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Our top choices for Santa Maria hotels

Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport
4.0 star property
Garzota, 4.9 km from Santa Maria
8.6 out of 10, Excellent, (267 reviews)
"Very clean and comfortable rooms. The staff was very friendly and they're all fluent in English and Spanish. Breakfast in the restaurant was also delicious."
United States
Myna-Maria
The price is ฿2,045
฿2,299 total
26 Jun - 27 Jun
Hotel Puerto Pacifico Guayaquil Airport

Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 6.9 km from Santa Maria
9.6 out of 10, Exceptional, (1,002 reviews)
"Great place to stay"
United States
Daniel
The price is ฿2,787
฿3,148 total
21 Jun - 22 Jun
Oro Verde Guayaquil

Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 4.8 km from Santa Maria
9.2 out of 10, Wonderful, (1,001 reviews)
"The room was really clean and the staff in the lobby were really helpful. Breakfast was good"
United States
Rosa
The price is ฿2,466
฿2,761 total
20 Jun - 21 Jun
Wyndham Garden Guayaquil

DC Suites Aeropuerto

DC Suites Aeropuerto
3.0 star property
Simón Bolívar, 5.2 km from Santa Maria
9.0 out of 10, Wonderful, (638 reviews)
"Great place to stay. Walking distance to airport."
Australia
Ashleigh
The price is ฿1,180
฿1,213 total
20 Jun - 21 Jun
DC Suites Aeropuerto

Grand Hotel Guayaquil, Centro Histórico.

Grand Hotel Guayaquil, Centro Histórico.
4.0 star property
7.9 km from Santa Maria
9.2 out of 10, Wonderful, (1,000 reviews)
"Great place to stay"
United States
Martha Lucia
The price is ฿2,308
฿2,588 total
21 Jun - 22 Jun
Grand Hotel Guayaquil, Centro Histórico.

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
5.5 km from Santa Maria
9.4 out of 10, Exceptional, (1,001 reviews)
"Great place"
Canada
Michael
The price is ฿3,279
฿3,689 total
11 Jul - 12 Jul
Holiday Inn Guayaquil Airport by IHG

Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil
3.5 star property
Kennedy, 4.9 km from Santa Maria
9.0 out of 10, Wonderful, (1,001 reviews)
"Great location!"
United States
Laura
The price is ฿2,623
฿2,935 total
26 Jun - 27 Jun
Courtyard by Marriott Guayaquil

Radisson Hotel Guayaquil

Radisson Hotel Guayaquil
5.0 star property
Kennedy, 4.9 km from Santa Maria
9.2 out of 10, Wonderful, (698 reviews)
"Good hotel"
United States
juan pablo
The price is ฿2,623
฿2,967 total
21 Jun - 22 Jun
Radisson Hotel Guayaquil

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana, 7.5 km from Santa Maria
9.2 out of 10, Wonderful, (1,001 reviews)
"Airport transfer and breakfast were great!"
United States
Halima
The price is ฿3,620
฿4,064 total
5 Jul - 6 Jul
Wyndham Guayaquil Puerto Santa Ana

Hotel Palace Guayaquil

Hotel Palace Guayaquil
4.0 star property
7.9 km from Santa Maria
9.2 out of 10, Wonderful, (937 reviews)
"Excellent service"
United States
Maritza
The price is ฿1,927
฿2,169 total
20 Jun - 21 Jun
Hotel Palace Guayaquil

Hotel GH Alexander

Hotel GH Alexander
3.5 star property
7.3 km from Santa Maria
8.6 out of 10, Excellent, (42 reviews)
"Great value hot water clean friendly staff on site restaurant "
United States
Monty
The price is ฿1,135
฿1,167 total
23 Jun - 24 Jun
Hotel GH Alexander

Luxva Hotel Boutique

Luxva Hotel Boutique
3.0 star property
Urdesa, 4.7 km from Santa Maria
9.4 out of 10, Exceptional, (181 reviews)
"Love the breakfast menu and security."
United States
Marcela
The price is ฿3,153
฿3,186 total
27 Jun - 28 Jun
Luxva Hotel Boutique

Suitesecu Rentals Guayaquil

Suitesecu Rentals Guayaquil
4.5 star property
Garzota, 5.1 km from Santa Maria
9.2 out of 10, Wonderful, (12 reviews)
"Friendly and very responsive staff. Clean and well apportioned suite"
Ecuador
Jacques
The price is ฿974
฿1,187 total
20 Jun - 21 Jun
Suitesecu Rentals Guayaquil

TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport
4.5 star property
Simón Bolívar, 4.9 km from Santa Maria
9.0 out of 10, Wonderful, (1,001 reviews)
"Great place to stay, connected to Large Mall with multiple food venue's"
United States
Francis
The price is ฿2,623
฿2,967 total
20 Jun - 21 Jun
TRYP by Wyndham Guayaquil Airport

Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels
4.0 star property
8 km from Santa Maria
9.2 out of 10, Wonderful, (1,002 reviews)
"Great location, very kind staff."
United States
Tomas
The price is ฿2,262
฿2,571 total
4 Jul - 5 Jul
Unipark by Oro Verde Hotels

Hotel Marcelius

Hotel Marcelius
3.5 star property
Kennedy, 4.7 km from Santa Maria
8.2 out of 10, Very good, (239 reviews)
"Very nice!"
United States
Michael
The price is ฿2,128
฿2,374 total
20 Jun - 21 Jun
Hotel Marcelius

Harmonie

Harmonie
2.0 star property
Simón Bolívar, 4.8 km from Santa Maria
9.0 out of 10, Wonderful, (104 reviews)
"Room was spotless, the staff was wonderful and helpful I can’t wait to visit again "
United States
Marco
The price is ฿984
฿984 total
20 Jul - 21 Jul
Harmonie

Casa Serena

Casa Serena
2.5 star property
Simón Bolívar, 4.9 km from Santa Maria
9.2 out of 10, Wonderful, (57 reviews)
"Nice room, close to the airport. Was a bit noise at night because of the street dogs"
Australia
pavel
The price is ฿943
฿943 total
27 Jun - 28 Jun
Casa Serena

Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil
4.0 star property
Downtown Guayaquil, 8.1 km from Santa Maria
9.4 out of 10, Exceptional, (311 reviews)
"Clean room and friendly environment. Well located in front of Malecón 2000"
Canada
Gonzalo
The price is ฿1,771
฿1,997 total
20 Jun - 21 Jun
Ibis Styles El Malecon Guayaquil

Hotel Patrimonial by Greenfield

Hotel Patrimonial by Greenfield
3.5 star property
Downtown Guayaquil, 7.5 km from Santa Maria
8.4 out of 10, Very good, (156 reviews)
"The pool was enjoyable but going during the day so the water isn’t as cold."
United States
Julio
The price is ฿1,453
฿1,486 total
20 Jun - 21 Jun
Hotel Patrimonial by Greenfield
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Maria

Find the best Santa Maria areas for the activities you enjoy most.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

Puerto Santa Ana

Restaurants and river views are some things travellers note about Puerto Santa Ana. Check out Santa Ana Hill or Artisan Market while you're familiarising yourself with the larger area.

Bolívar

While Bolívar may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Malecon Mall and Sports Federation of Guayas.

Garzota

The restaurants and shopping are a few reasons travellers visit Garzota. Though there aren't many top sights in the neighbourhood, you can visit Mall del Sol Shopping Center and City Mall, a few notable attractions nearby.

Top Santa Maria Hotel Reviews

Frequently asked questions

What is Santa Maria like?
Travellers are sure to enjoy a stay in Guayaquil's Santa Maria neighbourhood.
If I need to cancel my hotel reservation in Santa Maria, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best deals in Santa Maria.
What can I see and do in this Guayaquil neighbourhood?
Salón de Eventos Rubi, City Mall and Guayaquil Parrot are just a few of the places to visit in and around Santa Maria. La Rotonda Shopping Center and Santa Ana Port are also worth a visit when you're out sightseeing in Guayaquil.