Santa Maria Travel Guide

Guayaquil

Things to do

Half Day Walking Tour of Guayaquil Pearl of the Pacific

Half Day Walking Tour of Guayaquil Pearl of the Pacific

฿3,280
per adult
Half Day Walking Tour of Guayaquil Pearl of the Pacific
Guayaquil: City Highlights Tour with Cable Car Ride

Guayaquil: City Highlights Tour with Cable Car Ride

฿4,001
per adult
Guayaquil: City Highlights Tour with Cable Car Ride
City Winery - Two Hemispheres

Wine Tasting Experience with Tasting Menu

฿2,115
per adult
100% of travellers recommend
Wine Tasting Experience with Tasting Menu
Cocoa farm and Chocolate making!

Cocoa farm and Chocolate making!

฿5,084
per adult
Cocoa farm and Chocolate making!
Private city tour in Guayaquil - Iguana Park

Guayaquil Private Experience - City Tour for Seniors

฿5,576
per adult
Guayaquil Private Experience - City Tour for Seniors
Ecuador Paragliding Montañita

Ecuador Paragliding Montañita

฿2,132
per adult
Ecuador Paragliding Montañita
See all activities in Guayaquil

Top hotels in Santa Maria

Oro Verde Guayaquil

Oro Verde Guayaquil

5 out of 5
9 De Octubre Y Garcia Moreno Guayaquil Guayas
The price is ฿3,074 per night from 19 Sept to 20 Sept
฿3,074
฿3,464 total
19 Sept - 20 Sept
Stay at this luxury hotel in Guayaquil. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the helpful staff in their ...
9.6/10 Exceptional! (1,004 reviews)
"Wonderful hotel, food is excellent, staff is wonderful, shuttle is on point and ready for me. Could not complain with this hotel, to me it is perfect. I stay here every time I go to Guayaquil. Recommend this hotel 120%!!!!!"

Reviewed on 13 Sept 2026

Oro Verde Guayaquil
Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N Guayaquil Guayas
The price is ฿3,807 per night from 27 Sept to 28 Sept
฿3,807
฿4,271 total
27 Sept - 28 Sept
Stay at this luxury hotel in Guayaquil. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
Wyndham Guayaquil Puerto Santa Ana
Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

3.5 out of 5
Av. de Las Américas,junto al Aeropuerto Guayaquil Guayas
The price is ฿3,371 per night from 11 Oct to 12 Oct
฿3,371
฿3,791 total
11 Oct - 12 Oct
Stay at this business-friendly hotel in Guayaquil. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,001 reviews)
"The best choice next to the airport"

Reviewed on 10 Sept 2026

Holiday Inn Guayaquil Airport by IHG
Hilton Colon Guayaquil

Hilton Colon Guayaquil

4.5 out of 5
Av Francisco de Orellana Mz 111 Guayaquil
Fully refundableReserve now, pay when you stay
The price is ฿3,523 per night from 26 Sept to 27 Sept
฿3,523
฿3,958 total
26 Sept - 27 Sept
Stay at this luxury hotel in Guayaquil. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
Hilton Colon Guayaquil
Wyndham Garden Guayaquil

Wyndham Garden Guayaquil

3.5 out of 5
Juan Tanca Marengo Ave Guayaquil Guayas
The price is ฿2,975 per night from 9 Oct to 10 Oct
฿2,975
฿3,322 total
9 Oct - 10 Oct
Stay at this business-friendly hotel in Guayaquil. Enjoy free Wi-Fi, free parking and 2 restaurants. Our guests praise the breakfast and the helpful staff in ...
9.2/10 Wonderful! (1,001 reviews)
"Todo exelente"

Reviewed on 10 Sept 2026

Wyndham Garden Guayaquil
TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport

4.5 out of 5
Av. Joaquín Orrantia y L. Benitez Guayaquil Guayas
The price is ฿3,305 per night from 19 Sept to 20 Sept
฿3,305
฿3,718 total
19 Sept - 20 Sept
Stay at this luxury hotel in Guayaquil. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the breakfast and the helpful staff in their reviews. ...
TRYP by Wyndham Guayaquil Airport
See all 450 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Maria

Find the best Santa Maria areas for the activities you enjoy most.
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

A colorful outdoor installation with large letters spelling out a word.
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Artisan Market while you're in town.

A densely packed urban area with numerous buildings and a prominent tower on a hill.

Puerto Santa Ana

Restaurants and river views are some things travellers note about Puerto Santa Ana. Check out Santa Ana Hill or Numa Pompilio Llona Street while you're familiarising yourself with the larger area.

A cityscape with colorful buildings, a prominent church, and a hill with residential structures.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.

A green and yellow iguana on a rocky surface.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Policentro.

Santa Maria Travel Guide