Santa Maria Travel Guide

Guayaquil

Things to do

Guayaquil: City Highlights Tour with Cable Car Ride

Guayaquil: City Highlights Tour with Cable Car Ride

฿3,876
per adult
Guayaquil: City Highlights Tour with Cable Car Ride
Half Day Walking Tour of Guayaquil Pearl of the Pacific

Half Day Walking Tour of Guayaquil Pearl of the Pacific

฿3,285
per adult
Half Day Walking Tour of Guayaquil Pearl of the Pacific
City Winery - Two Hemispheres

Wine Tasting Experience with Tasting Menu

฿2,119
per adult
100% of travellers recommend
Wine Tasting Experience with Tasting Menu
Private city tour in Guayaquil - Iguana Park

Guayaquil Experience - Premium City Tour

฿4,928
per adult
Guayaquil Experience - Premium City Tour
Cocoa farm and Chocolate making!

Cocoa farm and Chocolate making!

฿5,092
per adult
Cocoa farm and Chocolate making!
San Francisco Plaza

Shared Walking Tour in Guayaquil City

฿1,643
per adult
Shared Walking Tour in Guayaquil City
See all activities in Guayaquil

Top hotels in Santa Maria

Hilton Colon Guayaquil

Hilton Colon Guayaquil

4.5 out of 5
Av Francisco de Orellana Mz 111 Guayaquil
The price is ฿3,662 per night from 4 Jul to 5 Jul
฿3,662
฿4,112 total
4 Jul - 5 Jul
Stay at this luxury hotel in Guayaquil. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
8.8/10 Excellent! (931 reviews)
"💯"

Reviewed on 23 Jun 2026

Hilton Colon Guayaquil
Oro Verde Guayaquil

Oro Verde Guayaquil

5 out of 5
9 De Octubre Y Garcia Moreno Guayaquil Guayas
The price is ฿2,844 per night from 26 Jun to 27 Jun
฿2,844
฿3,211 total
26 Jun - 27 Jun
Stay at this luxury hotel in Guayaquil. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the helpful staff in their ...
9.6/10 Exceptional! (1,003 reviews)
"C"

Reviewed on 25 Jun 2026

Oro Verde Guayaquil
Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N Guayaquil Guayas
The price is ฿3,011 per night from 5 Jul to 6 Jul
฿3,011
฿3,395 total
5 Jul - 6 Jul
Stay at this luxury hotel in Guayaquil. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
9.2/10 Wonderful! (1,005 reviews)
"Excelente"

Reviewed on 25 Jun 2026

Wyndham Guayaquil Puerto Santa Ana
Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

3.5 out of 5
Av. de Las Américas,junto al Aeropuerto Guayaquil Guayas
The price is ฿3,211 per night from 11 Jul to 12 Jul
฿3,211
฿3,616 total
11 Jul - 12 Jul
Stay at this business-friendly hotel in Guayaquil. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,004 reviews)
"Good place to stay, clean, confortable and good food"

Reviewed on 24 Jun 2026

Holiday Inn Guayaquil Airport by IHG
Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels

4 out of 5
Clemente Ballén 406 Guayaquil Guayas
The price is ฿2,225 per night from 25 Jul to 26 Jul
฿2,225
฿2,531 total
25 Jul - 26 Jul
Stay at this business-friendly hotel in Guayaquil. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the comfy rooms ...
9.2/10 Wonderful! (1,001 reviews)
"Tuve una buena experiencia en el Hotel Unipark. Es un hotel que ya tiene algunos años, pero se encuentra bien mantenido y ofrece una muy buena relación calidad-precio. Las habitaciones son cómodas, las amenidades cumplen con lo necesario y la ubicación es uno de sus mayores atractivos. Además, se ..."

Reviewed on 24 Jun 2026

Unipark by Oro Verde Hotels
Wyndham Garden Guayaquil

Wyndham Garden Guayaquil

3.5 out of 5
Juan Tanca Marengo Ave Guayaquil Guayas
The price is ฿2,499 per night from 27 Jun to 28 Jun
฿2,499
฿2,799 total
27 Jun - 28 Jun
Stay at this business-friendly hotel in Guayaquil. Enjoy free Wi-Fi, free parking and 2 restaurants. Our guests praise the breakfast and the helpful staff in ...
9.2/10 Wonderful! (1,003 reviews)
"Very happy !"

Reviewed on 24 Jun 2026

Wyndham Garden Guayaquil
See all 435 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Maria

Find the best Santa Maria areas for the activities you enjoy most.
Fachada colorida de estilo colonial, barrio de Santa Ana, Guayaquil, Ecuador

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

Vista panorámica de las favelas de cerro santa ana, guayaquil, ecuador

Puerto Santa Ana

Restaurants and river views are some things travellers note about Puerto Santa Ana. Check out Santa Ana Hill or Artisan Market while you're familiarising yourself with the larger area.

Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and La Rotonda while you're in town.

Cityscape from Malecón 2000, the boardwalk overlooking the Guayas River in Guayaquil, Ecuador's largest city and economic capital.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.

Garzota

The restaurants and shopping are a few reasons travellers visit Garzota. Though there aren't many top sights in the neighbourhood, you can visit Mall del Sol Shopping Center and City Mall, a few notable attractions nearby.

Santa Maria Travel Guide