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Our top choices for Santa Maria hotels

NP Hotel & Suites

NP Hotel & Suites
3.0 star property
5.6 km from Santa Maria
The price is ฿1,711
฿1,743 total
10 May - 11 May
NP Hotel & Suites

Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast
3.5 star property
3 km from Santa Maria
9.2 out of 10, Wonderful, (47 reviews)
"Swimming pool"
United States
Paulus
The price is ฿1,885
฿2,106 total
10 May - 11 May
Iguanazu Bed & Breakfast

Hotel La Ria Durán

Hotel La Ria Durán
3.0 star property
9.8 km from Santa Maria
7.4 out of 10, Good, (20 reviews)
"Muy buena experiencia"
Ecuador
HERNAN
The price is ฿1,547
฿1,547 total
8 May - 9 May
Hotel La Ria Durán

NCG Suite 5

NCG Suite 5
2.5 star property
4.3 km from Santa Maria
10.0 out of 10, Exceptional, (3 reviews)
"loved everything "
United States
Betty
The price is ฿1,128
฿1,128 total
22 May - 23 May
NCG Suite 5

NCG Suite Samanes 2

NCG Suite Samanes 2
3.0 star property
4.3 km from Santa Maria
8.8 out of 10, Excellent, (3 reviews)
"Propiedad segura, ordenada, limpia y tranquila."
Mexico
Shirley
The price is ฿1,044
฿1,076 total
8 May - 9 May
NCG Suite Samanes 2

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
5.5 km from Santa Maria
9.4 out of 10, Exceptional, (1,002 reviews)
"Excellent service, comfortable beds, quiet, and good meals. "
Australia
Gareth
The price is ฿3,158
฿3,554 total
24 May - 25 May
Holiday Inn Guayaquil Airport by IHG

NCG Suite 2

NCG Suite 2
3.0 star property
4.3 km from Santa Maria
10.0 out of 10, Exceptional, (5 reviews)
"Lugar muy tranquilo. Silencioso. Seguro. Buena cama, tele, cocina."
Switzerland
Anonymous traveller
The price is ฿1,044
฿1,076 total
14 May - 15 May
NCG Suite 2

Casa Veranda

Casa Veranda
2.5 star property
8.9 km from Santa Maria
The price is ฿1,015
฿1,015 total
8 May - 9 May
Casa Veranda

Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil
5.0 star property
Downtown Guayaquil, 8.1 km from Santa Maria
9.0 out of 10, Wonderful, (90 reviews)
"Excellent in every aspect. Friendly staff. Comfortable rooms. "
United States
Juan
The price is ฿2,164
฿2,541 total
30 May - 31 May
Doubletree By Hilton Guayaquil

DC Suites Aeropuerto

DC Suites Aeropuerto
3.0 star property
Simón Bolívar, 5.2 km from Santa Maria
9.0 out of 10, Wonderful, (624 reviews)
"Clean room and nice staff"
United States
JUAN BERNARDO
The price is ฿1,102
฿1,134 total
8 May - 9 May
DC Suites Aeropuerto

Hotel del Parque

Hotel del Parque
4.5 star property
7 km from Santa Maria
9.8 out of 10, Exceptional, (113 reviews)
"Breakfast excellent"
United States
Priscilla
The price is ฿13,823
฿15,206 total
14 May - 15 May
Hotel del Parque

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana, 7.5 km from Santa Maria
9.2 out of 10, Wonderful, (1,003 reviews)
"great safe place will be back "
United States
Tracy
The price is ฿3,538
฿3,972 total
5 Jun - 6 Jun
Wyndham Guayaquil Puerto Santa Ana

Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 7.8 km from Santa Maria
8.8 out of 10, Excellent, (138 reviews)
"Breakfast was good. I enjoyed my scrambled eggs and toast "
United States
Caitlin
The price is ฿1,808
฿2,021 total
3 Jun - 4 Jun
Mansión del Río

Guayacan Apart Hotel

Guayacan Apart Hotel
2.0 star property
Downtown Guayaquil, 7.6 km from Santa Maria
The price is ฿1,289
฿1,289 total
8 May - 9 May
Guayacan Apart Hotel

Hilton Colon Guayaquil

Hilton Colon Guayaquil
4.5 star property
Kennedy, 4.2 km from Santa Maria
8.6 out of 10, Excellent, (907 reviews)
"Overall experience would give it a 4.5 stars. Staff for the most part very friendly and helpful. Food was ok, clean rooms, exec lounge was nice to have! Would recommend!"
United States
Alex
The price is ฿3,150
฿3,545 total
24 May - 25 May
Hilton Colon Guayaquil

NCG Suite Samanes 3

NCG Suite Samanes 3
2.5 star property
4.2 km from Santa Maria
The price is ฿1,044
฿1,076 total
8 May - 9 May
NCG Suite Samanes 3

Hostal Macaw

Hostal Macaw
3.0 star property
Kennedy, 4.6 km from Santa Maria
10.0 out of 10, Exceptional, (9 reviews)
"Contento por haber reservado una noche de estadía en esta gran propiedad, desde la bienvenida, un ambiente cálido y cordial, la habitación cómoda, limpia y con A/C funcionando perfectamente, el desayuno vino incluido en la tarifa. La zona donde esta ubicada la hostal, muy segura y cerca de todo, accesible en uber y en una zona muy central para mis actividades. Volveré sin duda y tomare mas dias acá."
Ecuador
SANTIAGO
The price is ฿2,251
฿2,283 total
8 May - 9 May
Hostal Macaw

Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 6.9 km from Santa Maria
9.6 out of 10, Exceptional, (1,007 reviews)
"Room clean, airport shuttle a nice bonus"
Canada
LESLIE
The price is ฿2,546
฿2,881 total
17 May - 18 May
Oro Verde Guayaquil

Casa Serena

Casa Serena
2.5 star property
Simón Bolívar, 4.9 km from Santa Maria
9.2 out of 10, Wonderful, (54 reviews)
"the property was ok for the price"
United States
ASONG
The price is ฿870
฿870 total
6 Jun - 7 Jun
Casa Serena

Luxva Hotel Boutique

Luxva Hotel Boutique
3.0 star property
Urdesa, 4.7 km from Santa Maria
9.4 out of 10, Exceptional, (180 reviews)
"Clean room, staff, location"
United States
Veronica
The price is ฿2,755
฿2,787 total
9 May - 10 May
Luxva Hotel Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Maria

Find the best Santa Maria areas for the activities you enjoy most.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

Puerto Santa Ana

Restaurants and river views are some things travellers note about Puerto Santa Ana. Check out Santa Ana Hill or Numa Pompilio Llona Street while you're familiarising yourself with the larger area.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to World Trade Center or San Marino Mall.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Top Santa Maria Hotel Reviews

Frequently asked questions

What is Santa Maria like?
Travellers are sure to enjoy a stay in Guayaquil's Santa Maria neighbourhood.
If I need to cancel my hotel reservation in Santa Maria, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best deals in Santa Maria.
What can I see and do in this Guayaquil neighbourhood?
Salón de Eventos Rubi, City Mall and Guayaquil Parrot are just a few of the places to visit in and around Santa Maria. La Rotonda Shopping Center and Santa Ana Port are also worth a visit when you're out sightseeing in Guayaquil.