An ancient amphitheater with stone seating and a small tower.

Search Hotels in Epipoli, Syracuse

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
25 Sep - 27 Sep
Next weekend
2 Oct - 4 Oct

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Epipoli hotels

A bedroom with a bed, a desk, a chair, a wardrobe, and a large window with curtains.

1. B&B Kosmos

B&B Kosmos
3.0 star property
Epipoli
9.6 out of 10, Exceptional, (78 reviews)
"The menu was fresh but was also quite minimum. We were happy with it. We would happily recommend living with Salvo for visiting Syracuse. The location is well located in the city in a quiet neighbourhood, importantly it feels safe. "
United Kingdom
Kumar
The price is ฿3,071
฿3,501 total
includes taxes & fees
18 Oct - 19 Oct
B&B Kosmos
A swimming pool with lounge chairs and umbrellas, surrounded by buildings with arched windows and palm trees.

2. Hotel Relax

Hotel Relax
4.0 star property
Epipoli
8.2 out of 10, Very good, (35 reviews)
"Good breakfast and nice pool. Pool rules were strange snd not matching the written ones. Easy parking"
United Kingdom
Fabrizio
The price is ฿5,351
฿6,100 total
includes taxes & fees
27 Sept - 28 Sept
Hotel Relax
A poolside setting with a person relaxing, a table with a drink and fruit, and a view of the pool and chairs in the background.

3. Hotel Parco delle Fontane

Hotel Parco delle Fontane
4.0 star property
Tiche, 1.5 km from Epipoli
9.2 out of 10, Wonderful, (307 reviews)
"Great staff very clean great food beautiful pool we loved it ♥️"
United States
Tony
The price is ฿5,177
฿5,902 total
includes taxes & fees
25 Sept - 26 Sept
Hotel Parco delle Fontane
A historic building with a central entrance, multiple balconies, and a large potted plant in front.

4. Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
4.0 star property
Ortigia, 4.6 km from Epipoli
9.6 out of 10, Exceptional, (1,000 reviews)
"Fantastic property, fab breakfast and lovely staff, what more could you want!"
United Kingdom
Rachael
The price is ฿11,986
฿13,566 total
includes taxes & fees
17 Oct - 18 Oct
Algila' Ortigia Charme Hotel
A poolside area with lounge chairs and umbrellas, a clear blue pool, and a building with balconies.

5. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
5.0 star property
Ortigia, 4.8 km from Epipoli
9.2 out of 10, Wonderful, (100 reviews)
"Clean & beautifully maintained hotel. Better for those who prefer a larger setting than a boutique hotel. Small but comfortable pool area. Great rooftop with amazing sunset views and kudos to our wonderful waiter Fabio."
United States
Laura
The price is ฿23,467
฿26,192 total
includes taxes & fees
29 Sept - 30 Sept
Grand Hotel Des Ètrangers - The Leading Hotels of the World
A balcony with a view of the sea, featuring a metal railing and potted plants.

6. Domus Mariae Albergo

Domus Mariae Albergo
3.0 star property
Ortigia, 4.7 km from Epipoli
9.2 out of 10, Wonderful, (388 reviews)
"Perfect staff perfect location hotel very clean"
United States
Marino
The price is ฿4,192
฿4,779 total
includes taxes & fees
26 Sept - 27 Sept
Domus Mariae Albergo
A rooftop terrace with lounge chairs, a hot tub, and a view of palm trees and buildings.

7. Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia, 3.7 km from Epipoli
9.4 out of 10, Exceptional, (296 reviews)
"Lovely hotel in a great spot, very helpful staff."
Australia
Mandy
The price is ฿6,884
฿7,953 total
includes taxes & fees
24 Oct - 25 Oct
Caportigia Boutique Hotel
A coastal terrace with wicker furniture, striped umbrellas, and a rocky backdrop.

8. Grand Hotel Villa Politi

Grand Hotel Villa Politi
4.0 star property
Grottasanta, 3.6 km from Epipoli
8.6 out of 10, Excellent, (975 reviews)
"lovely hotel beautiful quiet pool breakfast was plentiful with lots of choice"
United Kingdom
Michelle
The price is ฿4,172
฿4,757 total
includes taxes & fees
25 Oct - 26 Oct
Grand Hotel Villa Politi
A large, historic building with multiple floors, a prominent tower, and a waterfront marina with boats.

9. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
5.0 star property
Ortigia, 4.1 km from Epipoli
9.2 out of 10, Wonderful, (278 reviews)
"Good option to stay close to downtown and very exclusive hotel. Breakfast is really good."
Mexico
ALFONSO
The price is ฿19,301
฿21,611 total
includes taxes & fees
27 Sept - 28 Sept
Ortea Palace Hotel, Sicily, Autograph Collection
A riverside walkway with people walking and sitting, overlooking a body of water.

10. Charme Hotel Henry's House

Charme Hotel Henry's House
4.0 star property
Ortigia, 5 km from Epipoli
9.6 out of 10, Exceptional, (352 reviews)
"This hotel is an amazing place. The staff are so friendly, the location is perfect and beautiful, and the hotel itself is stunning. I loved all of the art, and the terrace was one of my favorite places in all of Sicilia. Highly recommend!"
United States
Komal
The price is ฿10,961
฿12,437 total
includes taxes & fees
25 Oct - 26 Oct
Charme Hotel Henry's House
A bakery display with various baked goods and a sign indicating apple and jam cake.

11. UNA Hotels One Siracusa Wellness & SPA

UNA Hotels One Siracusa Wellness & SPA
4.0 star property
Grottasanta, 3.6 km from Epipoli
8.6 out of 10, Excellent, (551 reviews)
"It’s a really beautiful hotel. Great staff, great food, AC works, beautiful spa. It’s in central place but not in the midst of all the chaos at the same time!"
United States
Tanasha
The price is ฿4,499
฿5,129 total
includes taxes & fees
25 Oct - 26 Oct
UNA Hotels One Siracusa Wellness & SPA
A balcony with a view of the sea, a cactus, and potted plants.

12. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
5.0 star property
Ortigia, 4.3 km from Epipoli
9.0 out of 10, Wonderful, (627 reviews)
"Beautiful old world charm.."
United States
NINA
The price is ฿11,787
฿13,345 total
includes taxes & fees
7 Oct - 8 Oct
Grand Hotel Ortigia Siracusa
A woman holding a wine glass on a balcony overlooking a street with historic buildings and a clock tower.

13. Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
4.0 star property
Ortigia, 4.7 km from Epipoli
9.4 out of 10, Exceptional, (693 reviews)
"Amazing stay! This was hands down our favorite hotel of the entire trip. The staff was incredible, the room was amazing, and the location was perfect. We couldn’t have asked for a better experience!"
United States
Kathryn
The price is ฿10,032
฿11,416 total
includes taxes & fees
25 Oct - 26 Oct
Palazzo Artemide - VRetreats, SLH Collection
A hotel room with a bed, a small table with a glass of wine, and a potted plant.

14. Byssus Suites

Byssus Suites
3.4 km from Epipoli
9.8 out of 10, Exceptional, (50 reviews)
"Super modern room (we had a Delux Suite), excellent breakfast too."
United Kingdom
E J
The price is ฿7,755
฿8,840 total
includes taxes & fees
26 Sept - 27 Sept
Byssus Suites
A hotel entrance with a name sign, a potted plant, and a staircase.

15. Hotel Panorama

Hotel Panorama
4.0 star property
Neapolis, 2 km from Epipoli
7.6 out of 10, Good, (157 reviews)
"The property is dated and the bathroom are extremely small"
United States
rosario
The price is ฿3,123
฿3,435 total
includes taxes & fees
7 Oct - 8 Oct
Hotel Panorama
A hot tub with a view of the sea, wicker chairs, and a table with drinks and flowers.

16. Maniace Boutique Hotel Ortigia UNA Esperienze

Maniace Boutique Hotel Ortigia UNA Esperienze
Ortigia, 4.9 km from Epipoli
10.0 out of 10, Exceptional, (103 reviews)
"Very nice property, well maintained, rooms was clean, staff is very coporative, enjoyed our stay"
United States
Asha
The price is ฿12,952
฿14,627 total
includes taxes & fees
19 Oct - 20 Oct
Maniace Boutique Hotel Ortigia UNA Esperienze
A hotel room with a large bed, a window with a view of buildings, a bedside table with a lamp, and a mirror on the wall.

17. Hotel Como

Hotel Como
3.0 star property
3.2 km from Epipoli
7.8 out of 10, Good, (448 reviews)
"Location is just across train station."
United States
Yinan
The price is ฿2,258
฿2,574 total
includes taxes & fees
15 Oct - 16 Oct
Hotel Como
An outdoor swimming pool with a wooden deck, surrounded by white umbrellas and lounge chairs.

18. Mercure Siracusa Prometeo

Mercure Siracusa Prometeo
4.0 star property
Neapolis, 2.7 km from Epipoli
9.0 out of 10, Wonderful, (505 reviews)
"We loved our stay here in Syracuse. We could walk to several historical attractions and even better we could walk to Ortigia. Be sure to book a sunset cruise. It was so beautiful and a lot of fun. It's only a 5-10 minute walk to catch the bus to the airport. Another plus! We highly recommend this hotel."
United States
Stephanie
The price is ฿3,595
฿4,478 total
includes taxes & fees
25 Oct - 26 Oct
Mercure Siracusa Prometeo
A modern hotel room with a flat-screen TV mounted on a dark wall, a white desk with a remote control, a bed with a black and white patterned bedspread, and a window with curtains.

19. Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia, 3.8 km from Epipoli
9.0 out of 10, Wonderful, (289 reviews)
"A really nice room, the bed was extremely comfortable and the staff were very friendly."
United Kingdom
Michael
The price is ฿2,837
฿3,234 total
includes taxes & fees
19 Oct - 20 Oct
Nostos rooms & Apartments
An aerial view of a resort with multiple swimming pools, palm trees, and a clear view of the coastline.

20. Minareto

Minareto
5.0 star property
6.6 km from Epipoli
8.8 out of 10, Excellent, (277 reviews)
"Nice facilities"
United Kingdom
Lekhbiro
The price is ฿14,492
฿16,322 total
includes taxes & fees
24 Oct - 25 Oct
Minareto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Epipoli

Find the best Epipoli areas for the activities you enjoy most.
A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Teatro dei Pupi or Cathedral of Syracuse.

A waterfront with a crowd, buildings, and a sunset.
Photo by Gatanass
Open Photo by Gatanass

Santa Lucia

Santa Lucia is noteworthy for its historical sites, and you can make a stop at top attractions like Porto Piccolo and Ionian Sea.

Ancient ruins with a large amphitheater surrounded by trees.
Photo by William Keller
Open Photo by William Keller

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

A natural rock arch over a body of water with people paddling in kayaks.

Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

Top Epipoli Hotel Reviews

Caportigia Boutique Hotel

Caportigia Boutique Hotel

10/10 Excellent
"Super friendly and helpful staff. Clean room. Close to everything. The only downside was parking. I wish they had a valet outside the hotel to park your car for you."
Claudio 1-night trip
Posted 2 days ago
Caportigia Boutique Hotel

Frequently asked questions

What is Epipoli like?
Travellers to the Epipoli neighbourhood in Syracuse will be sure to enjoy their stay.
What's a favourite place to stay in Epipoli?
Based on our traveller data, Hotel Relax is one of the top choices for your stay in Epipoli. This hotel offers a full-service spa and a restaurant.
How many hotels are there in the Epipoli area?
When you want to find places to stay in Syracuse, start by booking one of Expedia's 7 hotels and other accommodation options in Epipoli.
If I need to cancel my hotel reservation in Epipoli, will I receive a refund?
Yes, you'll find most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals in Epipoli.
What can I see and do in this Syracuse neighbourhood?
A few places to visit in the area around Epipoli include Cantine Pupillo, Greek Theatre of Syracuse and Latomia del Paradiso. Rope-makers' Cave and Ear of Dionysius are also worth a visit when you're out sightseeing in Syracuse.

Explore a world of travel with Expedia