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Top Trending Hotels Near Downtown, Seneca

Free daily on-the-go breakfast
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 star property
Downtown
8.0 out of 10, Very good, (664)
"Friendly check in, clean room."
United States
connie
The price is ฿2,421
฿2,856 total
includes taxes & fees
27 Dec - 28 Dec
Quality Inn Seneca Clemson Area US-123
Exterior
Super 8 by Wyndham Anderson/Clemson Area

Super 8 by Wyndham Anderson/Clemson Area

2.5 star property
29.9 km from Downtown
6.4 out of 10, (260)
"Service was great and our rooms were clean"
United States
Mary Frances
The price is ฿1,905
฿2,115 total
includes taxes & fees
1 Jan - 2 Jan 2026
Super 8 by Wyndham Anderson/Clemson Area
Reception
Quality Inn Clemson near University

Quality Inn Clemson near University

2.5 star property
29.6 km from Downtown
7.0 out of 10, Good, (887)
"Bueno was "
Mexico
Alejandro
The price is ฿1,399
฿1,553 total
includes taxes & fees
18 Dec - 19 Dec
Quality Inn Clemson near University
Meeting facility
Holiday Inn Anderson by IHG

Holiday Inn Anderson by IHG

3.0 star property
29.5 km from Downtown
8.8 out of 10, Excellent, (694)
"Clean up kept hotel, friendly staff. Plenty of food options "
United States
Jordan
The price is ฿3,490
฿3,874 total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Anderson by IHG
Lobby
Americas Best Value Inn Anderson, SC

Americas Best Value Inn Anderson, SC

2.0 star property
27.9 km from Downtown
5.8 out of 10, (150)
"Nice little motel with friendly owners. Beds were a little too firm and breakfast a bit lacking, but for the price, it was fine. We enjoyed our stay. "
United States
Heather
The price is ฿2,017
฿2,239 total
includes taxes & fees
3 Dec - 4 Dec
Americas Best Value Inn Anderson, SC
Exterior
Hilton Garden Inn Anderson

Hilton Garden Inn Anderson

3.0 star property
25.7 km from Downtown
9.0 out of 10, Wonderful, (671)
"Clean Room "
United States
Cynthia
The price is ฿3,305
฿3,668 total
includes taxes & fees
9 Dec - 10 Dec
Hilton Garden Inn Anderson
Exterior
Woodspring Suites Anderson North I-85

Woodspring Suites Anderson North I-85

2.5 star property
25.4 km from Downtown
7.6 out of 10, Good, (56)
"Everything was perfect, the room was clean, and the staff was nice."
United States
Johnny
The price is ฿2,306
฿2,559 total
includes taxes & fees
3 Dec - 4 Dec
Woodspring Suites Anderson North I-85
Free daily continental breakfast
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2.0 star property
25.6 km from Downtown
7.8 out of 10, Good, (1026)
"Like most motels, it was kind of sketch, but it made do. Honestly a pretty decent place to stay. "
United States
Liam
The price is ฿2,014
฿2,236 total
includes taxes & fees
7 Dec - 8 Dec
Days Inn by Wyndham Anderson
Coffee service
Comfort Suites Anderson-Clemson

Comfort Suites Anderson-Clemson

2.5 star property
25.3 km from Downtown
8.4 out of 10, Very good, (1001)
"Very nice Hotel."
United States
Richard
The price is ฿3,430
฿3,807 total
includes taxes & fees
7 Dec - 8 Dec
Comfort Suites Anderson-Clemson
Standard Room, 2 Queen Beds, Non Smoking | Free WiFi, bed sheets
Rodeway Inn

Rodeway Inn

2.0 star property
25.5 km from Downtown
7.8 out of 10, Good, (315)
"Nice beds"
United States
Tammy
The price is ฿1,921
฿2,133 total
includes taxes & fees
30 Dec - 31 Dec
Rodeway Inn
Property amenity
Residence Inn by Marriott Anderson Clemson

Residence Inn by Marriott Anderson Clemson

3.0 star property
25.1 km from Downtown
9.8 out of 10, Exceptional, (86)
"Very clean. Breakfast was great. Location was very convenient. Room was very spacious for the price "
United States
linda gaye allen
The price is ฿4,579
฿5,083 total
includes taxes & fees
21 Dec - 22 Dec
Residence Inn by Marriott Anderson Clemson
Outdoor pool
Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson

2.5 star property
25 km from Downtown
7.0 out of 10, Good, (839)
"Clean attractive room and friendly staff. "
Canada
Lisa
The price is ฿1,911
฿2,121 total
includes taxes & fees
8 Dec - 9 Dec
Baymont by Wyndham Anderson Clemson
Exterior
Hampton Inn Anderson

Hampton Inn Anderson

2.5 star property
25 km from Downtown
9.0 out of 10, Wonderful, (399)
"Staff was super friendly and helpful. Please consider blackout blinds /curtains for the room "
United States
Lisa
The price is ฿3,635
฿4,035 total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn Anderson
Reception
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

2.5 star property
25 km from Downtown
9.0 out of 10, Wonderful, (579)
"It was great. Room was clean and staff was friendly. "
United States
Veronica
The price is ฿3,305
฿3,668 total
includes taxes & fees
7 Dec - 8 Dec
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Outdoor pool, open 9:00 AM to 9:00 PM, pool loungers
Fairfield Inn & Suites by Marriott Anderson Clemson

Fairfield Inn & Suites by Marriott Anderson Clemson

2.5 star property
25 km from Downtown
9.0 out of 10, Wonderful, (566)
"Clean room staff was verynice!"
United States
Laura Jo
The price is ฿2,695
฿2,991 total
includes taxes & fees
21 Dec - 22 Dec
Fairfield Inn & Suites by Marriott Anderson Clemson
Free buffet breakfast
Country Inn & Suites by Radisson, Anderson, SC

Country Inn & Suites by Radisson, Anderson, SC

2.5 star property
25 km from Downtown
8.4 out of 10, Very good, (1006)
"Clean room, staff was freiendly."
United States
Sherie
The price is ฿3,574
฿3,967 total
includes taxes & fees
9 Dec - 10 Dec
Country Inn & Suites by Radisson, Anderson, SC
Lobby
Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson

2.0 star property
24.8 km from Downtown
8.2 out of 10, Very good, (1008)
"Room was clean, staff was nice! "
United States
Martina
The price is ฿2,559
฿2,840 total
includes taxes & fees
3 Dec - 4 Dec
Microtel Inn & Suites by Wyndham Anderson/Clemson
Restaurant
Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast

4.0 star property
16.3 km from Downtown
10.0 out of 10, Exceptional, (76)
"The owners are amazing. Comfy rooms, stellar breakfast and good people. "
United States
Renee
The price is ฿4,028
฿6,072 total
includes taxes & fees
3 Dec - 4 Dec
Liberty Hall Bed and Breakfast
Signature House, 4 Bedrooms, Patio | Living room | 43-inch Smart TV with cable channels, TV, fireplace
Lake Hartwell Frank Howard Home Clemson

Lake Hartwell Frank Howard Home Clemson

4.0 star property
17.3 km from Downtown
The price is ฿3,747
฿9,490 total
includes taxes & fees
7 Dec - 8 Dec
Lake Hartwell Frank Howard Home Clemson
Reception hall
The Inn at Patrick Square

The Inn at Patrick Square

3.5 star property
15.2 km from Downtown
9.8 out of 10, Exceptional, (781)
"This is one of our favorite hotels while in Clemson. Several restaurants and a wine bar and a brewery just steps away. "
United States
Stephanie
The price is ฿4,771
฿5,296 total
includes taxes & fees
3 Dec - 4 Dec
The Inn at Patrick Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Downtown

Find the best Downtown areas for the activities you enjoy most.

Serenity Bay

When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.

Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit Lake Keowee and World of Energy.

Indian Oaks

While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like The Gauntlet and Seneca Historic District.

Keowee Plantation

While Keowee Plantation isn't home to many top sights, Seneca Historic District and Keowee Reservoir are some notable places to visit nearby.

Top Downtown Hotel Reviews

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

10/10 Excellent
"Property, room, and front desk were all very nice. Safety strips in the bathtub would be my only suggestion. "
Norma 1-night trip
Posted 4 days ago
Quality Inn Seneca Clemson Area US-123

Explore a world of travel with Expedia

Frequently asked questions

What is Downtown like?
Travellers to the Downtown neighbourhood in Seneca will be sure to enjoy their stay. Make sure that you visit Seneca Historic District and The Gauntlet as part of your Downtown travel plans.
Where is the best place to stay in Downtown?
Based on Expedia customer reviews, Quality Inn Seneca Clemson Area US-123 is the highest ranked property in Downtown. This hotel offers free breakfast and free parking.
How many hotels will I be able to find in Downtown?
Expedia has 9 Downtown hotels and other accommodation options, and one might make a good home base for venturing out into the greater Seneca area.
If I need to cancel my hotel reservation in Downtown, will I receive a refund?
Yes! You'll find that most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to review the best deals in Downtown.
What can I see and do in this Seneca neighbourhood?
Seneca Historic District, The Gauntlet and Bertha Lee Strickland Cultural Museum are just a few attractions to check out in Downtown. As you're discovering the neighbourhood, Oconee County Library Seneca Branch and Seneca City Hall are some other places worth a visit. Golden Corner Plaza, Oconee Community Theatre and Applewood Shopping Center are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, make sure that you visit other sights such as Wyndham Plaza or Cross Creek Plantation Golf.