Search Hotels Near Florida Keys National Marine Sanctuary, Key West

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Florida Keys National Marine Sanctuary hotels

Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
3.5 star property
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
10.0 out of 10, Exceptional, (1,015 reviews)
"Great staff, breakfast and happy hour. "
United States
Tina
The price is ฿8,465
฿9,523 total
includes taxes & fees
8 Jun - 9 Jun
Almond Tree Inn Hotel - Adults Only

Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,007 reviews)
"This is an amazing place ! If you are coming to Key West you won’t find a nicer place. "
United States
Vicki
The price is ฿8,187
฿9,210 total
includes taxes & fees
8 Jun - 9 Jun
Orchid Key Inn - Adults Only

The Gardens Hotel

The Gardens Hotel
4.0 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,004 reviews)
"Hands down the nicest rental my wife and I have ever stayed at. The proximity to every spot you want to be is amazing, the breakfast was perfect, and the staff went above and beyond after I made a stupid booking mistake."
United States
Salvatore
The price is ฿8,540
฿9,608 total
includes taxes & fees
10 Jun - 11 Jun
The Gardens Hotel

Key West Villas

Key West Villas
3.5 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (261 reviews)
"This was the best place we have stayed at in Key West! It was super quiet but only a block from Duval. The owners really put a lot of care into the place and are super nice! Definitely would stay there again! "
United States
Jennifer
The price is ฿7,317
฿8,232 total
includes taxes & fees
19 May - 20 May
Key West Villas

Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages
2.5 star property
Historic Seaport, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (955 reviews)
"Defiantly would stay again and so close to everything"
United States
kelly
The price is ฿9,436
฿10,615 total
includes taxes & fees
2 Jun - 3 Jun
Simonton Court Historic Inn & Cottages

The Marquesa Hotel

The Marquesa Hotel
3.5 star property
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,005 reviews)
"Great accommodations and great staff"
United States
Julian
The price is ฿9,436
฿12,452 total
includes taxes & fees
16 Jun - 17 Jun
The Marquesa Hotel

The Conch House Heritage Inn

The Conch House Heritage Inn
3.5 star property
Old Town Key West, 1.1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (174 reviews)
"Great location "
United Kingdom
Lucy
The price is ฿8,149
฿9,168 total
includes taxes & fees
1 Jun - 2 Jun
The Conch House Heritage Inn

Douglas House - Adults Only

Douglas House - Adults Only
3.0 star property
Uptown - Upper Duval, 0.9 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (387 reviews)
"Great location, helpful staff and fun people. Would stay here again…the pool and room were fantastic"
United States
Scott
The price is ฿5,854
฿7,245 total
includes taxes & fees
2 Jun - 3 Jun
Douglas House - Adults Only

Tropical Inn

Tropical Inn
3.5 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (403 reviews)
"Very friendly staff and a prime location."
United States
Akhenaton
The price is ฿6,511
฿8,141 total
includes taxes & fees
21 May - 22 May
Tropical Inn

Weatherstation Inn

Weatherstation Inn
2.5 star property
Truman Annex, 0.6 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,001 reviews)
"Perfect stay!"
United States
A. Elise
The price is ฿6,497
฿7,310 total
includes taxes & fees
19 May - 20 May
Weatherstation Inn

Coco Plum Inn

Coco Plum Inn
3.0 star property
Downtown Key West, 0.6 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (531 reviews)
"Loved the property and staff was super friendly."
United States
Brinkley
The price is ฿8,923
฿10,039 total
includes taxes & fees
21 May - 22 May
Coco Plum Inn

L'Habitation Guest House

L'Habitation Guest House
2.5 star property
Historic Seaport, 0.8 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (981 reviews)
"This was a lovely well stocked, and comfortable stay."
United States
Pat
The price is ฿4,768
฿5,363 total
includes taxes & fees
26 May - 27 May
L'Habitation Guest House

Island City House Hotel

Island City House Hotel
3.0 star property
Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,001 reviews)
"Nice location "
United States
Michael
The price is ฿8,103
฿9,116 total
includes taxes & fees
16 Jun - 17 Jun
Island City House Hotel

Duval House

Duval House
3.0 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,043 reviews)
"Nice place clean, good breakfast right on Duval for easy walk to everything "
Canada
Parmjit
The price is ฿6,497
฿8,012 total
includes taxes & fees
8 Jun - 9 Jun
Duval House

Santa Maria Suites

Santa Maria Suites
4.0 star property
Uptown - Upper Duval, 1.3 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,007 reviews)
"Great hotel and room. Very clean, great location."
United States
Cindy
The price is ฿10,089
฿13,554 total
includes taxes & fees
27 May - 28 May
Santa Maria Suites

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
3.5 star property
Old Town Key West, 1.7 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (144 reviews)
"The staff and other guests were very friendly. The room was spacious and the bed was comfortable. "
United States
Annette
The price is ฿5,554
฿7,547 total
includes taxes & fees
19 May - 20 May
Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Ella's Cottages - Key West Historic Inns

Ella's Cottages - Key West Historic Inns
3.5 star property
Old Town Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (475 reviews)
"Cute place. Great location to everything on Duval. Service was great and friendly."
United States
DJS Darren Jay
The price is ฿6,729
฿9,223 total
includes taxes & fees
25 May - 26 May
Ella's Cottages - Key West Historic Inns

Ambrosia Key West

Ambrosia Key West
3.5 star property
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,000 reviews)
"Breakfast by the pool was excellent! Pools were nice, with plenty of areas for privacy. We especially enjoyed the private patios and courtyards. Fantastic location!"
United States
Tina
The price is ฿6,951
฿7,820 total
includes taxes & fees
19 May - 20 May
Ambrosia Key West

The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West, 1.6 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,002 reviews)
"This is a great place to stay, quiet and nice accommodations. Awesome little courtyard for breakfast."
United States
Jacqueline
The price is ฿5,898
฿7,452 total
includes taxes & fees
21 May - 22 May
The Grand Guesthouse

Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
4.0 star property
Uptown - Upper Duval, 1.2 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,001 reviews)
"Fresh continental breakfast, clean room, close to everything."
United States
BOBBY J.
The price is ฿6,243
฿11,155 total
includes taxes & fees
31 May - 1 Jun
Southernmost House - Adult Exclusive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Florida Keys National Marine Sanctuary

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Queen Deluxe ADA | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds
Almond Tree Inn Hotel - Adults Only
3.5 star property
10.0
Exceptional
1,015 reviews
View
Property grounds
Orchid Key Inn - Adults Only
3.5 star property
9.8
Exceptional
1,007 reviews
View
Exterior detail
The Gardens Hotel
4.0 star property
9.8
Exceptional
1,004 reviews
View
Front of property
Key West Villas
3.5 star property
9.8
Exceptional
261 reviews
View
Queen with Pool View | Minibar, in-room safe, individually decorated, individually furnished
Simonton Court Historic Inn & Cottages
2.5 star property
9.8
Exceptional
955 reviews
View

Top Florida Keys National Marine Sanctuary Hotel Reviews

Hotels near other Florida Keys National Marine Sanctuary attractions

Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?
Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, cycling and lively festivals. If you're looking for a convenient place to stay, take a look at the 1554 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Florida Keys National Marine Sanctuary?
Southernmost Beach Resort and Guesthouses is one of the top choices for your stay based on our traveller data, and this hotel offers 3 outdoor pools and a full-service spa. It's located just a short 0.7 mi (1.1 km) from Florida Keys National Marine Sanctuary. Other good choices close by include La Concha Key West, Autograph Collection and Opal Key Resort & Marina, Key West.
How many hotels will I find near Florida Keys National Marine Sanctuary?
Expedia has 1554 hotels and other accommodation options within a mile from Florida Keys National Marine Sanctuary.
If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best deals near Florida Keys National Marine Sanctuary.
What can I see and do near Florida Keys National Marine Sanctuary?
Florida Keys Eco - Discovery Center, Harry S. Truman Little White House and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum and Audubon House and Tropical Gardens are some of the notable landmarks to see in the area. You can watch performances at Waterfront Playhouse, Key West Film Society and Red Barn Theater if you're interested in local theatre.