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Check prices for these dates

This weekend
25 Sep - 27 Sep
Next weekend
2 Oct - 4 Oct

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Our top choices for Grand Isle hotels

A beach with a clear sky and calm sea.

1. Pet Friendly Beach House - Lazy Palms

Pet Friendly Beach House - Lazy Palms
4.0 star property
Grand Isle
Pet Friendly Beach House - Lazy Palms
A wooden boardwalk leading to a beach with clear skies.

2. Driftwood Inn

Driftwood Inn
2.0 star property
0.5 km from Grand Isle
9.6 out of 10, Exceptional, (118 reviews)
"Great views and overall great place to stay"
United States
Stephen
The price is ฿7,986
฿8,944 total
includes taxes & fees
27 Sept - 28 Sept
Driftwood Inn
A wooden deck with a view of the ocean, a table with chairs, and a window with a view.

3. Beach House - Even Keel by PHG

Beach House - Even Keel by PHG
3.5 star property
0.3 km from Grand Isle
The price is ฿17,114
฿51,999 total
includes taxes & fees
9 Oct - 10 Oct
Beach House - Even Keel by PHG

4. Beach House - The Minty Pearl

Beach House - The Minty Pearl
3.0 star property
1.8 km from Grand Isle
Beach House - The Minty Pearl
A black double door entrance with a black mat, white walls, and two large green planters with flowers.

5. The Port Inn - Port St Joe, an Ascend Collection Hotel

The Port Inn - Port St Joe, an Ascend Collection Hotel
3.5 star property
Downtown Port St. Joe, 17.9 km from Grand Isle
9.0 out of 10, Wonderful, (474 reviews)
"The rooms were very clean. The bed was very soft. We enjoyed our complementary breakfast as well."
United States
Woody
The price is ฿5,265
฿5,897 total
includes taxes & fees
30 Sept - 1 Oct
The Port Inn - Port St Joe, an Ascend Collection Hotel
A hotel corridor with numbered doors, wicker chairs, and a doormat with text.

6. The Blu - A Boutique Motel

The Blu - A Boutique Motel
5.5 km from Grand Isle
The price is ฿1,546
฿3,355 total
includes taxes & fees
21 Oct - 22 Oct
The Blu - A Boutique Motel
A breakfast bar with seating, a refrigerator stocked with food, and a sign indicating breakfast service.

7. MainStay Suites Port Saint Joe South

MainStay Suites Port Saint Joe South
2.5 star property
22.1 km from Grand Isle
8.6 out of 10, Excellent, (775 reviews)
"Great location to many attractions great staff and room"
United States
Darryl
The price is ฿4,063
฿4,550 total
includes taxes & fees
25 Oct - 26 Oct
MainStay Suites Port Saint Joe South
A beach with driftwood and sparse vegetation along the shoreline.

8. The Pink Flamingo Boutique Motel

The Pink Flamingo Boutique Motel
3.0 star property
13.1 km from Grand Isle
9.0 out of 10, Wonderful, (8 reviews)
"Everything was great. BED WAS AMAZING."
United States
Pamela
The price is ฿5,763
฿8,272 total
includes taxes & fees
27 Sept - 28 Sept
The Pink Flamingo Boutique Motel
A hotel room with two beds, wooden headboards, a nightstand, a lamp, and a beach-themed wall mural.

9. Days Inn by Wyndham Panama City/Callaway

Days Inn by Wyndham Panama City/Callaway
2.0 star property
29.4 km from Grand Isle
6.8 out of 10, (569 reviews)
"The worst ever, video staff such rudes, not even have coffee for breakfast, ac much louder and noise. Terrible place"
United States
Ricardo
The price is ฿1,971
฿2,130 total
includes taxes & fees
30 Sept - 1 Oct
Days Inn by Wyndham Panama City/Callaway

10. Beach House - Turtle Tracks by PHG

Beach House - Turtle Tracks by PHG
4.0 star property
6.4 km from Grand Isle
Beach House - Turtle Tracks by PHG
A commercial area with various storefronts, including a boutique and a restaurant.

11. The Blu Boutique Motel

The Blu Boutique Motel
5.5 km from Grand Isle
The price is ฿5,664
฿8,495 total
includes taxes & fees
28 Sept - 29 Sept
The Blu Boutique Motel
A wooden staircase leading to a beach with waves and a sunset in the background.

12. Cape San Blas Inn

Cape San Blas Inn
3.0 star property
27 km from Grand Isle
9.8 out of 10, Exceptional, (82 reviews)
"I loved the back deck with a hot tub to look at the stars, as well as paddleboards, kayaks, and bicycles for use."
United States
Brittany
The price is ฿9,941
฿11,134 total
includes taxes & fees
28 Sept - 29 Sept
Cape San Blas Inn
A hotel room with a large bathtub, a sofa, a small table, a bed, and a large mirror.

13. Comfort Suites

Comfort Suites
2.5 star property
29 km from Grand Isle
8.6 out of 10, Excellent, (823 reviews)
"place was clean and safe. Bed was good and breakfast was hot."
United States
Sandra
The price is ฿2,506
฿2,708 total
includes taxes & fees
30 Sept - 1 Oct
Comfort Suites
A coastal residential area with a row of houses, a beach in the background, and a clear sky.

14. Sunset Shores Modern Oasis by the Sea

Sunset Shores Modern Oasis by the Sea
2.0 star property
11.3 km from Grand Isle
The price is ฿9,355
฿25,963 total
includes taxes & fees
8 Oct - 9 Oct
Sunset Shores Modern Oasis by the Sea
An aerial view of a resort with a swimming pool, a beach, and a road leading to the ocean.

15. Pet Friendly Beach House - Salt Therapy

Pet Friendly Beach House - Salt Therapy
3.5 star property
11.7 km from Grand Isle
The price is ฿9,526
฿39,083 total
includes taxes & fees
9 Oct - 10 Oct
Pet Friendly Beach House - Salt Therapy
A hotel sign for Candlewood Suites, an IHG hotel, with a parking lot and cars in front.

16. Candlewood Suites Panama City Tyndall AFB by IHG

Candlewood Suites Panama City Tyndall AFB by IHG
2.5 star property
28.6 km from Grand Isle
9.4 out of 10, Exceptional, (106 reviews)
"Clean hotel."
United States
Patricia
The price is ฿4,074
฿4,402 total
includes taxes & fees
5 Oct - 6 Oct
Candlewood Suites Panama City Tyndall AFB by IHG
A Holiday Inn Express & Suites hotel with a covered entrance, palm trees, and a parking lot.

17. Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
2.5 star property
29.1 km from Grand Isle
8.6 out of 10, Excellent, (529 reviews)
"We had a wonderful stay at this hotel for one night. The room was clean, comfortable, and well maintained, and everything we needed was available. The staff was friendly and welcoming, and the overall atmosphere was pleasant and relaxing. It was a great place for a short stay, and we would definitely consider staying here again. Highly recommended!"
United States
Mafiq
The price is ฿2,908
฿3,143 total
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
A coastal resort with multiple buildings, a swimming pool, and a beach area.

18. Cape Cottages by Panhandle Getaways

Cape Cottages by Panhandle Getaways
3.5 star property
22.8 km from Grand Isle
10.0 out of 10, Exceptional, (6 reviews)
"Brand new, quaint spot with really comfortable beds. "
United States
Anonymous traveller
The price is ฿5,615
฿19,879 total
includes taxes & fees
8 Oct - 9 Oct
Cape Cottages by Panhandle Getaways
A wooden deck with white chairs and a glass door, overlooking a beach.

19. Beachfront House - Casa Bella Del Sol

Beachfront House - Casa Bella Del Sol
4.0 star property
26.6 km from Grand Isle
The price is ฿21,125
฿54,132 total
includes taxes & fees
16 Oct - 17 Oct
Beachfront House - Casa Bella Del Sol
A hotel room with two beds, wooden flooring, and a window with blinds.

20. Extended Stay America Select Suites - Panama City - Callaway

Extended Stay America Select Suites - Panama City - Callaway
2.5 star property
30.1 km from Grand Isle
6.2 out of 10, (546 reviews)
"Super easy to check in and really clean"
United States
jose j
The price is ฿2,146
฿2,319 total
includes taxes & fees
28 Sept - 29 Sept
Extended Stay America Select Suites - Panama City - Callaway
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Grand Isle

Find the best Grand Isle areas for the activities you enjoy most.
A marina at sunset with boats docked and a wooden pier.
Photo by Russell Hewatt
Open Photo by Russell Hewatt

Downtown Port St. Joe

If you're spending some time in Downtown Port St. Joe, Port Saint Joe City Hall and Constitution Convention Museum State Park are top sights worth seeing.

A white house with a black roof, a white lighthouse with a black top, and a calm lake with purple flowers in the foreground.

Cape Breezes

Cape Breezes might not have many top sights, but T.H. Stone Memorial St. Joseph Peninsula State Park and St. Joseph Peninsula State Park are two attractions nearby that you can check out.

A beach with driftwood formations at sunset.

Gulf Aire

While Gulf Aire may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Saint Joe Beach and Mexico Beach.

A sandy beach with calm waters and a large cloud in the sky.

Waterside Village

While Waterside Village isn't home to many top sights, Mexico Beach Marina and Mexico Beach are some notable places to visit nearby.

A coastal landscape with tall grasses, a palm tree, and a sunset over the water.

Palms

While there might not be top attractions in Palms, you can explore the larger area and discover places like Mexico Beach and Mexico Beach Marina.

Top Grand Isle Hotel Reviews

Driftwood Inn

Driftwood Inn

10/10 Excellent
"We loved this hotel. The room was well kept and clean. The grounds were lovely. The staff treated you like family. Can’t wait to go back!"
Ginger 3-night trip
Posted 4 days ago
Driftwood Inn

Frequently asked questions

What is Grand Isle like?
Travellers to Mexico Beach's Grand Isle neighbourhood will be sure to enjoy a stay here.
How many hotels are there in Grand Isle?
When you want to put your feet up after a day of exploring the sights in Mexico Beach, you can choose from 11 Expedia hotels and other accommodation options in Grand Isle.
If I need to cancel my hotel reservation in Grand Isle, will I receive a refund?
Yes! The majority of room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view the best options available in Grand Isle.
What is there to do around this Mexico Beach neighbourhood?
Mexico Beach Business Center, Mexico Beach and Mexico Beach Marina are just a few of the places to visit in and around Grand Isle. When you're sightseeing around the area, Saint Joe Beach and Windmark Beach are a couple of other sights to visit.