The Best Hotels in Guadalupe District, Santa Fe - 2026 Updated Prices

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Where to stay in Guadalupe District

Find the best Guadalupe District areas for the activities you enjoy most.

Downtown Santa Fe

Visitors to Downtown Santa Fe rave about its fascinating museums, popular shops and acclaimed art galleries. You might also want to make some time to see Santa Fe Plaza or Lensic Performing Arts Center while you're exploring the neighbourhood.

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Historic Eastside

While visiting Historic Eastside, you might make a stop by sights like Canyon Road and Nedra Matteucci Galleries.

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Southside

Southside is known for its popular shops, and with sights like Meow Wolf and International Museum of Collage, Assemblage & Construction, you won't get bored spending a day wandering around this part of Santa Fe.

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Cathedral Basilica of St. Francis of Assisi in Santa Fe, New Mexico

Northeast Santa Fe

While Northeast Santa Fe isn't home to many top sights, Santa Fe Plaza and New Mexico Museum of Art are some notable places to visit nearby.

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North Hills

While there might not be top attractions in North Hills, you can explore the larger area and discover places like Santa Fe Plaza and Canyon Road.

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Top Guadalupe District Hotel Reviews

Drury Plaza Hotel in Santa Fe

10/10 Excellent

"Breakfast was excellent!"

Hotel Glorieta

10/10 Excellent

"The amenities was not something I cared about using. I was vacation to see things. The was beyond wonderful. One day I face planted in Santa Fe and when I got back Sasha at the front desk saw it. She immediately got the first aid kit and an ice pack. The room was so great I extended my stay. The restaurant is amazing food!! Ask for Noah as your waiter"

Piñon Court By La Fonda

10/10 Excellent

"It was a comfortable and welcoming establishment. Location was excellent and within easy walking distance of the main attractions in Santa Fe. Breakfast was consistently well prepared with quality food. We found all staff cheerful, professional and ready to help. We had last minute unplanned travel changes which the hotel happily accommodated. Our first room was smaller than expected, the second larger, and we were pleased with kivas in each room. The A/C was appreciated on hot days. The facility had character and history with a walking trail close by the Santa Fe river."

Coyote South

10/10 Excellent

"The room was clean and relatively new. It was a nice, very quintessentially New Mexico hotel. A good divergence from big chains that feel everywhere and nowhere at once. Price is pretty cheap for Santa Fe but it didn't feel like a cheap hotel, yanno? Breakfast didn't wow me with its range of offerings but the burritos were pretty darn tasty, and being made fresh. Easy enough on-off from the highway, but the parking lot was maybe tight for a semi or long camp trailer. Overall, 5/5 stars from me."

Inn at Santa Fe, SureStay Collection by Best Western

8/10 Good

"Cute hotel. Great breakfast. Construction around the hotel made getting there and leaving slightly difficult, but not the hotel’s fault. The hotel is aged, but quaint. Front desk staff were very friendly. Didn’t use the pool, but the pool area is small, and the parking lot is small, but didn’t have a problem finding a parking while we were there. Overall a good little hotel to stay at while visiting Santa Fe."

Frequently asked questions

What's it like in Guadalupe District?

You'll be sure to have fun exploring Santa Fe's Guadalupe District neighbourhood. Make sure that you visit Santa Fe Railyard and Santa Fe Farmers Market as part of your Guadalupe District travel plans.

How many hotels are there in the Guadalupe District area?

If you're searching for places to stay in Santa Fe, Expedia has something to meet your needs with 66 Guadalupe District hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Guadalupe District, will I receive a refund?

Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to get the best options available in Guadalupe District.

What can I see and do in this Santa Fe neighbourhood?

Sights like TAI Modern, El Museo Cultural and Art Vault can be part of your cultural tour of Guadalupe District. As you're discovering the neighbourhood, Santa Fe Railyard and Santa Fe Farmers Market are some other places worth a visit. Santa Fe Plaza, SITE Santa Fe and Santuario De Nuestra Senora de Guadalupe are just a few of the places to visit in and around Guadalupe District. While you're out sightseeing, Harrell House of Natural Oddities and Bug Museum and Andrea Fisher Fine Pottery are a couple of additional sights to visit in Santa Fe.

How can I get around Guadalupe District and the greater Santa Fe area?

If you want to head out of town, you can hop aboard a train at Santa Fe Depot.

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Our top choices for Guadalupe District hotels

Guadalupe Inn

Inn at Santa Fe, SureStay Collection by Best Western

Cities Of Gold Casino

Coyote South

The Sage Hotel

La Quinta Inn by Wyndham Santa Fe

Quality Inn Santa Fe New Mexico

King's Rest Court Inn

Hotel Inn Santa Fe

Ramada by Wyndham Santa Fe

Econo Lodge Inn & Suites Santa Fe South

Baymont by Wyndham Santa Fe

Motel 6 Santa Fe

Hilton Santa Fe Buffalo Thunder

The Mystic Santa Fe

Comfort Inn Santa Fe South

Cottonwood Court Motel

Holiday Inn Express & Suites Santa Fe by IHG

Hampton Inn & Suites Los Alamos White Rock

Fairfield Inn & Suites by Marriott Santa Fe

Where to stay in Guadalupe District

Downtown Santa Fe

Historic Eastside

Southside

Northeast Santa Fe

North Hills

Top Guadalupe District Hotel Reviews

Drury Plaza Hotel in Santa Fe

Frequently asked questions

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