Find hotels in Seneca, SC from ฿2,201

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4 Jan - 5 Jan
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5 Jan - 6 Jan
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9 Jan - 11 Jan
In two weeks
16 Jan - 18 Jan

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Our top choices for Seneca hotels

Lobby
Best Western Seneca-Clemson

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very good, (643)
"The stay was amazing "
United States
Tabatha
The price is ฿2,814
฿3,095 total
includes taxes & fees
11 Jan - 12 Jan
Best Western Seneca-Clemson
Balcony
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 star property
Seneca
9.4 out of 10, Exceptional, (205)
"Nice hotel by the lake"
United States
Mike
The price is ฿3,941
฿4,335 total
includes taxes & fees
11 Jan - 12 Jan
Fairfield Inn & Suites Seneca Clemson Univ Area
Exterior
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (53)
"Excellent stay."
United States
Beonca
The price is ฿2,385
฿4,010 total
includes taxes & fees
8 Jan - 9 Jan
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Exterior
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (670)
"Great place to stay"
United States
Jose
The price is ฿3,888
฿4,277 total
includes taxes & fees
15 Jan - 16 Jan
Hampton Inn & Suites Seneca-Clemson Area
Aerial view
Lakeside Lodge Clemson

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1000)
"Great place to stay. "
United States
Gene
The price is ฿3,436
฿4,266 total
includes taxes & fees
5 Jan - 6 Jan
Lakeside Lodge Clemson
Free daily on-the-go breakfast
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (666)
"Good available parking. Room clean. Breakfast was minimal, but good. The tub was slippery and needed a mat. I almost fell a couple of times. I would stay here again."
United States
Denise
The price is ฿2,383
฿2,811 total
includes taxes & fees
11 Jan - 12 Jan
Quality Inn Seneca Clemson Area US-123
Lobby
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (800)
"Staff is amazing, hotel and amenities are great. "
United States
Shannon
The price is ฿3,249
฿3,574 total
includes taxes & fees
11 Jan - 12 Jan
Tru by Hilton Seneca Clemson
Room, 1 King Bed, Non Smoking | Desk, free cots/infant beds, rollaway beds, free WiFi
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (722)
"Room was clean. Quiet place to rest. Lisa at the front desk was very helpful and very nice. "
United States
Teresa
The price is ฿2,331
฿2,564 total
includes taxes & fees
11 Jan - 12 Jan
Days Inn by Wyndham Seneca / Clemson Area
Restaurant
Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
4.0 star property
Pendleton
10.0 out of 10, Exceptional, (78)
"The owners are amazing. Comfy rooms, stellar breakfast and good people. "
United States
Renee
The price is ฿4,364
฿6,421 total
includes taxes & fees
17 Jan - 18 Jan
Liberty Hall Bed and Breakfast
Free daily continental breakfast
Quality Inn & Suites Easley - Greenville

Quality Inn & Suites Easley - Greenville

Quality Inn & Suites Easley - Greenville
2.5 star property
Easley
7.0 out of 10, Good, (390)
"The lady at the desk gave great customer service. The beds are comfortable. Easy getting downtown Greenville from here."
United States
Pamela
The price is ฿1,639
฿1,820 total
includes taxes & fees
10 Jan - 11 Jan
Quality Inn & Suites Easley - Greenville
Lobby
Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville
2.5 star property
Easley
7.4 out of 10, Good, (760)
"Easy access from the highway lot of restaurants around the hotel and staff is very friendly"
United States
brian
The price is ฿2,364
฿2,624 total
includes taxes & fees
5 Jan - 6 Jan
Baymont by Wyndham Easley/Greenville
Business centre
Days Inn by Wyndham Easley/Greenville/Clemson Area

Days Inn by Wyndham Easley/Greenville/Clemson Area

Days Inn by Wyndham Easley/Greenville/Clemson Area
2.0 star property
Easley
6.2 out of 10, (824)
"Friendly staff"
United States
Tina
The price is ฿2,186
฿2,427 total
includes taxes & fees
5 Jan - 6 Jan
Days Inn by Wyndham Easley/Greenville/Clemson Area
Signature Cottage, 2 Bedrooms, Non Smoking, Patio | Private kitchen | Fridge, microwave, oven, stovetop
Frank Howard 111 Farmhouse

Frank Howard 111 Farmhouse

Frank Howard 111 Farmhouse
3.0 star property
Clemson
9.8 out of 10, Exceptional, (10)
"Great stay "
United States
Johnny
The price is ฿3,121
฿7,838 total
includes taxes & fees
13 Jan - 14 Jan
Frank Howard 111 Farmhouse
In-room safe, blackout curtains, soundproofing, iron/ironing board
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
Clemson
9.8 out of 10, Exceptional, (746)
"Staff was amazing and our room was clean and comfortable. "
United States
Amanda R
The price is ฿5,643
฿6,264 total
includes taxes & fees
5 Jan - 6 Jan
The Shepherd Hotel Downtown Clemson
Property amenity
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very good, (1003)
"Clean room and staff were great’"
United States
Audrey
The price is ฿2,921
฿3,242 total
includes taxes & fees
6 Jan - 7 Jan
Best Western Plus Clemson Hotel & Conference Center
Lobby lounge
Inn @ Clemson

Inn @ Clemson

Inn @ Clemson
2.5 star property
Clemson
8.0 out of 10, Very good, (1003)
"Staff and hotel was amazing "
United States
Keren
Inn @ Clemson
Fireplace
Courtyard Marriott Clemson

Courtyard Marriott Clemson

Courtyard Marriott Clemson
3.0 star property
Clemson
9.2 out of 10, Wonderful, (525)
"Overall, great stay!"
United States
Lynn
The price is ฿3,725
฿4,134 total
includes taxes & fees
8 Jan - 9 Jan
Courtyard Marriott Clemson
Exterior
Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
2.5 star property
Clemson
8.8 out of 10, Excellent, (951)
"Had a great stay at this hotel. Conveniently located near restaurants. "
United States
Kelly
The price is ฿3,720
฿4,129 total
includes taxes & fees
10 Jan - 11 Jan
Holiday Inn Express & Suites Clemson by IHG
View from property
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.6 out of 10, Exceptional, (961)
"Great place to stay!"
United States
Mindi
The price is ฿4,697
฿5,214 total
includes taxes & fees
5 Jan - 6 Jan
Clemson University's James F. Martin Inn
Lobby
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.2 out of 10, Very good, (1001)
"Great area behind the hotel to walk my dog!!"
United States
Connie
The price is ฿3,234
฿3,590 total
includes taxes & fees
13 Jan - 14 Jan
Comfort Inn & Suites Clemson - University Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Seneca

Find the best Seneca areas for the activities you enjoy most.

Serenity Bay

When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.

Downtown

If you're spending some time in Downtown, Seneca Historic District and Oconee County Library Seneca Branch are top sights worth seeing.

Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit Lake Keowee and Keowee Key Golf Course.

Indian Oaks

While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Oconee County Library Seneca Branch and Seneca Historic District.

Keowee Plantation

While Keowee Plantation isn't home to many top sights, Oconee County Library Seneca Branch and Seneca Historic District are some notable places to visit nearby.

Stay near popular Seneca attractions

High Shoals Falls in South Mountains State Park

High Falls County Park

Nestled along Lake Keowee with the Blue Ridge Mountains as backdrop, High Falls County Park offers pristine swimming and camping spots. Reserve waterfront campsites early to enjoy the park's serene natural setting.
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Lovely shot of the Blue Ridge Mountains in the distance, with a rural pasture in the foreground, in late summer when the grass is starting to turn yellow and brown. Upstate South Carolina scene.

Blue Ridge Field

This historic park honours African-American education in Oconee County on the former Blue Ridge High School football grounds. Stroll the paved loop trail and explore community gardens in this peaceful green space.
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Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

See all hotels in Seneca
Lake Keowee South Carolina

Top Seneca Hotel Reviews

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

10/10 Excellent
"Good available parking. Room clean. Breakfast was minimal, but good. The tub was slippery and needed a mat. I almost fell a couple of times. I would stay here again."
Denise 6-night trip
Posted 6 days ago
Quality Inn Seneca Clemson Area US-123
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

10/10 Excellent
"Excellent stay."
Beonca 1-night trip
Posted 9 days ago
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

More cheap stays in Seneca

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

1007 George Smith Mill Rd Anderson SC
The price is ฿1,983 per night from 6 Jan to 7 Jan
฿1,983
฿2,201 total
6 Jan - 7 Jan
includes taxes & fees
7.6/10 Good! (1,003 reviews)

Frequently asked questions

Where is the best place for a stay in Seneca?
Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel offers free breakfast and free parking. Traveller reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
What's the best family accommodation in Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Also, attractions in the area such as Ultimate Action Sports are fun for the whole family. Find more child-friendly accommodations in Seneca.
What is the top LGBTQ-friendly accommodation in Seneca?
Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Tru by Hilton Seneca Clemson is another good choice for your trip. See all available hotels listed as LGBTQ-friendly in Seneca.
What's the best dog-friendly hotel in Seneca?
Lakeside Lodge Clemson is a top hotel for people travelling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices for you and your pet's trip include Days Inn by Wyndham Seneca / Clemson Area and Tru by Hilton Seneca Clemson. See more pet-friendly hotel accommodations in Seneca.
What are some hotels with pools in Seneca?
Lakeside Lodge Clemson: Hotel located near Clemson University. Features free self parking, a seasonal outdoor pool and complimentary wireless Internet access. Quality Inn Seneca Clemson Area US-123 and Hampton Inn & Suites Seneca-Clemson Area are two additional hotels that feature an on-site pool. View all hotels with pools in Seneca.
What is staying in Seneca like?
Visitors to Seneca will definitely enjoy the sporting events, lakeside setting and university setting. Welcoming and scenic, this city also attracts tourists with its cafes. In Seneca, there are 290 hotels and other accommodation options to choose from. Find out more about Seneca.
What should I see while I'm in Seneca?
Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Keowee Reservoir, Lake Keowee and Lake Hartwell. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Take a look at what more there is to see and do in Expedia's Seneca guide.
What's the seasonal weather in Seneca?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Seneca is 1565 mm.

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