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Check prices for these dates

Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

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Our top choices for Cherokee Seneca hotels

A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.

1. Holiday Inn Express Louisville Airport Expo Center by IHG

Holiday Inn Express Louisville Airport Expo Center by IHG
2.5 star property
4 km from Cherokee Seneca
8.6 out of 10, Excellent, (1,005 reviews)
"nice clean place and a good free breakfast is a +"
United States
Cliff
The price is ฿2,951
฿3,472 total
includes taxes & fees
26 Oct - 27 Oct
Holiday Inn Express Louisville Airport Expo Center by IHG
A Hilton Garden Inn hotel with a modern design, multiple floors, and a well-lit entrance.

2. Hilton Garden Inn Louisville Mall of St. Matthews

Hilton Garden Inn Louisville Mall of St. Matthews
3.0 star property
St. Matthews, 5.2 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1,007 reviews)
"Nice place, clean room, comfortable bed, good shower. Can't ask for more."
United States
Emily
The price is ฿3,134
฿3,688 total
includes taxes & fees
1 Nov - 2 Nov
Hilton Garden Inn Louisville Mall of St. Matthews
A modern dining area with multiple tables and chairs, a kitchen area with stainless steel appliances, and a large window with blue curtains.

3. Wingate by Wyndham Louisville Fair and Expo

Wingate by Wyndham Louisville Fair and Expo
3.0 star property
3.7 km from Cherokee Seneca
8.4 out of 10, Very good, (1,241 reviews)
"We had a wonderful stay!"
United States
Bobi
The price is ฿2,337
฿2,750 total
includes taxes & fees
1 Nov - 2 Nov
Wingate by Wyndham Louisville Fair and Expo
A bar area with multiple seating options and a large display of liquor bottles.

4. Derby City Gaming & Hotel - A Churchill Downs Property (Adults Only)

Derby City Gaming & Hotel - A Churchill Downs Property (Adults Only)
4.0 star property
6 km from Cherokee Seneca
9.4 out of 10, Exceptional, (2,563 reviews)
"The room was amazing and the staff was great."
United States
Mark
The price is ฿3,751
฿4,413 total
includes taxes & fees
26 Oct - 27 Oct
Derby City Gaming & Hotel - A Churchill Downs Property (Adults Only)
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

5. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,380 reviews)
"Excellent stay"
United States
Frances
The price is ฿4,922
฿5,791 total
includes taxes & fees
29 Oct - 30 Oct
Embassy Suites Louisville Downtown
An indoor swimming pool with lounge chairs and umbrellas, surrounded by arched windows and a tiled floor.

6. Hawthorn Suites by Wyndham Louisville East

Hawthorn Suites by Wyndham Louisville East
3.0 star property
St. Matthews, 5.2 km from Cherokee Seneca
8.6 out of 10, Excellent, (1,121 reviews)
"Nice property. Enjoyed our stay."
United States
Lucia
The price is ฿2,722
฿3,203 total
includes taxes & fees
25 Oct - 26 Oct
Hawthorn Suites by Wyndham Louisville East
A Courtyard by Marriott hotel with a modern facade, multiple floors, and a well-lit entrance.

7. Courtyard by Marriott Louisville Airport

Courtyard by Marriott Louisville Airport
3.0 star property
7.1 km from Cherokee Seneca
9.2 out of 10, Wonderful, (480 reviews)
"nice place great staff"
United States
SHEILA
The price is ฿2,988
฿3,515 total
includes taxes & fees
18 Oct - 19 Oct
Courtyard by Marriott Louisville Airport
A modern lobby with a curved reception desk, seating area with sofas and armchairs, and a central coffee table.

8. Springhill Suites by Marriott Louisville Airport

Springhill Suites by Marriott Louisville Airport
3.0 star property
Fairgrounds, 7.1 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,003 reviews)
"Clean rooms easy access around town!"
United States
jamie
The price is ฿2,951
฿3,472 total
includes taxes & fees
25 Oct - 26 Oct
Springhill Suites by Marriott Louisville Airport
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

9. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 6.2 km from Cherokee Seneca
9.4 out of 10, Exceptional, (2,179 reviews)
"This was the perfect location and wonderful place to stay"
United States
Samantha
The price is ฿8,517
฿10,021 total
includes taxes & fees
30 Oct - 31 Oct
Omni Louisville Hotel
A grand lobby with ornate columns, plush seating, and a chandelier.

10. The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1,366 reviews)
"Great historic hotel, friendly staff, excellent rates, superb bar."
United States
John
The price is ฿4,201
฿4,943 total
includes taxes & fees
25 Oct - 26 Oct
The Brown Hotel
A hotel corridor with a snack bar, refrigerated display, and a long hallway with a patterned carpet.

11. Hampton Inn Louisville-Airport

Hampton Inn Louisville-Airport
2.5 star property
Fairgrounds, 7.2 km from Cherokee Seneca
8.6 out of 10, Excellent, (1,001 reviews)
"Great Stay"
United States
Amanda
The price is ฿3,217
฿3,785 total
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn Louisville-Airport
A modern dining area with a long counter and multiple tables, large windows, and a flat-screen TV mounted on the wall.

12. Hilton Garden Inn Louisville Airport

Hilton Garden Inn Louisville Airport
3.0 star property
Fairgrounds, 6.9 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,000 reviews)
"great location, great staff, easy airport shuttle rides. we loved the breakfast buffet too."
United States
Brian
The price is ฿4,288
฿5,045 total
includes taxes & fees
16 Oct - 17 Oct
Hilton Garden Inn Louisville Airport
A reception desk with a wooden panel wall, a circular decorative piece, and a sign indicating 'Marriott Bonvoy'.

13. Fairfield Inn & Suites by Marriott Louisville Airport

Fairfield Inn & Suites by Marriott Louisville Airport
3.0 star property
7.3 km from Cherokee Seneca
8.8 out of 10, Excellent, (820 reviews)
"This hotel is awesome! Super clean, with amazing, delicious hot breakfast, very convenient location. Definitely will be back when I travel to Louisville."
United States
Irina
The price is ฿3,107
฿3,655 total
includes taxes & fees
14 Oct - 15 Oct
Fairfield Inn & Suites by Marriott Louisville Airport
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

14. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 6.5 km from Cherokee Seneca
9.0 out of 10, Wonderful, (4,365 reviews)
"Great place"
United States
Phillip
The price is ฿4,844
฿5,699 total
includes taxes & fees
27 Oct - 28 Oct
Galt House Hotel Trademark Collection by Wyndham
An indoor swimming pool with clear blue water, surrounded by large windows offering a view of the outdoors.

15. Hampton Inn & Suites By Hilton Louisville East Oxmoor

Hampton Inn & Suites By Hilton Louisville East Oxmoor
2.5 star property
5.8 km from Cherokee Seneca
9.6 out of 10, Exceptional, (263 reviews)
"Room was very spacious, bathroom had great lighting, bed was extremely comfortable!!"
United States
Richard
The price is ฿3,671
฿4,319 total
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn & Suites By Hilton Louisville East Oxmoor
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

16. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 4.9 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1,138 reviews)
"Great stay!"
United States
Addison
The price is ฿4,097
฿4,820 total
includes taxes & fees
25 Oct - 26 Oct
Tempo By Hilton Louisville Downtown Nulu
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.

17. Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville, 6.2 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,008 reviews)
"The room was clean and the hotel was in a great location."
United States
Veronica
The price is ฿7,468
฿8,787 total
includes taxes & fees
7 Nov - 8 Nov
Louisville Marriott Downtown
A modern indoor seating area with wooden tables and chairs, large windows offering a view of the outdoors, and a mix of red and beige seating.

18. Tru by Hilton Louisville Airport

Tru by Hilton Louisville Airport
2.5 star property
Fairgrounds, 7.2 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,002 reviews)
"Great plqce to stay!!!"
United States
Rick
The price is ฿3,078
฿3,622 total
includes taxes & fees
26 Oct - 27 Oct
Tru by Hilton Louisville Airport
A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.

19. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 4.9 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1,098 reviews)
"Great property close to amazing restaurants"
United States
Tyler
The price is ฿4,661
฿5,484 total
includes taxes & fees
8 Nov - 9 Nov
Hotel Genevieve part of JdV by Hyatt
A modern bar area with a circular bar, multiple seating options, and a large screen.

20. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 5.8 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1,004 reviews)
"Great hotel!"
United States
Gordon
The price is ฿3,621
฿4,261 total
includes taxes & fees
9 Nov - 10 Nov
Cambria Hotel Louisville Downtown-Whiskey Row
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Cherokee Seneca

Find the best Cherokee Seneca areas for the activities you enjoy most.
A steamboat docked at a pier with a bridge in the background.

Downtown Louisville

The cultural heart of the city beats with baseball, boxing and music, with sporting fields, live bands and a center for Muhammad Ali, the city’s most famous son.

A nighttime cityscape with a brightly lit bridge and a skyline featuring a prominent dome-shaped building.

St. Matthews

St. Matthews is noteworthy for its shopping, and you can make a stop at top attractions like Mall St. Matthews and Saint Matthews Pavilion Shopping Center.

A nighttime hot air balloon festival with colorful balloons, including one labeled "OLIVER WINERY."
Photo by Hyelsinta
Open Photo by Hyelsinta

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

A city skyline at dusk with illuminated buildings reflecting on the water.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

A historical marker for the Conrad-Caldwell House, detailing its architectural style and history.

Old Louisville

Old Louisville is known for its ample dining options, and you can make a stop by Ohio River Valley and Asia Institute Crane House while in the area.

Top Cherokee Seneca Hotel Reviews

The Brown Hotel

The Brown Hotel

10/10 Excellent
"Clean room & great hotel. Great dinner & breakfast for additional costs. Famous for the hot brown & it didn't disappoint"
Curtis 3-night trip
Posted 3 hours ago
The Brown Hotel

Frequently asked questions

What is Cherokee Seneca like?
You'll be sure to have fun exploring Louisville's Cherokee Seneca neighbourhood.
If I need to cancel my hotel reservation in Cherokee Seneca, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to review the best deals in Cherokee Seneca.
What is there to do around this Louisville neighbourhood?
Peterson-Dumesnil House, Historic Frankfort Avenue and Colonel Sanders' Grave are just a few of the places to visit in and around Cherokee Seneca. Norton Fine Arts Center and Muhammad Ali Gravesite are also worth a visit when you're out sightseeing in Louisville.