Find hotels in Depew, NY from ฿1,771

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Depew hotels

Best Western Buffalo Inn & Suites

Best Western Buffalo Inn & Suites
2.5 star property
Buffalo
8.8 out of 10, Excellent, (910 reviews)
"Great stay staff and property we love it "
Canada
Ezio
The price is ฿3,073
฿3,496 total
includes taxes & fees
19 Apr - 20 Apr
Best Western Buffalo Inn & Suites

Lockport Inn & Suites

Lockport Inn & Suites
2.0 star property
Lockport
9.2 out of 10, Wonderful, (1,001 reviews)
"We enjoyed ouf stay at this hidden away gem! Bed was super comfy and jacuzzi was welcomed addition! We will definitely revisit this propery!"
United States
Tracey
The price is ฿3,172
฿3,584 total
includes taxes & fees
13 Apr - 14 Apr
Lockport Inn & Suites

Roycroft Inn

Roycroft Inn
3.5 star property
East Aurora
9.6 out of 10, Exceptional, (872 reviews)
"Beautiful & historic inn with a wonderful staff & restaurant. "
United States
Karen
The price is ฿4,731
฿5,287 total
includes taxes & fees
20 Apr - 21 Apr
Roycroft Inn

Hampton Inn East Aurora

Hampton Inn East Aurora
2.5 star property
East Aurora
9.4 out of 10, Exceptional, (1,004 reviews)
"Incredibly friendly staff at check in. Room was beautiful and very clean. "
United States
Linda
The price is ฿4,702
฿5,349 total
includes taxes & fees
26 Apr - 27 Apr
Hampton Inn East Aurora

Spark by Hilton Lockport

Spark by Hilton Lockport
3.0 star property
Lockport
7.2 out of 10, Good, (104 reviews)
"Great stay, thanks!"
Canada
Shirmilla
The price is ฿2,657
฿3,002 total
includes taxes & fees
28 Apr - 29 Apr
Spark by Hilton Lockport

Holiday Inn Express Grand Island - Niagara Falls by IHG

Holiday Inn Express Grand Island - Niagara Falls by IHG
2.5 star property
Grand Island
9.0 out of 10, Wonderful, (1,753 reviews)
"Rooms were very clean and staff were friendly! Great coffee too! "
United States
Mackenzie
The price is ฿3,652
฿4,155 total
includes taxes & fees
26 Apr - 27 Apr
Holiday Inn Express Grand Island - Niagara Falls by IHG

Econo Lodge Darien Lakes

Econo Lodge Darien Lakes
2.0 star property
Corfu
7.8 out of 10, Good, (815 reviews)
"Staff were prompt with check-in and very direct. It was helpful. "
United States
Anna
The price is ฿2,491
฿2,765 total
includes taxes & fees
3 May - 4 May
Econo Lodge Darien Lakes

Clarence Inn

Clarence Inn
2.0 star property
Clarence
8.2 out of 10, Very good, (299 reviews)
"Great service quiet place and friendly people."
United States
Larry
The price is ฿3,172
฿3,544 total
includes taxes & fees
13 Apr - 14 Apr
Clarence Inn

AAshram Hotel by Niagara River

AAshram Hotel by Niagara River
2.5 star property
La Salle
7.8 out of 10, Good, (1,002 reviews)
"Nice stay. "
United States
John
The price is ฿1,922
฿2,191 total
includes taxes & fees
13 Apr - 14 Apr
AAshram Hotel by Niagara River

Best Western Summit Inn

Best Western Summit Inn
2.5 star property
Niagara Falls
8.6 out of 10, Excellent, (1,467 reviews)
"The hotel was a great value - very clean and well kept. The staff were friendly and helpful. "
United States
Elaine
The price is ฿2,371
฿2,703 total
includes taxes & fees
13 Apr - 14 Apr
Best Western Summit Inn

Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport
2.5 star property
Buffalo
8.0 out of 10, Very good, (2,051 reviews)
"Clean Room, great location, breakfast is good as well"
United States
PAULA PAVALICINI
The price is ฿2,156
฿2,452 total
includes taxes & fees
29 Apr - 30 Apr
Sleep Inn & Suites Buffalo Airport

Days Inn & Suites by Wyndham Niagara Falls/Buffalo

Days Inn & Suites by Wyndham Niagara Falls/Buffalo
2.5 star property
Niagara Falls
8.0 out of 10, Very good, (1,002 reviews)
"Wonderful stay will stay again"
Canada
christine
The price is ฿2,587
฿2,923 total
includes taxes & fees
19 Apr - 20 Apr
Days Inn & Suites by Wyndham Niagara Falls/Buffalo

Moonlite Motel Niagara Falls

Moonlite Motel Niagara Falls
2.0 star property
La Salle
9.0 out of 10, Wonderful, (1,000 reviews)
"Amazing place !"
United States
Mirzobek
The price is ฿2,349
฿2,678 total
includes taxes & fees
3 May - 4 May
Moonlite Motel Niagara Falls

Hampton Inn Buffalo South/I-90

Hampton Inn Buffalo South/I-90
2.5 star property
Buffalo
8.6 out of 10, Excellent, (1,001 reviews)
"Nice place"
United States
Joseph
The price is ฿3,652
฿4,154 total
includes taxes & fees
19 Apr - 20 Apr
Hampton Inn Buffalo South/I-90

Quality Inn Near Walden Galleria Mall

Quality Inn Near Walden Galleria Mall
2.5 star property
Buffalo
8.0 out of 10, Very good, (1,012 reviews)
"Room was clean - check-in was effortless - hot coffee and a bite to eat for breakfast - convenient location - overall great experience!"
United States
Lorraine
The price is ฿3,344
฿3,804 total
includes taxes & fees
14 Apr - 15 Apr
Quality Inn Near Walden Galleria Mall

Holiday Inn Express Amherst - Lockport by IHG

Holiday Inn Express Amherst - Lockport by IHG
2.5 star property
Lockport
9.2 out of 10, Wonderful, (768 reviews)
"Clean and comfortable accommodations, friendly staff and a great breakfast spread!"
United States
Andrea
The price is ฿3,909
฿4,417 total
includes taxes & fees
26 Apr - 27 Apr
Holiday Inn Express Amherst - Lockport by IHG

Red Roof Inn Buffalo - Niagara Airport

Red Roof Inn Buffalo - Niagara Airport
2.0 star property
Bowmansville
7.2 out of 10, Good, (1,004 reviews)
"Great price and fairly clean rooms. "
United States
amber
The price is ฿1,936
฿2,203 total
includes taxes & fees
16 Apr - 17 Apr
Red Roof Inn Buffalo - Niagara Airport

Salvatores Grand Hotel

Salvatores Grand Hotel
3.0 star property
Buffalo
9.6 out of 10, Exceptional, (1,001 reviews)
"Beautiful hotel , excellent food, worth every penny. "
United States
Andrea
The price is ฿4,133
฿4,701 total
includes taxes & fees
13 Apr - 14 Apr
Salvatores Grand Hotel

Hampton Inn Buffalo-Hamburg

Hampton Inn Buffalo-Hamburg
2.5 star property
Hamburg
9.0 out of 10, Wonderful, (1,005 reviews)
"Friendly staff, clean room, and excellent breakfast! "
United States
Margaret
The price is ฿3,381
฿3,846 total
includes taxes & fees
27 Apr - 28 Apr
Hampton Inn Buffalo-Hamburg

Comfort Inn & Suites Niagara Falls Blvd USA

Comfort Inn & Suites Niagara Falls Blvd USA
2.5 star property
La Salle
8.8 out of 10, Excellent, (1,356 reviews)
"Close to shopping and restaurants. Clean and conveniently located close to the Canadian border."
Canada
shelley
The price is ฿2,342
฿2,670 total
includes taxes & fees
26 Apr - 27 Apr
Comfort Inn & Suites Niagara Falls Blvd USA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Depew Hotel Reviews

More cheap stays in Depew

Frequently asked questions

What's the best place for a stay in Depew?
Located 2.5 mi (4 km) from the heart of Depew, Buffalo Airport Hotel is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Holiday Inn Express Grand Island - Niagara Falls by IHG and M Hotel Buffalo. See all available top hotels, or vacation rentals in Depew.
If I need to cancel my hotel reservation in Depew, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Depew.
What are some accommodation options with pools in Depew?
Holiday Inn Express Grand Island - Niagara Falls by IHG: Offers a snack bar/deli, an indoor pool and daily. M Hotel Buffalo and Hyatt Regency Buffalo / Hotel and Conference Center are a couple of other choices that offer an on-site pool. View all hotels with pools in Depew.
What is staying in Depew like?
Visitors can enjoy all that Depew has to offer, including the shopping, restaurants and sporting events. Tourists can also enjoy so much more including its waterfalls. In Depew, there are 15 hotels and other accommodation options to choose from. Find out more about Depew.
What should I see while I'm in Depew?
Places to visit in the wider area include Holiday Twin Rinks, Walden Galleria Mall and Samuel's Grande Manor. You'll also find Glen Falls and Buffalo Central Terminal in the area. Take a look at what more there is to see and do in Expedia's Depew guide.
How can I get around Depew?
If you want to explore the larger area, hop on a train at Buffalo-Depew Station. If you want to venture out around the area, you may want a rental car in Depew for your journey.
What's the seasonal weather like in Depew?
The hottest months are usually July and August, with an average temperature of 20°C, while the coldest months are January and February, with an average of -1°C. The snowiest months in Depew are January, March, February and December, with each month seeing an average of 43 cm of snowfall.

Explore a world of travel with Expedia