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20 Dec - 21 Dec
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Our top choices for Houston Natural Science Museum hotels

Breakfast, lunch, dinner served; American cuisine
Hotel Saint Augustine

Hotel Saint Augustine

Hotel Saint Augustine
3.5 star property
Montrose, 1.7 km from Houston Natural Science Museum
9.6 out of 10, Exceptional, (68)
"We have stayed at the hotel many times and always enjoy being here. "
United States
David
The price is ฿8,452
฿9,967 total
includes taxes & fees
3 Jan - 4 Jan 2026
Hotel Saint Augustine
Exterior
La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B
3.5 star property
Midtown, 2.9 km from Houston Natural Science Museum
9.8 out of 10, Exceptional, (542)
"great neighborhood, friendly staff, and delicious breakfast"
United States
Anna
The price is ฿5,622
฿6,578 total
includes taxes & fees
22 Dec - 23 Dec
La Maison in Midtown an urban B&B
Terrace/patio
Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX
3.0 star property
Texas Medical Center, 2 km from Houston Natural Science Museum
9.4 out of 10, Exceptional, (1001)
"Clean room and nice staff"
Canada
Guillermo
The price is ฿3,065
฿3,586 total
includes taxes & fees
28 Dec - 29 Dec
Hilton Garden Inn Houston Medical Center, TX
Terrace/patio
Home2 Suites by Hilton Houston Medical Center, TX

Home2 Suites by Hilton Houston Medical Center, TX

Home2 Suites by Hilton Houston Medical Center, TX
3.0 star property
Texas Medical Center, 2 km from Houston Natural Science Museum
9.4 out of 10, Exceptional, (566)
"Everything was good "
United States
cheryl
The price is ฿3,580
฿4,188 total
includes taxes & fees
29 Dec - 30 Dec
Home2 Suites by Hilton Houston Medical Center, TX
Premium bedding, pillow-top beds, minibar, in-room safe
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
0.3 km from Houston Natural Science Museum
9.0 out of 10, Wonderful, (1857)
"Very nice room, great staff, excellent food & drink."
United States
Mary
The price is ฿8,515
฿11,315 total
includes taxes & fees
21 Dec - 22 Dec
Hotel Zaza Houston Museum District
Outdoor pool, free pool cabanas, pool umbrellas
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
Texas Medical Center, 1.8 km from Houston Natural Science Museum
9.2 out of 10, Wonderful, (1022)
"Excellent breakfast and bar"
United States
Misty
The price is ฿4,061
฿5,054 total
includes taxes & fees
21 Dec - 22 Dec
The Westin Houston Medical Center/Museum District
Reception
La Colombe d'Or Hotel

La Colombe d'Or Hotel

La Colombe d'Or Hotel
5.0 star property
Montrose, 2.2 km from Houston Natural Science Museum
9.4 out of 10, Exceptional, (147)
"Room was great, staff good. Quiet and clean."
United States
Emmett
The price is ฿13,589
฿15,899 total
includes taxes & fees
22 Dec - 23 Dec
La Colombe d'Or Hotel
Exterior
InterContinental Houston by IHG

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
Texas Medical Center, 2.2 km from Houston Natural Science Museum
9.2 out of 10, Wonderful, (1005)
"Very clean room very polite staff"
United States
David
The price is ฿4,353
฿5,721 total
includes taxes & fees
23 Dec - 24 Dec
InterContinental Houston by IHG
American cuisine
Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
Texas Medical Center, 1.7 km from Houston Natural Science Museum
9.0 out of 10, Wonderful, (1001)
"Comfortable bed, very clean, very good food, quite, friendly stuff and hotel shuttle works easy."
United States
Elena
The price is ฿4,245
฿5,962 total
includes taxes & fees
9 Jan - 10 Jan 2026
Houston Marriott Medical Center/Museum District
Lobby
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center
3.0 star property
Texas Medical Center, 3 km from Houston Natural Science Museum
9.2 out of 10, Wonderful, (2195)
"Comfortable room and nice breakfast in close proximity to Houston’s medical center. "
United States
Stephen
The price is ฿3,444
฿4,051 total
includes taxes & fees
23 Dec - 24 Dec
Hyatt Place Houston Medical Center
Lobby
Hyatt House Houston Medical Center

Hyatt House Houston Medical Center

Hyatt House Houston Medical Center
3.0 star property
Texas Medical Center, 3 km from Houston Natural Science Museum
9.2 out of 10, Wonderful, (1197)
"We were here for a rugby tournament and the staff kept up with everything very well"
United States
Jessica Lynn
The price is ฿3,444
฿4,051 total
includes taxes & fees
23 Dec - 24 Dec
Hyatt House Houston Medical Center
Lobby
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center, 2.7 km from Houston Natural Science Museum
9.0 out of 10, Wonderful, (3608)
"Great hotel I would definitely stay again"
United States
Newassa
The price is ฿3,484
฿4,076 total
includes taxes & fees
18 Jan - 19 Jan 2026
Blossom Hotel Houston, Curio Collection by Hilton
Fridge, microwave, stovetop, cookware/dishes/utensils
Modern B & B

Modern B & B

Modern B & B
3.5 star property
Montrose, 2.3 km from Houston Natural Science Museum
9.0 out of 10, Wonderful, (207)
"Fresh breakfast and friendly"
United States
Stephen
The price is ฿3,533
฿4,134 total
includes taxes & fees
23 Dec - 24 Dec
Modern B & B
Terrace/patio
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
1.8 km from Houston Natural Science Museum
8.4 out of 10, Very good, (1773)
"Loved the room, clean, friendly staff. Would reccomend :)"
United States
Rolando
The price is ฿2,702
฿3,198 total
includes taxes & fees
25 Dec - 26 Dec
Hilton Houston Plaza/Medical Center
Breakfast and dinner served
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
Texas Medical Center, 2.2 km from Houston Natural Science Museum
8.4 out of 10, Very good, (478)
"Solid hotel and amenities"
United States
Kenneth
The price is ฿3,493
฿4,086 total
includes taxes & fees
25 Dec - 26 Dec
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Interior
Wanderstay Houston Hostel

Wanderstay Houston Hostel

Wanderstay Houston Hostel
2.0 star property
Museum District, 1.9 km from Houston Natural Science Museum
8.4 out of 10, Very good, (188)
"This is an amazing place to stay."
United States
Darius
The price is ฿1,803
฿2,110 total
includes taxes & fees
21 Dec - 22 Dec
Wanderstay Houston Hostel
Reception
Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown
2.0 star property
1.3 km from Houston Natural Science Museum
8.0 out of 10, Very good, (1001)
"Nice hotel"
United States
Robert Jeanmard
The price is ฿2,607
฿3,050 total
includes taxes & fees
21 Dec - 22 Dec
Americas Best Value Inn Medical Center Downtown
Lobby
MainStay Suites Texas Medical Center/Reliant Park

MainStay Suites Texas Medical Center/Reliant Park

MainStay Suites Texas Medical Center/Reliant Park
2.5 star property
Astrodome, 2.7 km from Houston Natural Science Museum
7.6 out of 10, Good, (1003)
"Safe and family friendly"
United States
Bishnu
The price is ฿1,976
฿2,468 total
includes taxes & fees
26 Dec - 27 Dec
MainStay Suites Texas Medical Center/Reliant Park
Standard Room, 1 King Bed | Laptop workspace, blackout curtains, soundproofing, iron/ironing board
Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
Midtown, 3.1 km from Houston Natural Science Museum
7.8 out of 10, Good, (37)
"Check in staff was friendly and room was clean."
United States
Alfredo
The price is ฿2,685
฿3,142 total
includes taxes & fees
21 Dec - 22 Dec
Downtowner Inns - Houston Downtown
Coffee service
Summit Inn - Houston Medical Center

Summit Inn - Houston Medical Center

Summit Inn - Houston Medical Center
2.0 star property
Astrodome, 2.7 km from Houston Natural Science Museum
7.4 out of 10, Good, (392)
"the location "
United States
Jorge
The price is ฿1,628
฿1,905 total
includes taxes & fees
21 Dec - 22 Dec
Summit Inn - Houston Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Houston Natural Science Museum Hotel Reviews

InterContinental Houston by IHG

InterContinental Houston by IHG

10/10 Excellent
"Courteous staff. Clean room with nice amenities. Great location. "
Angela 2-night trip
Posted 2 days ago
InterContinental Houston by IHG

Hotels near other Houston Natural Science Museum attractions

Museum of Fine Arts Houston - Kinder building architecture

Houston Museum of Fine Arts

4.7/5 (250 reviews)
Architecturally stunning and filled with pieces by renowned artists of the world, this museum is a must-see for art lovers.
See properties
The most happening place for toddlers in houston
Photo by Mariam Ahmed
Open Photo by Mariam Ahmed

Children's Museum of Houston

You can take time to visit Children's Museum of Houston during your travels to Houston. Experience the area's fascinating museums and entertainment choices.
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Frequently asked questions

What's the area like around Houston Natural Science Museum?
Houston Natural Science Museum is located in an area of Houston known for its top museums and popular art scene. If you're looking for a convenient place to stay, take a look at the 193 hotels and other accommodation options you'll find within a mile.
What's the best place to stay near Houston Natural Science Museum?
Adjacent to Houston Natural Science Museum, Hotel Zaza Houston Museum District is one of the top choices for your stay based on our traveller data, and this aparthotel offers a full-service spa and a restaurant. Other good options within a short distance include Americas Best Value Inn Medical Center Downtown and Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only.
How many hotels should I expect to find near Houston Natural Science Museum?
Expedia has 193 hotels and other accommodation options within a mile from Houston Natural Science Museum.
If I need to cancel the hotel reservation for my stay near Houston Natural Science Museum, will I receive a refund?
Yes! Most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the best deals available near Houston Natural Science Museum.
What can I see and do near Houston Natural Science Museum?
You might want to spend some time browsing the exhibits at Houston Museum of Fine Arts, Menil Collection or Buffalo Soldiers National Museum. Sights like NRG Park, 2209 Dowling Street and Eldorado Ballroom are must-sees while exploring the area. You can catch a show at Midtown Arts and Theater Center Houston, Main Street Theater - Rice Village and House of Blues Houston.
How can I get to Houston Natural Science Museum?
You can access metro transport at Palm Center Transit Center, MacGregor Park/Martin Luther King Jr. Station and UH South/University Oaks Station. If you'd like to venture farther outside of the area, consider renting a car to take in more sights.