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Check prices for these dates

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20 Dec - 21 Dec
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21 Dec - 22 Dec
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26 Dec - 28 Dec
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2 Jan - 4 Jan

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Our top choices for Epipoli hotels

Double Room, Private Bathroom | Desk, laptop workspace, free WiFi, bed sheets
B&B Kosmos

B&B Kosmos

B&B Kosmos
3.0 star property
Epipoli
9.6 out of 10, Exceptional, (72)
"We have traveled far and often and the host at Kosmos was the best that we ever met. He really surpassed the rest in every way imaginable. We strongly recommend anyone going to Syracuse in Sicily to stay at Kosmos. "
Canada
Binh
The price is ฿3,009
฿3,430 total
includes taxes & fees
3 Jan - 4 Jan 2026
B&B Kosmos
Seasonal outdoor pool
Hotel Relax

Hotel Relax

Hotel Relax
4.0 star property
Epipoli
8.2 out of 10, Very good, (33)
"Camera spaziosa e pulita, dintorni silenziosi, personale molto attento agli ospiti, gentile e cordiale, colazione a buffet con molte opzioni abbondanti, puntuali."
Italy
Gabriella
The price is ฿3,009
฿3,430 total
includes taxes & fees
9 Jan - 10 Jan 2026
Hotel Relax
Rooftop terrace
Caportigia Boutique Hotel

Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia, 3.7 km from Epipoli
9.4 out of 10, Exceptional, (257)
"Fine quality hotel with exceptional service. "
United States
Peter
The price is ฿4,179
฿4,965 total
includes taxes & fees
21 Dec - 22 Dec
Caportigia Boutique Hotel
Front of property – evening/night
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
4.0 star property
Ortigia, 4.6 km from Epipoli
9.6 out of 10, Exceptional, (908)
"The breakfast was delicious, the staff impeccable and the room delightful. All in all an excellent stay which I would wholeheartedly recommend. "
United Kingdom
Sarah
Algila' Ortigia Charme Hotel
Daily buffet breakfast (EUR 8 per person)
Dimore delle Zagare Ortigia

Dimore delle Zagare Ortigia

Dimore delle Zagare Ortigia
Ortigia, 4.7 km from Epipoli
9.8 out of 10, Exceptional, (160)
"It was a perfect location"
United States
Susan
Dimore delle Zagare Ortigia
Terrace/patio
Thalya Luxury Rooms

Thalya Luxury Rooms

Thalya Luxury Rooms
3.0 star property
3.4 km from Epipoli
9.0 out of 10, Wonderful, (42)
"Wonderful stay!"
United States
Kristie
Thalya Luxury Rooms
Terrace/patio
Grand Hotel Villa Politi

Grand Hotel Villa Politi

Grand Hotel Villa Politi
4.0 star property
Grottasanta, 3.7 km from Epipoli
8.6 out of 10, Excellent, (943)
"Wonderful hotel, nice area and great buffet breakfast"
United States
paula
The price is ฿3,457
฿3,941 total
includes taxes & fees
21 Dec - 22 Dec
Grand Hotel Villa Politi
Exterior
Il Giardino di Pietra

Il Giardino di Pietra

Il Giardino di Pietra
3.0 star property
27 km from Epipoli
8.8 out of 10, Excellent, (23)
"Good b&b, delivered the need for one night. A good choice in case I stop by in Noto another time "
United States
Claudio
Il Giardino di Pietra
Exterior
Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
5.0 star property
Ortigia, 4.1 km from Epipoli
9.4 out of 10, Exceptional, (252)
"Great location and very friendly staff"
United States
James
The price is ฿6,927
฿7,988 total
includes taxes & fees
14 Jan - 15 Jan 2026
Ortea Palace Hotel, Sicily, Autograph Collection
Superior Suite, Jetted Tub | Bathroom | Shower, designer toiletries, hair dryer, slippers
CinqueSuites Ortigia

CinqueSuites Ortigia

CinqueSuites Ortigia
Ortigia, 4.8 km from Epipoli
9.2 out of 10, Wonderful, (123)
"Great location for exploring the town. Good size room, had everything we need. Would recommend. "
Canada
Adrian
The price is ฿2,848
฿3,616 total
includes taxes & fees
1 Jan - 2 Jan 2026
CinqueSuites Ortigia
Exterior
Palazzo Salomone

Palazzo Salomone

Palazzo Salomone
3.0 star property
Ortigia, 5 km from Epipoli
9.2 out of 10, Wonderful, (19)
"Very nice hotel. "
Canada
Mark
The price is ฿3,310
฿3,773 total
includes taxes & fees
21 Dec - 22 Dec
Palazzo Salomone
Breakfast area
Giuggiulena Villa

Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia, 3.9 km from Epipoli
10.0 out of 10, Exceptional, (126)
"Fantastic stay. Made to feel very welcome and what a lovely relaxing place to stay. Evening meal was exceptional. "
United States
Paul
The price is ฿6,861
฿7,821 total
includes taxes & fees
4 Jan - 5 Jan 2026
Giuggiulena Villa
Terrace/patio
Alla Giudecca

Alla Giudecca

Alla Giudecca
3.0 star property
Ortigia, 4.9 km from Epipoli
8.4 out of 10, Very good, (273)
"We loved the history of the building, it was beautiful. Spacious rooms with outside sitting area. Walkable to all areas of interest in Ortigia and cafes and restaurants. Staff were helpful. "
United Kingdom
Carol
Alla Giudecca
Premium bedding, minibar, in-room safe, desk
Room 55

Room 55

Room 55
27.3 km from Epipoli
9.8 out of 10, Exceptional, (66)
"Room was splendid! Had a wonderful time exploring. Would stay again!"
Canada
rita
The price is ฿3,009
฿3,531 total
includes taxes & fees
3 Jan - 4 Jan 2026
Room 55
Junior Suite, Jetted Tub | Jetted bathtub
Hotel Flora

Hotel Flora

Hotel Flora
3.0 star property
27.3 km from Epipoli
8.8 out of 10, Excellent, (188)
"Very recommendable place. Enjoyed our stay"
Denmark
Thomas
Hotel Flora
Terrace/patio
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
5.0 star property
Ortigia, 4.3 km from Epipoli
9.0 out of 10, Wonderful, (571)
"Great stay!"
United States
Liza
The price is ฿6,229
฿7,219 total
includes taxes & fees
7 Jan - 8 Jan 2026
Grand Hotel Ortigia Siracusa
2 restaurants, breakfast, lunch, dinner served; Fusion cuisine
UNA HOTELS One Siracusa

UNA HOTELS One Siracusa

UNA HOTELS One Siracusa
4.0 star property
Grottasanta, 3.6 km from Epipoli
8.6 out of 10, Excellent, (540)
"Very nice hotel, nice sized rooms, great staff that was very helpful."
United States
Mark
The price is ฿4,323
฿4,928 total
includes taxes & fees
21 Dec - 22 Dec
UNA HOTELS One Siracusa
Sun deck
Oasi Del Gabbiano

Oasi Del Gabbiano

Oasi Del Gabbiano
5.9 km from Epipoli
9.6 out of 10, Exceptional, (28)
"A true slice of Italy - lovely kindly family hotel"
United Kingdom
Alison
Oasi Del Gabbiano
Rooftop terrace
Lanterne Magiche Ortigia

Lanterne Magiche Ortigia

Lanterne Magiche Ortigia
Ortigia, 4.9 km from Epipoli
9.4 out of 10, Exceptional, (183)
"Staff was wonderful, breakfast was superior."
United States
Joyce
Lanterne Magiche Ortigia
Lobby
B&B Ninfeo Siracusa

B&B Ninfeo Siracusa

B&B Ninfeo Siracusa
3.5 km from Epipoli
9.4 out of 10, Exceptional, (33)
"Very good B&B, clean, located near the centre. Very friendly staff!"
United Kingdom
Oksana
The price is ฿2,528
฿3,453 total
includes taxes & fees
7 Jan - 8 Jan 2026
B&B Ninfeo Siracusa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Epipoli

Find the best Epipoli areas for the activities you enjoy most.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.

Syracuse which includes street scenes as well as an individual female

Santa Lucia

Santa Lucia is noteworthy for its historical sites, and you can make a stop at top attractions like Porto Piccolo and Ionian Sea.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Top Epipoli Hotel Reviews

Grand Hotel Villa Politi

Grand Hotel Villa Politi

10/10 Excellent
"Great old “grand hotel”. Beautiful property. "
Steven 1-night trip
Posted 2 months ago
Grand Hotel Villa Politi

Frequently asked questions

What is Epipoli like?
Travellers to the Epipoli neighbourhood in Syracuse will be sure to enjoy their stay.
What's a favourite place to stay in Epipoli?
Based on Expedia customer reviews, B&B Kosmos is the highest ranked property in Epipoli. This B&B offers free breakfast and private balconies. Another top choice in the area is Hotel Relax.
How many hotels are there in the Epipoli area?
When you want to find places to stay in Syracuse, start by booking one of Expedia's 8 hotels and other accommodation options in Epipoli.
If I need to cancel my hotel reservation in Epipoli, will I receive a refund?
Yes, you'll find most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals in Epipoli.
What can I see and do in this Syracuse neighbourhood?
A few places to visit in the area around Epipoli include Cantine Pupillo, Greek Theatre of Syracuse and Latomia del Paradiso. Rope-makers' Cave and Ear of Dionysius are also worth a visit when you're out sightseeing in Syracuse.

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