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Search Hotels in Illinois Medical District, Chicago

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Our top choices for Illinois Medical District hotels

1. Hyatt House Chicago Medical/University District

Hyatt House Chicago Medical/University District
3.5 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,550 reviews)
"Great hotel!"
United States
Bianca
The price is ฿5,975
฿7,103 total
includes taxes & fees
30 Jun - 1 Jul
Hyatt House Chicago Medical/University District

2. Hampton Inn & Suites Chicago Medical District UIC

Hampton Inn & Suites Chicago Medical District UIC
2.5 star property
Illinois Medical District
9.6 out of 10, Exceptional, (631 reviews)
"Fantastic location. Extremely happy with accommodations."
United States
Guadalupe
The price is ฿5,311
฿6,314 total
includes taxes & fees
30 Jun - 1 Jul
Hampton Inn & Suites Chicago Medical District UIC

3. Hyatt Place Chicago Medical/University District

Hyatt Place Chicago Medical/University District
3.0 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,484 reviews)
"Loved this hotel and location. Very well appointed for the price and the staff was great."
United States
Timothy
The price is ฿6,142
฿7,302 total
includes taxes & fees
30 Jun - 1 Jul
Hyatt Place Chicago Medical/University District

4. Freehand Chicago

Freehand Chicago
4.0 star property
River North, 4.7 km from Illinois Medical District
7.8 out of 10, Good, (3,129 reviews)
"It was good place to stay for the Go Fest Event"
United States
Ken
The price is ฿3,811
฿6,118 total
includes taxes & fees
5 Jul - 6 Jul
Freehand Chicago

5. Palmer House a Hilton Hotel

Palmer House a Hilton Hotel
4.0 star property
Theatre District, 4.2 km from Illinois Medical District
8.6 out of 10, Excellent, (2,498 reviews)
"Beautiful place to stay."
United States
Charles Otto
The price is ฿7,473
฿9,876 total
includes taxes & fees
2 Jul - 3 Jul
Palmer House a Hilton Hotel

6. The Chicago Hotel Collection Ambassador Gold Coast

The Chicago Hotel Collection Ambassador Gold Coast
4.0 star property
Gold Coast, 5.6 km from Illinois Medical District
8.2 out of 10, Very good, (1,643 reviews)
"Very good location, breakfast is fantastic, dinner and bar are great."
United States
Zhiwen
The price is ฿4,107
฿4,883 total
includes taxes & fees
5 Jul - 6 Jul
The Chicago Hotel Collection Ambassador Gold Coast

7. Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel

Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel
4.0 star property
The Loop, 3.8 km from Illinois Medical District
9.6 out of 10, Exceptional, (1,253 reviews)
"The best place I’ve stayed in Chicago"
United States
Robyn
The price is ฿6,639
฿7,893 total
includes taxes & fees
5 Jul - 6 Jul
Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel

8. Hyatt Regency Chicago

Hyatt Regency Chicago
4.0 star property
The Loop, 4.8 km from Illinois Medical District
9.4 out of 10, Exceptional, (3,435 reviews)
"Staff was great."
United States
Marianne
The price is ฿7,980
฿10,677 total
includes taxes & fees
9 Jul - 10 Jul
Hyatt Regency Chicago

9. River Hotel

River Hotel
4.0 star property
The Loop, 4.6 km from Illinois Medical District
8.8 out of 10, Excellent, (5,258 reviews)
"Excellent place to stay, as we found it central & walkable to most parks & attractions. The place was spotless & the staff were fantastic."
Canada
Jody
The price is ฿5,191
฿6,172 total
includes taxes & fees
5 Jul - 6 Jul
River Hotel

10. Staypineapple, An Iconic Hotel, The Loop

Staypineapple, An Iconic Hotel, The Loop
4.0 star property
Theatre District, 4.2 km from Illinois Medical District
9.4 out of 10, Exceptional, (1,116 reviews)
"Good location, friendly staff"
United Kingdom
Philip
The price is ฿5,296
฿7,285 total
includes taxes & fees
6 Jul - 7 Jul
Staypineapple, An Iconic Hotel, The Loop

11. Eurostars Magnificent Mile

Eurostars Magnificent Mile
4.0 star property
River North, 4.8 km from Illinois Medical District
9.0 out of 10, Wonderful, (3,676 reviews)
"Had an amazing stay here!"
United States
Audrey
The price is ฿5,391
฿6,409 total
includes taxes & fees
2 Jul - 3 Jul
Eurostars Magnificent Mile

12. Arlo Chicago

Arlo Chicago
4.0 star property
Theatre District, 4.5 km from Illinois Medical District
9.4 out of 10, Exceptional, (2,130 reviews)
"Excellent hotel! Will definitely stay again."
United States
Justin
The price is ฿6,575
฿8,826 total
includes taxes & fees
2 Jul - 3 Jul
Arlo Chicago

13. Congress Plaza Hotel

Congress Plaza Hotel
3.5 star property
The Loop, 4.2 km from Illinois Medical District
8.0 out of 10, Very good, (10,128 reviews)
"Great stay!"
United States
Daniel
The price is ฿4,550
฿5,410 total
includes taxes & fees
30 Jun - 1 Jul
Congress Plaza Hotel

14. The Godfrey Hotel Chicago

The Godfrey Hotel Chicago
4.5 star property
River North, 4.6 km from Illinois Medical District
8.8 out of 10, Excellent, (2,279 reviews)
"Would definitely stay there again"
United States
Benjy
The price is ฿4,837
฿6,500 total
includes taxes & fees
6 Jul - 7 Jul
The Godfrey Hotel Chicago

15. Hilton Chicago/Magnificent Mile Suites

Hilton Chicago/Magnificent Mile Suites
3.5 star property
Streeterville, 5.6 km from Illinois Medical District
9.0 out of 10, Wonderful, (4,458 reviews)
"Great stay!"
United States
Avradita
The price is ฿5,334
฿6,342 total
includes taxes & fees
6 Jul - 7 Jul
Hilton Chicago/Magnificent Mile Suites

16. Silversmith Hotel Chicago Downtown

Silversmith Hotel Chicago Downtown
4.0 star property
Theatre District, 4.2 km from Illinois Medical District
9.2 out of 10, Wonderful, (2,258 reviews)
"Wonderful stay"
United States
Taylor
The price is ฿4,549
฿6,426 total
includes taxes & fees
5 Jul - 6 Jul
Silversmith Hotel Chicago Downtown

17. Omni Chicago Hotel

Omni Chicago Hotel
4.5 star property
Streeterville, 5 km from Illinois Medical District
9.2 out of 10, Wonderful, (1,824 reviews)
"All around great property and a wonderful location"
United States
Bruce
The price is ฿5,098
฿7,171 total
includes taxes & fees
7 Jul - 8 Jul
Omni Chicago Hotel

18. FOUND Hotel Chicago River North

FOUND Hotel Chicago River North
2.0 star property
River North, 4.3 km from Illinois Medical District
8.4 out of 10, Very good, (648 reviews)
"Excellent stay in good location"
United States
Nicholas
The price is ฿4,474
฿5,252 total
includes taxes & fees
30 Jun - 1 Jul
FOUND Hotel Chicago River North

19. Hotel 55 Chicago Downtown

Hotel 55 Chicago Downtown
4.0 star property
River North, 4.9 km from Illinois Medical District
8.8 out of 10, Excellent, (1,565 reviews)
"Great stay"
United States
Matt
The price is ฿4,470
฿6,306 total
includes taxes & fees
1 Jul - 2 Jul
Hotel 55 Chicago Downtown

20. Central Loop Hotel

Central Loop Hotel
4.0 star property
Theatre District, 3.8 km from Illinois Medical District
8.6 out of 10, Excellent, (2,192 reviews)
"Great hotel with awesome location"
United States
Daniel
The price is ฿4,421
฿5,256 total
includes taxes & fees
1 Jul - 2 Jul
Central Loop Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Illinois Medical District

Find the best Illinois Medical District areas for the activities you enjoy most.

Downtown Chicago

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

Magnificent Mile

Shopaholics need look no further this glittering street packed with boutique and luxury shops, famous department stores and cafes.

The Loop

Bordered roughly by the surrounding elevated train circuit, this Chicago neighborhood has restaurants, galleries, parks and a giant silver bean.

River North

Known for its fantastic nightlife, stunning river views and popular shops, there's plenty to explore in River North. Top attractions like Merchandise Mart and Bally's Casino Chicago are major draws. Catch the metro at Merchandise Mart Station or Chicago Station (Brown Line) to see more of the city.

Lincoln Park

Both a neighborhood and a park, this northern Chicago area has gorgeous scenery, residential streets lined with stately homes and extensive shopping and dining.

Top Illinois Medical District Hotel Reviews

Frequently asked questions

What's it like in Illinois Medical District?
Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighbourhood has to offer.
Where is the best place to stay in Illinois Medical District?
Based on Expedia customer reviews, Hampton Inn & Suites Chicago Medical District UIC is the highest ranked property in Illinois Medical District. This hotel is a short 15-minute walk from United Center, and it offers free breakfast and an indoor pool. Other top choices in the neighbourhood include Hyatt House Chicago Medical/University District and Hyatt Place Chicago Medical/University District.
How many hotels are there in the Illinois Medical District area?
If you're searching for places to stay in Chicago, choose from one of Expedia's 16 hotels and other accommodation options in Illinois Medical District.
If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Illinois Medical District.
What can I see and do in this Chicago neighbourhood?
Don't miss favourite places to visit in the surrounding area, such as Soldier Field, Michigan Avenue and United Center. Malcolm X College and Michael Jordan Statue are also worth a visit when you're out sightseeing in Chicago.
How can I get around Illinois Medical District and the greater Chicago area?
Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.