Lodging Image

Search Hotels in Cherokee Seneca, Louisville

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
28 Aug - 30 Aug
Next weekend
4 Sep - 6 Sep

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Cherokee Seneca hotels

A Holiday Inn Express hotel with a modern design, featuring a covered parking area and a well-lit entrance.

1. Holiday Inn Express Louisville Airport Expo Center by IHG

Holiday Inn Express Louisville Airport Expo Center by IHG
2.5 star property
4 km from Cherokee Seneca
8.6 out of 10, Excellent, (1,018 reviews)
"Great hotel"
United States
Yisel
The price is ฿3,038
฿3,575 total
includes taxes & fees
31 Aug - 1 Sept
Holiday Inn Express Louisville Airport Expo Center by IHG
A modern dining area with multiple tables and chairs, a kitchen area with stainless steel appliances, and a large window with blue curtains.

2. Wingate by Wyndham Louisville Fair and Expo

Wingate by Wyndham Louisville Fair and Expo
3.0 star property
3.7 km from Cherokee Seneca
8.4 out of 10, Very good, (1,243 reviews)
"Nice for the quick stay"
United States
Jim
The price is ฿2,277
฿2,680 total
includes taxes & fees
14 Sept - 15 Sept
Wingate by Wyndham Louisville Fair and Expo
An outdoor patio with a stone fire pit, wicker furniture, and a stone wall.

3. Residence Inn by Marriott Louisville East/Oxmoor

Residence Inn by Marriott Louisville East/Oxmoor
3.0 star property
5.9 km from Cherokee Seneca
9.6 out of 10, Exceptional, (323 reviews)
"Nice property and breakfast was good selection"
United States
Brandon
The price is ฿5,358
฿6,304 total
includes taxes & fees
28 Aug - 29 Aug
Residence Inn by Marriott Louisville East/Oxmoor
A modern lobby with a curved reception desk, seating area with sofas and armchairs, and a central coffee table.

4. Springhill Suites by Marriott Louisville Airport

Springhill Suites by Marriott Louisville Airport
3.0 star property
Fairgrounds, 7.1 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,010 reviews)
"friendly staff clean facility and easy access to and from airport"
United States
Mary M
The price is ฿3,202
฿3,767 total
includes taxes & fees
30 Aug - 31 Aug
Springhill Suites by Marriott Louisville Airport
A bar area with multiple seating options and a large display of liquor bottles.

5. Derby City Gaming & Hotel - A Churchill Downs Property (Adults Only)

Derby City Gaming & Hotel - A Churchill Downs Property (Adults Only)
4.0 star property
6 km from Cherokee Seneca
9.4 out of 10, Exceptional, (2,474 reviews)
"Amazing stay!"
Canada
Marissa
The price is ฿3,577
฿4,208 total
includes taxes & fees
30 Aug - 31 Aug
Derby City Gaming & Hotel - A Churchill Downs Property (Adults Only)
A rooftop patio with a fire feature, seating, and a view of the sunset.

6. Crowne Plaza Louisville Airport Expo Ctr by IHG

Crowne Plaza Louisville Airport Expo Ctr by IHG
3.5 star property
Fairgrounds, 7 km from Cherokee Seneca
8.8 out of 10, Excellent, (1,796 reviews)
"The hotel was beautiful and the front desk was so nice and helpful checking in. I was very pleased with our stay and will be back!"
United States
Elaine
The price is ฿3,582
฿4,215 total
includes taxes & fees
30 Aug - 31 Aug
Crowne Plaza Louisville Airport Expo Ctr by IHG
A modern restaurant with a mix of booth seating and tables, a wooden accent wall, and a tiled floor.

7. Drury Inn & Suites Louisville North

Drury Inn & Suites Louisville North
3.0 star property
12.5 km from Cherokee Seneca
9.6 out of 10, Exceptional, (1,021 reviews)
"Clean , friendly staff , great area"
Canada
Emily
The price is ฿3,267
฿3,844 total
includes taxes & fees
30 Aug - 31 Aug
Drury Inn & Suites Louisville North
A Hilton Garden Inn hotel with a modern design, multiple floors, and a well-lit entrance.

8. Hilton Garden Inn Louisville Mall of St. Matthews

Hilton Garden Inn Louisville Mall of St. Matthews
3.0 star property
St. Matthews, 5.2 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1,007 reviews)
"Good location Everything was very nice"
United States
Chris
The price is ฿3,242
฿3,814 total
includes taxes & fees
6 Sept - 7 Sept
Hilton Garden Inn Louisville Mall of St. Matthews
A brick building with outdoor seating and a fire pit.

9. TownePlace Suites by Marriott Louisville North

TownePlace Suites by Marriott Louisville North
3.0 star property
6.3 km from Cherokee Seneca
9.2 out of 10, Wonderful, (718 reviews)
"Very happy with my stay. Staff was friendly."
United States
Lisa
The price is ฿4,378
฿4,947 total
includes taxes & fees
8 Sept - 9 Sept
TownePlace Suites by Marriott Louisville North
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

10. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,347 reviews)
"Great place to stay, plenty of places to eat within walking distance."
United States
Spencer
The price is ฿4,260
฿5,012 total
includes taxes & fees
1 Sept - 2 Sept
Embassy Suites Louisville Downtown
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

11. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 4.9 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1,099 reviews)
"Clean, great decor, friendly staff and functional rooms. Enjoyed our stay and will return!"
United States
Jennifer
The price is ฿3,858
฿4,539 total
includes taxes & fees
7 Sept - 8 Sept
Tempo By Hilton Louisville Downtown Nulu

12. Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 7.1 km from Cherokee Seneca
8.8 out of 10, Excellent, (1,783 reviews)
"Super clean room, great staff and awesome parking!"
United States
Arelys
The price is ฿2,793
฿3,287 total
includes taxes & fees
6 Sept - 7 Sept
Holiday Inn Express & Suites Louisville Downtown by IHG
An indoor swimming pool with lounge chairs and umbrellas, surrounded by arched windows and a tiled floor.

13. Hawthorn Suites by Wyndham Louisville East

Hawthorn Suites by Wyndham Louisville East
3.0 star property
St. Matthews, 5.2 km from Cherokee Seneca
8.6 out of 10, Excellent, (1,123 reviews)
"Great stay."
United States
Ty
The price is ฿2,749
฿3,235 total
includes taxes & fees
6 Sept - 7 Sept
Hawthorn Suites by Wyndham Louisville East
A bathroom with a sink, mirror, towel rack, and a shower with a striped curtain.

14. Red Roof Inn Louisville Fair and Expo

Red Roof Inn Louisville Fair and Expo
2.0 star property
4.2 km from Cherokee Seneca
7.6 out of 10, Good, (1,011 reviews)
"Was a nice quiet hotel and very clean"
United States
Christopher
The price is ฿1,958
฿2,303 total
includes taxes & fees
6 Sept - 7 Sept
Red Roof Inn Louisville Fair and Expo

15. Best Western Louisville Airport Expo

Best Western Louisville Airport Expo
2.5 star property
6.2 km from Cherokee Seneca
8.6 out of 10, Excellent, (1,013 reviews)
"Nice staff comfortable beds good breakfast"
United States
Jessica
The price is ฿2,879
฿3,387 total
includes taxes & fees
3 Sept - 4 Sept
Best Western Louisville Airport Expo
A modern bar area with a long counter, multiple seating options including bar stools and round tables, and pendant lighting.

16. Hyatt House Louisville East

Hyatt House Louisville East
2.0 star property
9.2 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1,011 reviews)
"Breakfast was nice , hotel was well kept and clean . Would stay again !"
United States
Dominica
The price is ฿3,430
฿4,036 total
includes taxes & fees
31 Aug - 1 Sept
Hyatt House Louisville East
An indoor swimming pool with clear blue water, surrounded by large windows offering a view of the outdoors.

17. Hampton Inn & Suites By Hilton Louisville East Oxmoor

Hampton Inn & Suites By Hilton Louisville East Oxmoor
2.5 star property
5.8 km from Cherokee Seneca
9.8 out of 10, Exceptional, (245 reviews)
"Stayed for a night and loved it! Close to Norton, awesome shower, and great night’s sleep at a fair price! Would stay again when in Louisville"
United States
Christopher
The price is ฿3,577
฿4,208 total
includes taxes & fees
30 Aug - 31 Aug
Hampton Inn & Suites By Hilton Louisville East Oxmoor
A modern indoor seating area with wooden tables and chairs, large windows offering a view of the outdoors, and a mix of red and beige seating.

18. Tru by Hilton Louisville Airport

Tru by Hilton Louisville Airport
2.5 star property
Fairgrounds, 7.2 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,015 reviews)
"Excellent place to stay near the airport."
United States
Lee Ann
The price is ฿2,793
฿3,286 total
includes taxes & fees
7 Sept - 8 Sept
Tru by Hilton Louisville Airport
A bar area with a counter, multiple shelves of bottles, and bar stools.

19. Holiday Inn Louisville Airport - Fair/Expo by IHG

Holiday Inn Louisville Airport - Fair/Expo by IHG
3.0 star property
Fairgrounds, 7 km from Cherokee Seneca
8.0 out of 10, Very good, (1,003 reviews)
"Very clean room and the beds were really comfortable"
United States
Coleen
The price is ฿3,038
฿3,575 total
includes taxes & fees
30 Aug - 31 Aug
Holiday Inn Louisville Airport - Fair/Expo by IHG

20. Hilton Garden Inn Louisville Airport

Hilton Garden Inn Louisville Airport
3.0 star property
Fairgrounds, 6.9 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,002 reviews)
"Stayed here to move our son into UofL and it’s close to the college. Stay was great, staff was pleasant and room was clean. Will stay here again."
United States
Clara
The price is ฿3,998
฿4,704 total
includes taxes & fees
12 Sept - 13 Sept
Hilton Garden Inn Louisville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Cherokee Seneca

Find the best Cherokee Seneca areas for the activities you enjoy most.
A steamboat docked at a pier with a bridge in the background.

Downtown Louisville

The cultural heart of the city beats with baseball, boxing and music, with sporting fields, live bands and a center for Muhammad Ali, the city’s most famous son.

A nighttime hot air balloon festival with colorful balloons, including one labeled "OLIVER WINERY."
Photo by Hyelsinta
Open Photo by Hyelsinta

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

A nighttime cityscape with a brightly lit bridge and a skyline featuring a prominent dome-shaped building.

St. Matthews

St. Matthews is noteworthy for its shopping, and you can make a stop at top attractions like Mall St. Matthews and Saint Matthews Pavilion Shopping Center.

A narrow stream with a rocky bridge, surrounded by trees and greenery.
Photo by throwingsofas
Open Photo by throwingsofas

Phoenix Hill

While Phoenix Hill isn't home to many top sights, Nulu Market Place and Louisville Slugger Field are some notable places to visit nearby.

A city skyline at dusk with illuminated buildings reflecting on the water.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

Top Cherokee Seneca Hotel Reviews

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

8/10 Good
"Hotel was nice. We had a large king suite. It was nice and clean. Didn’t have much of a view but we were only there for a night. Overall hotel was great. Several bars onsite. And Swizzle was amazing for dinner, views and ambiance! The filet mignon was unreal! I can’t stop talking about it. The only downside was there was no bottled water in the room. Had to go to nearby vending machine."
Megan 1-night trip
Posted 3 hours ago
Galt House Hotel Trademark Collection by Wyndham

Frequently asked questions

What is Cherokee Seneca like?
You'll be sure to have fun exploring Louisville's Cherokee Seneca neighbourhood.
If I need to cancel my hotel reservation in Cherokee Seneca, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to review the best deals in Cherokee Seneca.
What is there to do around this Louisville neighbourhood?
Peterson-Dumesnil House, Historic Frankfort Avenue and Colonel Sanders' Grave are just a few of the places to visit in and around Cherokee Seneca. Norton Fine Arts Center and Muhammad Ali Gravesite are also worth a visit when you're out sightseeing in Louisville.