, Oconee County Library Seneca Branch and Seneca Historic District are some notable places to visit nearby.
Stay near popular Seneca attractions
Learn more about Seneca
Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

Top Seneca Hotel Reviews

Quality Inn Seneca Clemson Area US-123

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
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