What is Grand Isle like?

Travellers to Mexico Beach's Grand Isle neighbourhood will be sure to enjoy a stay here.

How many hotels are there in Grand Isle?

When you want to put your feet up after a day of exploring the sights in Mexico Beach, you can choose from 11 Expedia hotels and other accommodation options in Grand Isle.

If I need to cancel my hotel reservation in Grand Isle, will I receive a refund?

Yes! The majority of room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view the best options available in Grand Isle.

What is there to do around this Mexico Beach neighbourhood?

Mexico Beach Business Center, Mexico Beach and Mexico Beach Marina are just a few of the places to visit in and around Grand Isle. When you're sightseeing around the area, Saint Joe Beach and Windmark Beach are a couple of other sights to visit.

The Best Hotels in Grand Isle, Port St. Joe - 2026 Updated Prices

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Our top choices for Grand Isle hotels

1. Mexico Beach Retreat w/ Grill & Private Pool!

Grand Isle

฿25,265 total

includes taxes & fees

11 Jul - 12 Jul

2. MainStay Suites Port Saint Joe South

22.1 km from Grand Isle

Austin

฿6,667 total

includes taxes & fees

6 Jul - 7 Jul

3. Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

29.1 km from Grand Isle

Megan

฿4,710 total

includes taxes & fees

19 Jul - 20 Jul

4. Driftwood Inn

0.5 km from Grand Isle

Jana

฿10,382 total

includes taxes & fees

6 Jul - 7 Jul

5. The Port Inn - Port St Joe, an Ascend Collection Hotel

Downtown Port St. Joe, 17.9 km from Grand Isle

Leanne

฿8,031 total

includes taxes & fees

12 Jul - 13 Jul

Desk, blackout curtains, iron/ironing board, free cots/infant beds

6. Comfort Suites

29 km from Grand Isle

Susan

฿3,779 total

includes taxes & fees

30 Jun - 1 Jul

Laptop workspace, iron/ironing board, free cots/infant beds, free WiFi

7. Days Inn by Wyndham Panama City/Callaway

29.4 km from Grand Isle

jose j

฿2,422 total

includes taxes & fees

12 Jul - 13 Jul

Desk, laptop workspace, iron/ironing board, free WiFi

8. Extended Stay America Select Suites - Panama City - Callaway

30.1 km from Grand Isle

jose j

฿2,921 total

includes taxes & fees

29 Jun - 30 Jun

Sun-loungers, beach towels, rowing, fishing

9. Cape San Blas Inn

27 km from Grand Isle

Tonianne

฿11,080 total

includes taxes & fees

29 Jun - 30 Jun

10. Candlewood Suites Panama City Tyndall AFB by IHG

28.6 km from Grand Isle

Chris

฿5,058 total

includes taxes & fees

7 Jul - 8 Jul

11. The Pink Flamingo Boutique Motel

13.1 km from Grand Isle

Suzette

฿9,856 total

includes taxes & fees

2 Jul - 3 Jul

12. Walk to Shore: 'oyster House' Port St Joe Getaway

11.5 km from Grand Isle

Kimberly

฿22,448 total

includes taxes & fees

27 Jun - 28 Jun

House, Resort View | Private kitchen | Full-sized fridge, microwave, oven, stovetop

13. Beach House - Coastal Dreaming

6.4 km from Grand Isle

Jennifer

฿27,206 total

includes taxes & fees

16 Jul - 17 Jul

14. Cape Cottages by Panhandle Getaways

22.8 km from Grand Isle

Anonymous traveller

฿23,700 total

includes taxes & fees

9 Jul - 10 Jul

15. Beach House - Salty Dolphin

22.3 km from Grand Isle

฿34,774 total

includes taxes & fees

25 Jun - 26 Jun

16. Beach House - Sun of a Beach

8.8 km from Grand Isle

฿39,019 total

includes taxes & fees

27 Jun - 28 Jun

17. Beach House - Even Keel by PHG

0.3 km from Grand Isle

Condo, Ocean View | Living area | 42-inch Smart TV with digital channels, Netflix, Hulu

18. Mexico Beach - Summerhouse by PHG

0.5 km from Grand Isle

฿28,240 total

includes taxes & fees

25 Jun - 26 Jun

19. Luxe Beachfront Windmark Cottage w/ Deck!

12.4 km from Grand Isle

Andrea

฿16,935 total

includes taxes & fees

11 Jul - 12 Jul

20. Stroll to Shore: Airy Home w/ Lanai in Port St Joe

12.4 km from Grand Isle

View all properties

Where to stay in Grand Isle

Find the best Grand Isle areas for the activities you enjoy most.

Downtown Port St. Joe

If you're spending some time in Downtown Port St. Joe, Constitution Convention Museum State Park and Centennial Building are top sights worth seeing.

See properties

Cape Breezes

Cape Breezes might not have many top sights, but T.H. Stone Memorial St. Joseph Peninsula State Park and St. Joseph Peninsula State Park are two attractions nearby that you can check out.

See properties

Beach Sunset Through the Stumps at Cape San Blas, Florida

Gulf Aire

While Gulf Aire may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Saint Joe Beach and Mexico Beach.

See properties

Waterside Village

While Waterside Village isn't home to many top sights, Mexico Beach Marina and Mexico Beach are some notable places to visit nearby.

See properties

Palms

While there might not be top attractions in Palms, you can explore the larger area and discover places like Mexico Beach and Mexico Beach Marina.

See properties

Top Grand Isle Hotel Reviews

Cape San Blas Inn

10/10 Excellent

"I loved the back deck with a hot tub to look at the stars, as well as paddleboards, kayaks, and bicycles for use."

Driftwood Inn

10/10 Excellent

"The front staff was amazing! From arriving early and being able to check in right away was just the cherry on top after a lengthy drive. After the first night of freezing in the room, I was able to run downstairs and Tristan (GM) hooked me up with allll the blankets AND towels since housekeeping was a bit confusing. We loved having the perfect ocean view. I watched the sun rise every morning there. Direct beach access is a dream when all you want is to park and not leave - Driftwood met that expectation! Everything was clean. The elevator was fast (IYKYK). Loved having access to a huge ice machine, cheap laundry services and the cutest gift shop. We didn’t get a chance to just sit and swing on the porch but it was adorable. They have a nice shower off post beach right before the ramp which made going to the rooms nice, clean and easy. We ate at Shipwreck (recommended by one of the front desk ladies) and it was good. Lots of little shops around. I’m already planning my next trip but this time with a stove. IF I had to make any con it would be that if you were on the end or next to an end room your balconies are not as private - you’ll be able to say hi to your neighbor. Overall, 10/10. Highly recommended!! ⭐️⭐️⭐️⭐️⭐️"

Candlewood Suites Panama City Tyndall AFB by IHG

10/10 Excellent

"Thank goodness for pet friendly but I think the price for a little dog 12 pounds Chihuahua mixed it was $100. I think that was kind of steep and I could see it. It was if it was for a big dog, but it is what it is I will be staying there again. It’s nice brand new one year old."

Search Hotels in Grand Isle, Port St. Joe

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Our top choices for Grand Isle hotels

1. Mexico Beach Retreat w/ Grill & Private Pool!

2. MainStay Suites Port Saint Joe South

3. Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

4. Driftwood Inn

5. The Port Inn - Port St Joe, an Ascend Collection Hotel

6. Comfort Suites

7. Days Inn by Wyndham Panama City/Callaway

8. Extended Stay America Select Suites - Panama City - Callaway

9. Cape San Blas Inn

10. Candlewood Suites Panama City Tyndall AFB by IHG

11. The Pink Flamingo Boutique Motel

12. Walk to Shore: 'oyster House' Port St Joe Getaway

13. Beach House - Coastal Dreaming

14. Cape Cottages by Panhandle Getaways

15. Beach House - Salty Dolphin

16. Beach House - Sun of a Beach

17. Beach House - Even Keel by PHG

18. Mexico Beach - Summerhouse by PHG

19. Luxe Beachfront Windmark Cottage w/ Deck!

20. Stroll to Shore: Airy Home w/ Lanai in Port St Joe

Where to stay in Grand Isle

Downtown Port St. Joe

Cape Breezes

Gulf Aire

Waterside Village

Palms

Top Grand Isle Hotel Reviews

Cape San Blas Inn

Frequently asked questions

Explore a world of travel with Expedia